Accumulation of ivermectin in the brain of sea bream, Sparus aurata after intraperitoneal administration

Environmental Toxicology and Pharmacology

Volumn 17, Issue 1, 2004, Pages 9-12

  Katharios, Pantelis ^a   Pavlidis, Michalis ^b   Iliopoulou Georgudaki, Joan ^a  

^a UNIVERSITY OF PATRAS   (Greece)

^b UNIVERSITY OF CRETE   (Greece)

Author keywords

Brain; CNS; Ivermectin; Multidrug resistance; P glycoproteins; Sea bream

Indexed keywords

IVERMECTIN;

ARTICLE; BIOACCUMULATION; BLOOD BRAIN BARRIER; BRAIN; CONCENTRATION (PARAMETERS); DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG UPTAKE; ENZYME LINKED IMMUNOSORBENT ASSAY; NONHUMAN; PRIORITY JOURNAL; SEA BREAM; SPARUS AURATA;

ARCHOSARGUS RHOMBOIDALIS; HYPEROGLYPHE POROSA; SPARUS; SPARUS AURATA; TELEOSTEI; VERTEBRATA;

EID: 2342451297     PISSN: 13826689     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etap.2004.01.003     Document Type: Article

References (25)

1. Athanassopoulou F., Bouboulis D., Martinsen B. In vitro treatments of deltamethrin against the isopod parasite Cerathoa oestroides, a pathogen of seabass Dicentrarchus labrax. L. Bull. Eur. Assoc. Fish Pathol. 21(1):2001a;26-29
2. Athanassopoulou F., Ragias V., Roth M., Liberis N., Hatzinikolaou S. Toxicity and pathological effects of orally and intraperitoneally administered ivermectin in sea bass. D. labrax L. Dis. Aquat. Organ. 52(1):2002;69-76
3. Athanassopoulou F., Ragias V., Tavla J., Christofilloyannis P., Liberis N. Preliminary trials on the efficacy of ivermectin against Lernathropus kroyeri (Crustacea) in cultured sea bass. D. labrax L. Aquacult. Res. 32:2001b;77-79
4. Bard S.M. Multixnobiotic resistance as a cellular defence mechanism in aquatic organisms. Aquat. Toxicol. 48:2000;357-389
5. Bard S.M., Bello S.M., Hahn M.E., Stegeman J.J. Expression of Pglycoprotein in killifish (Fundulus heteroclitus) exposed to environmental xenobiotics. Aquat. Toxicol. 59:2002a;237-251
6. Bard S.M., Woodin B.R., Stegeman J.J. Expression of P-glycoprotein and cytochrome p450 1A in intertidal fish (Anoplarchus purpurescens) exposed to environmental contaminants. Aquat. Toxicol. 60:2002b;17-32
7. Chan K.M., Davies P.L., Childs S., Veinot L., Ling V. P-glycoprotein genes in the winter flounder, Pleuronectes americanus: isolation of two types of genomic clones carrying 3′ terminal exons. Biochim. Biophys. Acta. 1171:1992;65-72
8. Chen C., Chin J., Ueda K., Clark D., Pastan I., Gottesman F., Roninson I. Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells. Cell. 47:1986;381-389
9. Chiu, S., Lu, A., 1989. Metabolism and tissue residues. In: Campbell, W.C. (Ed.), Ivermectin and Abamectin, Springer-Verlag, New York, pp. 131-143.
10. Cooper P.S., Reece K.C., Vogelbein W.K., Van Veld P.A. P-glycoprotein and sister P-glycoprotein sequences from mummichog, Fundulus heteroclitus, liver and intestine. Mar. Environ. Res. 50:2000;335
11. Crooks S.R.H., Baxter G.A., Traynor I.M., Elliott C.T., McCaughey W.J. Detection of ivermectin residues in bovine liver using an enzyme immunoassay. Analyst. 123:1998;355-358
12. Davies I.M., Rodger G.K. A review of the use of ivermectin as a treatment for sea lice [Lepeophtheirus salmonis (Kroyer) and Caligus elongatus Nordmann] infestation in farmed Atlantic salmon (Salmo salar L.). Aquacult. Res. 31:2000;869-883
13. Epel E. Use of multidrug transporters as first lines of defense against toxins in aquatic organisms. Comp. Biochem. Physiol. Part A. 120:1998;23-28
14. Hoy T., Horsberg E., Nafstad I. The disposition of ivermectin in Atlantic salmon (Salmo salar). Pharmacol. Toxicol. 67:1990;307-312
15. Katharios P., Iliopoulou-Georgudaki J., Kapata-Zoumbos K., Spiropoulos S. Toxicity of intraperitoneally injected ivermectin in sea bream, Sparus aurata. Fish Physiol. Biochem. 25:2001;99-108
16. Keppler D., Ringwood A.H. Expression of P-glycoprotein in southeastern oysters, Crassostrea virginica. Mar. Environ. Res. 52:2001;81-96
17. Kurelec B. The multixenobiotic resistance mechanism in aquatic organisms. Crit Rev. Toxicol. 22:1992;23-43
18. Kurelec B., Krea S., Pivcevic B., Ugarkovic D., Bachmann M., Imsiecke G., Mueller W.E.G. Expression of P-glycoprotein in marine sponges; identification and characterization of the 125 kDa drug-binding glycoprotein. Carcinogenesis (Eynsham). 13:1992;69-76
19. Lankas G.R., Cartwright M.E., Umbenhauer D. P-glycoprotein deficiency in a subpopulation of CF-1 mice enhances avermectin-induced neurotoxicity. Toxicol. Appl. Pharmacol. 143:1997;357-365
20. McFadzen I., Eufemia N., Heath C., Epel E., Moore M., Loewe D. Multidrug resistance in the embryos and larvae of the mussel Mytilus edulis. Mar. Environ. Res. 50:2000;319-323
21. Minier C., Akcha M., Galgani F. P-glycoprotein expression in Crassostrea gigas and Mytilus edulis in polluted sea water. Comp. Biochem. Physiol. 106:1993;1029-1036
22. Roth M., Richards R.H., Somerville C. Current practices in the chemotherapeutic control of sea lice infestations in aquaculture. A Rev. J. Fish Dis. 16:1993;1-26
23. Roy, W.J., Sutherland, I.H., M. Rodger, H.D., Varma, K.J., 2000. Tolerance of Atlantic salmon, Salmo salar L., and rainbow trout, Oncorhynchus mykiss (Walbaum), to emamectin benzoate, a new orally administered treatment for sea lice, Aquac. 184, 19-29.
24. Smital T., Sauerborn S. Measurement of the activity of multixenobiotic resistance mechanism in the common carp Cyprinus carpio. Mar. Environ. Res. 54:2002;449-453
25. Tutundjian R., Minier C., Le Foll F., Leboulenger F. Rhodamine exclusion activity in primary cultured turbot (Scophthalmus maximus) hepatocytes. Mar. Environ. Res. 54:2002;443-447