High-performance liquid chromatographic-UV detection analysis of ceftiofur and its active metabolite desfuroylceftiofur in horse plasma and synovial fluid after regional intravenous perfusion and systemic intravenous injection of ceftiofur sodium

Analytica Chimica Acta

Volumn 512, Issue 1, 2004, Pages 75-84

  De Baere, S ^a   Pille, F ^a   Croubels, S ^a   Ceelen, L ^a   De Backer, P ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

Ceftiofur; Horse plasma; HPLC UV

Indexed keywords

CALIBRATION; COSTS; DERIVATIVES; GRAPH THEORY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SOLVENTS; ULTRAVIOLET DETECTORS;

QUANTITATIVE DETERMINATION; REAGENTS; SOLID-PHASE EXTRACTION COLUMN; SYNOVIAL FLUID;

BIOCHEMISTRY;

ACETONITRILE; CEFAPIRIN; CEFTIOFUR; CEPHALOSPORIN; DESFUROYLCEFTIOFURACETAMIDE; DITHIOERYTHRITOL; DRUG METABOLITE; IODOACETAMIDE; THIOL DERIVATIVE; TRIFLUOROACETIC ACID; UNCLASSIFIED DRUG;

ANALYTICAL EQUIPMENT; ANIMAL EXPERIMENT; ARTICLE; CALIBRATION; COST BENEFIT ANALYSIS; DERIVATIZATION; DRUG BLOOD LEVEL; DRUG SYNOVIAL FLUID LEVEL; ELUTION; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; PLASMA; PRIORITY JOURNAL; QUANTITATIVE ASSAY; SOLID PHASE EXTRACTION; SYNOVIAL FLUID; ULTRAVIOLET RADIATION;

EQUIDAE; EQUUS CABALLUS;

EID: 2342464081     PISSN: 00032670     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aca.2004.02.017     Document Type: Article

References (23)

1. Folz S.D., Hanson B.J., Griffin A.K. Equine Vet. J. 24:1992;300-304
2. Guglick M.A., MacAllister C.G., Clarke C.R., Pollet R., Hague C., Clarke J.M. Am. J. Vet. Res. 59:1998;458-463
3. Mills M.L., Rush B.R., St. Jean G., Gaughan E.M., Mosier D., Gibson E., Freeman L. Vet. Surg. 29:2000;398-406
4. Jaglan P.S., Kubicek M.F., Arnold T.S., Cox B.L., Robins R.H., Johnson D.B., Gilbertson T.J. J. Agric. Food Chem. 37:1989;1112-1118
5. Jaglan P.S., Yein F.S., Hornish R.E., Cox B.L., Arnold T.S., Roof R.D., Gilbertson T.J. J. Dairy Sci. 75:1992;1870-1876
6. Gilbertson T.J., Roof R.D., Nappier J.L., Zaya M.J., Robins R.H., Stuart D.J., Krzeminski L.F., Jaglan P.S. J. Agric. Food Chem. 43:1995;229-234
7. Beconi-Barker M.G., Roof R.D., Millerioux L., Kausche F.M., Vidmar T.J., Smith E.B., Callahan J.K., Hubbard V.L., Smith G.A., Gilbertson T.J. J. Chromatogr. B. 673:1995;231-244
8. Jaglan P.S., Roof R.D., Yein F.S., Arnold T.S., Brown S.A., Gilbertson T.J. J. Vet. Pharmacol. Ther. 17:1994;24-30
9. Bennett J.V., Brodie J.L., Benner E.J. Appl. Microbiol. 14:1966;170-177
10. Meyer J.C., Brown M.P., Gronwall R.R., Merritt K. Equine Vet. J. 24:1992;485-486
11. Cervantes C.C., Brown M.P., Gronwall R., Merritt K. Am. J. Vet. Res. 54:1993;573-575
12. Navarre C.B., Zhang L., Sunkara G., Duran S.H., Kompella U.B. J. Vet. Pharmacol. Ther. 22:1999;13-19
13. Jaglan P.S., Cox B.L., Arnold T.S., Kubicek M.F., Stuart D.J., Gilbertson T.J. J. Assoc. Off. Anal. Chem. 73:1990;26-30
14. Keever J., Voyksner R.D., Tyczkowska K.L. J. Chromatogr. A. 794:1998;57-62
15. Sörensen L.K., Snor L.K. J. Chromatogr. A. 882:2000;145-151
16. Bruno F., Curini R., Di Corcia A., Nazzari M., Samperi R. J. Agric. Food Chem. 49:2001;3463-3470
17. F. Pille, S. De Baere, L. Ceelen, J. Dewulf, S. Croubels, F. Gasthuys, P. De Backer, A. Martens, Determination of synovial fluid and plasma concentrations of ceftiofur following regional intravenous perfusion in the horse, Vet. Surg., in press.
18. Commission Decision of 12 August 2002, implementing Council Directive 96/23/EC concerning the performance of analytical methods and the interpretation of results, 2002/657/EC, Off. J. Eur. Commun., L221/8, 17 August 2002.
19. R.J. Heitzman (Ed.), Veterinary drug residues, residues in food producing animals and their products: reference materials and methods, Report Eur. 15127-EN, Office for Official Publications of the European Communities, Brussels, 1994.
20. Knecht J., Stork G. Z. Anal. Chem. 270:1974;97-99
21. Van Bavel M., Boot A., Bravenboer J., de Goey F., Maas C., van der Putten A., Verwaal W. De Ware(n) Chemicus. 26:1996;1-16
22. Draft Volume 8, Notice to Applicants, Veterinary Medicinal Products: Establishment of Maximum Residue Limits (MRLs) for Residues of Veterinary Products in Foodstuffs of Animal Origin: Development and Validation of a Proposed Regulatory Method, EMEA/CVMP/573/00-Final, 2000.
23. Miller J.N. Spectrosc. Int. 3:1991;45-47