A meta-analysis of randomised trials suggests a survival benefit for combined radiotherapy and radical cystectomy compared with radical radiotherapy for invasive bladder cancer: Are these data relevant to modern practice?

Clinical Oncology

Volumn 16, Issue 3, 2004, Pages 166-171

  Shelley, M D ^a   Wilt, T J ^b   Barber, J ^a   Mason, M D ^a  

^a Velindre NHS Trust   (United Kingdom)

^b Minneapolis VA Ctr Chron Dis O   (United States)

Author keywords

Cystectomy; Invasive bladder cancer; Meta analysis; Radiotherapy; Systematic review

Indexed keywords

BLADDER CANCER; CANCER INVASION; CANCER RADIOTHERAPY; CANCER SURVIVAL; CLINICAL PRACTICE; CLINICAL STUDY; CLINICAL TRIAL; COCHRANE LIBRARY; CONFIDENCE INTERVAL; CYSTECTOMY; DATA ANALYSIS; EMBASE; HUMAN; KAPLAN MEIER METHOD; MEDLINE; META ANALYSIS; PRACTICE GUIDELINE; PREOPERATIVE TREATMENT; PRIORITY JOURNAL; RETROSPECTIVE STUDY; REVIEW; SALVAGE THERAPY; SURGICAL APPROACH;

EID: 2342433472     PISSN: 09366555     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clon.2003.10.001     Document Type: Article

References (26)

1. Vaidya A, Soloway MS, Hawke C, et al. De novo muscle invasive bladder cancer: is there a change in trend? J Urol 2001;165:47-50.
2. Stein JP, Lieskovsky G, Cote R, et al. Radical cystectomy in the treatment of invasive bladder cancer: long-term results in 1054 patients. J Clin Oncol 2001;19:666-775.
3. Huncharek M, Muscat J, Geschwind JF. Planned preoperative radiation therapy in muscle invasive bladder cancer: results of a meta-analysis. Anticancer Res 1998;18:1931-1934.
4. Ghoneim MA, el-Mekresh MM, el-Baz MA, et al. Radical cystectomy for carcinoma of the bladder: critical evaluation of the results in 1026 cases. J Urol 1997;158:393-399.
5. Cheng L, Slezak J, Bergstralh EJ, et al. Preoperative prediction of surgical margin status in patients with prostate cancer treated by radical prostatectomy. J Clin Oncol 2000;18:2862-2868.
6. Malavaud B, Vaessen C, Mouzin M, et al. Complications for radical cystectomy. Impact of the American Society of Anesthesiologists score. Eur Urol 2001;39:79-84.
7. Bassi P. Outcome of radical cystectomy for invasive bladder cancer. Curr Opin Urol 2000;10:459-463.
8. Borgaonkar S, Jain A, Bollina P, et al. Radical radiotherapy and salvage cystectomy as the primary management of transitional cell carcinoma of the bladder. Results following the introduction of a CT planning technique. Clin Oncol 2002;14:141-147.
9. Gospodarowicz MK, Rider WD, Keen CW, et al. Bladder cancer: long-term follow-up results of patients treated with radical radiation. Clin Oncol 1991;3:155-161.
10. Hayter CR, Paszat LF, Groome PA, et al. A population-based study of the use and outcome of radical radiotherapy for invasive bladder cancer. Int J Radiat Oncol Biol Phys 1999;45:1239-1245.
11. Clarke M, Oxman A. Analysing and presenting results. Cochrane Reviewers Handbook 4.1.6. In: The Cochrane Library. Oxford: Update Software, 2003.
12. DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986;7:177-188.
13. Bloom HJ, Hendry WF, Wallace DM, et al. Treatment of T3 bladder cancer: controlled trial of pre-operative radiotherapy and radical cystectomy versus radical radiotherapy. Br J Urol 1982; 54:136-151.
14. Wallace DM, Bloom HJ. The management of deeply infiltrating (T3) bladder carcinoma: controlled trial of radical radiotherapy versus preoperative radiotherapy and radical cystectomy (first report). Br J Urol 1976;48:587-594.
15. Miller LS, Johnson DE. Megavoltage irradiation for bladder cancer: alone, postoperative, or preoperative? In: The 7th National Cancer Conference Proceedings; 1973:771-782.
16. Miller LS. Bladder cancer: superiority of preoperative irradiation and cystectomy in clinical stages B2 and C. Cancer 1977;39(suppl 2):973-980.
17. Sell A, Jakobsen A, Nerstrom B, et al. Treatment of advanced bladder cancer category T2 T3 and T4a. A randomized multicenter study of preoperative irradiation and cystectomy versus radical irradiation and early salvage cystectomy for residual tumor. DAVECA protocol 8201. Danish Vesical Cancer Group. Scand J Urol Nephrol Suppl 1991;138:193-201.
18. Horwich A. Commentary on radiotherapy for bladder cancer. In: Hall R, ed. Clinical management of bladder cancer. London: Arnold, 1999:236-238.
19. Whitmore W, Batata M, Ghoneim M, et al. Radical cystectomy with or without prior irradiation in the treatment of bladder cancer. J Urol 1977;300:1242-1245.
20. Zelen M. A new design for randomized clinical trials. N Engl J Med 1979;300:1242-1245.
21. Turner W, Struder U. Cystectomy, bladder reconstruction, urinary diversion and stomatherapy. In: Hall R, ed. Clinical management of bladder cancer. London: Arnold, 1999:171-211.
22. Tsujii H, Gospodarowicz M, Bolla M, et al. The place of radiotherapy for localised invasive bladder cancer. Urol Oncol 1998; 4:145-153.
23. Scher H, Shipley W, Herr H. Cancer of the bladder. In: DeVita V, Hellman S, Rosenberg S, eds. Cancer principles and practice of oncology. Philadelphia: Lippencott-Raven, 1997:1300-1322.
24. Shelley MD, Barber J, Wilt T, et al. Surgery versus radiotherapy for muscle invasive bladder cancer. In: The Cochrane Database of Systematic Reviews: Oxford, Update Software, 2002.
25. Sengelov L, von der Maase H. Radiotherapy in bladder cancer. Radiother Oncol 1999;52:1-14.
26. Bassi P. Outcome of radical cystectomy for invasive bladder cancer. Curr Opin Urol 2000;10:459-463.