Midkine promoter can mediate transcriptional activation of a fused suicide gene in a broader range of human breast cancer Compared with c-erbB-2 promoter

Oncology

Volumn 66, Issue 2, 2004, Pages 143-149

  Yu, Ling ^a   Yamamoto, Naohito ^a   Kadomatsu, Kenji ^b   Muramatsu, Takashi ^b   Matsubara, Shuichiro ^c   Sakiyama, Shigeru ^a   Tagawa, Masatoshi ^a  

^a CHIBA CANCER CENTER   (Japan)

^b NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

Breast cancer; C erbB 2; Herpes simplex virus thymidine kinase; Midkine; Promoter

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; GANCICLOVIR; MIDKINE; PRODRUG; THYMIDINE KINASE; VIRUS ENZYME;

ADULT; AGED; ARTICLE; BREAST CARCINOMA; CANCER CELL CULTURE; CANCER GENETICS; CLINICAL ARTICLE; CONTROLLED STUDY; GENE CONTROL; GENE EXPRESSION; GENE FUSION; GENETIC TRANSFECTION; HERPES SIMPLEX VIRUS; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; PROMOTER REGION; SAMPLING; SUICIDE GENE; TRANSCRIPTION INITIATION; UPREGULATION;

ADULT; AGED; BLOTTING, NORTHERN; BREAST; BREAST NEOPLASMS; CARRIER PROTEINS; CELL LINE, TUMOR; CULTURE TECHNIQUES; CYTOKINES; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, ERBB-2; GENES, TRANSGENIC, SUICIDE; HUMANS; MIDDLE AGED; PROMOTER REGIONS (GENETICS); SIMPLEXVIRUS; THYMIDINE KINASE; TRANS-ACTIVATION (GENETICS); UP-REGULATION;

EID: 2342454321     PISSN: 00302414     EISSN: None     Source Type: Journal    
DOI: 10.1159/000077441     Document Type: Article

References (21)

1. Miller N, Whelan J: Progress in transcriptionally targeted and regulatable vectors for genetic therapy. Hum Gene Ther 1997;8:803-815.
2. Nettelbeck DM, Jérôme V, Müller R: Gene therapy: Designer promoters for tumour targeting. Trends Genet 2000;16:174-181.
3. Gómez-Navarro J, Curiel DT, Douglas JT: Gene therapy for cancer. Eur J Cancer 1999;35: 2039-2057.
4. Hynes NE, Stern DF: The biology of erbB-2/ neu/HER-2 and its role in cancer. Biochim Biophys Acta 1994;1198:165-184.
5. Wang S, Hung M: HER2 overexpression and cancer targeting. Semin Oncol 2001;28:115-124.
6. Hollywood DP, Hurst HC: A novel transcription factor, OB2-1, is required for overexpression of the proto-oncogene c-erbB-2 in mammary tumour lines. EMBO J 1993;12:2369-2375.
7. Ring CJA, Harris JD, Hurst HC, Lemoine NR: Suicide gene expression induced in tumour cells transduced with recombinant adenoviral, retroviral and plasmid vectors containing the ERBB2 promoter. Gene Ther 1996;3:1094-1103.
8. Maeda T, O-Wang J, Matsubara H, Asano T, Ochiai T, Sakiyama S, Tagawa T: A minimum c-erbB-2 promoter-mediated expression of herpes simplex virus thymidine kinase gene confers selective cytotoxicity of human breast cancer cells to ganciclovir. Cancer Gene Ther 2001;8:890-896.
9. Pandha HS, Martin L-A, Rigg A, Hurst HC, Stamp GWH, Sikora K, Lemoine NR: Genetic prodrug activation therapy for breast cancer: A phase I clinical trial of erbB-2-directed suicide gene expression. J Clin Oncol 1999;17:2180-2189.
10. Choudhuri R, Zhang HT, Donnini S, Ziche M, Bicknell R: An angiogenic role for the neurokines midkine and pleiotrophin in tumorigenesis. Cancer Res 1997;57:1814-1819.
11. Kadomatsu K, Hagihara M, Akhter S, Fan QW, Muramatsu H, Muramatsu T: Midkine induces the transformation of NIH3T3 cells. Br J Cancer 1997;75:354-359.
12. Tsutsui J, Kadomatsu K, Matsubara S, Nakagawara A, Hamanoue M, Takao S, Shimazu H, Ohi Y, Muramatsu T: A new family of heparin-binding growth/differentiation factors: Increased midkine expression in Wilms' tumor and other human carcinomas. Cancer Res 1993;53:1281-1285.
13. Aridome K, Tsutsui J, Takao S, Kadomatsu K, Ozawa M, Aikou T, Muramatsu T: Increased midkine gene expression in human gastrointestinal cancers. Jpn J Cancer Res 1995;86:655-661.
14. Miyauchi M, Yoshida Y, Tada Y, Narita M, Maeda T, Bahar R, Kadomatsu K, Muramatsu T, Matsubara S, Nakagawara A, Sakiyama S, Tagawa M: Expression of herpes simplex virus-thymidine kinase gene controlled by a promoter region of the midkine gene confers selective cytotoxicity to ganciclovir in human carcinoma cells. Int J Cancer 2001;91:723-727.
15. Yoshida Y, Tomizawa M, Bahar R, Miyauchi M, Yamaguchi T, Saisho H, Kadomatsu K, Muramatsu T, Matsubara S, Sakiyama S, Tagawa M: A promoter region of midkine gene can activate transcription of an exogenous suicide gene in human pancreatic cancer. Anticancer Res 2002;22:117-120.
16. Garver RI Jr, Radford DM, Donis-Keller H, Wick MR, Milner PG: Midkine and pleiotrophin expression in normal and malignant breast tissue. Cancer 1994;74:1584-1590.
17. Miyashiro I, Kaname T, Shin E, Wakasugi E, Monden T, Takatsuka Y, Kikkawa N, Muramatsu T, Monden M, Akiyama T: Midkine expression in human breast cancers: Expression of truncated form. Breast Cancer Res Treat 1997;43:1-6.
18. Coussens L, Yang-Feng TL, Liao YC, Chen E, Gray A, McGrath J, Seeburg PH, Libermann TA, Schlessinger J, Francke U, Levinson A, Ullrich A: Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. Science 1985;230:1132-1139.
19. Kadomatsu K, Tomomura M, Muramatsu T: cDNA cloning and sequencing of a new gene intensely expressed in early differentiation stages of embryonal carcinoma cells and in mid-gestation period of mouse embryogenesis. Biochem Biophys Res Commun 1988;151:1312-1318.
20. Uehara K, Matsubara S, Kadomatsu K, Tsutsui J, Muramatsu T: Genomic structure of human midkine (MK), a retinoic acid-responsive growth/ differentiation factor. J Biochem 1992;111:563-567.
21. Heise C, Kirn DH: Replication-selective adenoviruses as oncolytic agents. J Clin Invest 2000;105:847-851.