Binding studies of [18F]-fluoride and polyphosphonates radiolabelled with [111In], [99mTc], [153Sm], and [188Re] on bone compartments: A new model for the pre vivo evaluation of bone seekers?

Bone

Volumn 34, Issue 5, 2004, Pages 835-844

  Mitterhauser, Markus ^a,b   Tögel, Stefan ^a,b   Wadsak, Wolfgang ^a,b,c   Mien, Leonhard Key ^a,b   Eidherr, Harald ^a,b   Wiesner, Karoline ^a   Viernstein, Helmut ^b   Kletter, Kurt ^a   Dudczak, Robert ^a,c  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY OF VIENNA   (Austria)

^c LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

Author keywords

Binding studies; Bone; Fluorine 18; Polyphosphonates; Technetium 99m

Indexed keywords

BALANCED SALT SOLUTION; CALCIUM PHOSPHATE; COLLAGEN; FLUORINE 18; HYDROXYAPATITE; INDIUM 111; LEXIDRONAM SAMARIUM IN 111; LEXIDRONAM SAMARIUM RE 188; LEXIDRONAM SAMARIUM SM 153; LEXIDRONAM SAMARIUM TC 99M; MEDRONATE TECHNETIUM TC 99M; PHOSPHONIC ACID DERIVATIVE; RADIOISOTOPE; RHENIUM 188; SAMARIUM 153; TECHNETIUM 99M; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BONE; CALCULATION; CONTROLLED STUDY; EVALUATION; FILTRATION; GAMMA RADIATION; IN VIVO STUDY; INCUBATION TIME; ISOTOPE LABELING; KINETICS; MEASUREMENT; NONHUMAN; RADIOACTIVITY; SUSPENSION;

BONE NEOPLASMS; FLUORIDES; HUMANS; MODELS, BIOLOGICAL; PHOSPHONIC ACIDS; RADIOISOTOPES;

EID: 2342468807     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2004.01.011     Document Type: Article

References (35)

1. 113mIn-labeled bone scanning agents. Radiology. 117:1975;727-730
2. Subramanian G., McAfee J.G., Rosenstreich M., Coco M. Indium-113m-labeled polyfunctional phosphonates as bone-imaging agents. J. Nucl. Med. 16:1975;1080-1084
3. Chilton H.M., Francis M.D., Thrall J.H. Radiopharmaceuticals for bone and bone marrow imaging. Swanson D.P., Chilton H.M., Thrall J.H. Pharmaceuticals in medical imaging. 1990;537-563 Macmillan, New York
4. Francis M.D., Fogelman I. [99mTc] diphosphonate uptake mechanisms on bone. Bone scanning in clinical practice. 1987;7-18 Springer Verlag, London
5. 186ReHEDP. Inorg. Chem. 36:1997;3055-3063
6. 188Re] using different carriers for "cross complexation" Appl. Radiat. Isot. 2003;. [in press]
7. Mitterhauser M., Krcal A., Dudczak R., Traub T., Oflouglu S., Viernstein H., et al. Synthesis of 99mTc EDTMP using perrhenic acid as carrier - Radiopharmaceutical and clinical results. Eur. J. Nucl. Med. 28:2001;1028
8. Füger B., Mitterhauser M., Wadsak W., Ofluoglu S., Traub T., Karanikas G., et al. Bone lesion detection with carrier added Tc-99m EDTMP in comparison to Tc-99m DPD. Nucl. Med. Commun. 2004;. [in press]
9. Francis M.D., Ferguson D.L., Tofe A.J., Bevan J.A., Michaels S.E. Comparative evaluation of three diphosphonates: in vitro adsorption (C-14 labeled) and in vivo osteogenic uptake (Tc-99m complexed). J. Nucl. Med. 21:1980;1185-1189
10. Kanishi D. 99mTc-MDP accumulation mechanisms in bone. Oral Surg., Oral Med., Oral Pathol. 75:1993;239-246
11. Nicolay O.F., Heeley J.D., Jeffcoat M.K., Jones A.G. Autoradiographic localization of technetium-99m methylene diphosphonate in growth sites of young mice. Int. J. Radiat. Appl. Instrum., Part B, Nucl. Med. Biol. 15:1988;157-163
12. Beyer G.J., Offord R., Künzi G., Aleksandrova Y., Ravn U., Jahn S., et al. The influence of EDTMP-concentration on the biodistribution of radio-lanthanides and 225Ac in tumor-bearing mice. Nucl. Med. Biol. 24:1997;367-372
13. Okamoto Y. Accumulation of technetium-99m methylene diphosphonate. Conditions affecting adsorption to hydroxyapatite. Oral Surg., Oral Med., Oral Pathol., Oral Radiol., Endod. 80:1995;115-119
14. Láznícek M., Láznícková A., Budský F., Prokop J., Kopicka K. Comparison of biological characteristics of EDTMP complexes with 99mTc, 111In and 153Sm in rats. Appl. Radiat. Isot. 45:1994;949-953
15. Blau M., Nagler W., Bender M.A. Fluorine-18: a new isotope for bone scanning. J. Nucl. Med. 3:1962;332-334
16. French R.J., McCready V.R. The use of 18F for bone scanning. Br. J. Radiol. 40:1967;655-661
17. Hoh C.K., Hawkins R.A., Dahlbom M., Glaspy J.A., Seeger L.L., Choi Y., et al. Whole body skeletal imaging with (18F) fluoride ion and PET. J. Comput. Assist. Tomogr. 17:1993;34-41
18. Schwartz Z., Shani J., Soskolne W.A., Touma H., Amir D., Sela J. Uptake and biodistribution of technetium-99m-MD32P during rat tibial bone repair. J. Nucl. Med. 34:1993;104-108
19. 32P]diphosphonate during endosteal healing around titanium, stainless steel and hydroxyapatite implants in rat tibial bone. Biomaterials. 16:1995;1373-1380
20. Shani J., Amir D., Soskolne W.A., Schwartz Z., Chisin R., Sela J. Correlations between uptake of technetium, calcium, phosphate and mineralization in rat tibial bone repair. J. Nucl. Med. 31:1990;2011-2014
21. Lysell L., Rohlin M. Initial Tc-99m diphosphonate uptake in mineralized and demineralized bone implants in rats. Int. J. Oral Surg. 14:1985;371-375
22. Chisin R., Gazit D., Ulmansky M., Laron A., Atlan H., Sela J. 99mTc-MDP uptake and histological changes during rat bone marrow regeneration. Int. J. Radiat. Appl. Instrum., B. 15:1988;469-476
23. Robertson W.G., Morgan D.B., Fleisch H., Francis M.D. The effects of diphosphonates on the exchangeable and non-exchangeable calcium and phosphate of hydroxyapatite. Biochim. Biophys. Acta. 261:1972;517-525
24. Huigen Y.M., Krips H.J., Hulleman S., Gelsema W.J., De Ligny C.L. The adsorption of 99mTc(Sn)-diphosphonate complexes on tri-calciumphosphate: the influence of preparation conditions. Ligand-type incubation media and adsorption conditions. The reversibility of the adsorption. Int. J. Radiat. Appl. Instrum., Part A, Appl. Radiat. Isot. 41:1990;189-194
25. Lin W.Y., Hsieh J.F., Lin C.P., Hsieh B.T., Ting G., Wang S.J., et al. Effect of reaction conditions on preparations of rhenium-188 hydroxyethylidene diphosphonate complexes. Nucl. Med. Biol. 26:1999;455-459
26. Palmedo H., Guhlke S., Bender H., Sartor J., Schoeneich G., Risse J., et al. Dose escalation study with rhenium-188 hydroxyethylidene diphosphonate in prostate cancer patients with osseous metastases. Eur. J. Nucl. Med. 27:2000;123-130
27. Oh S.J., Won K.S., Moon D.H., Cheon J.H., Ha H.J., Jeong J.M., et al. Preparation and biological evaluation of 188Re-ethylenediamine-N, N, N′, N′-tetrakis(methylene phosphonic acid) as a potential agent for bone pain palliation. Nucl. Med. Commun. 23:2002;75-81
28. Bergqvist L., Brismar J., Cederquist E., Darte L., Naversten Y., Palmer J. Clinical comparison of bone scintigraphy with 99Tcm-DPD, 99Tcm-HDP and 99Tcm-MDP. Acta Radiol., Diagn. 25:1984;217-223
29. Vorne M., Vahatalo S., Lantto T. A clinical comparison of 99mTc-DPD and two 99mTc-MDP agents. Eur. J. Nucl. Med. 8:1983;395-397
30. Buell U., Kleinhans E., Zorn-Bopp E., Reuschel W., Muenzing W., Moser E.A., et al. A comparison of bone imaging with Tc-99m DPD and Tc-99m MDP: concise communication. J. Nucl. Med. 23:1982;214-217
31. Schroth H.J., Hausinger F., Garth H., Oberhausen E. Comparison of the kinetics of methylene-diphosphonate (MDP) and dicarboxypropan-diphosphonic acid (DPD), two radio-diagnostics for bone scintigraphy. Eur. J. Nucl. Med. 9:1984;529-532
32. Mele M., Conte E., Fratello A., Pasculli D., Pieralice M., D'Addabbo A. Computer analysis of Tc-99m DPD and Tc-99m MDP kinetics in humans: concise communication. J. Nucl. Med. 24:1983;334-338
33. Pauwels E.K., Blom J., Camps J.A., Hermans J., Rijke A.M. A comparison between the diagnostic efficacy of 99mTc-MDP, 99mTc-DPD and 99mTc-HDP for the detection of bone metastases. Eur. J. Nucl. Med. 8:1983;118-122
34. Fruhling J., Verbist A., Balikdjian D. Which diphosphonate for routine bone scintigraphy (MDP, HDP or DPD)? Nucl. Med. Commun. 7:1986;415-425
35. Blake G.M., Park-Holohan S.J., Cook G.J., Fogelman I. Quantitative studies of bone with the use of 18F-fluoride and 99mTc-methylene diphosphonate. Semin. Nucl. Med. 31:2001;28-49