Apparent CBF decrease with normal aging due to partial volume effects: MR-based partial volume correction on CBF SPECT

Annals of Nuclear Medicine

Volumn 19, Issue 4, 2005, Pages 283-290

  Inoue, Kentaro ^a   Ito, Hiroshi ^a   Goto, Ryoi ^a   Nakagawa, Manabu ^a   Kinomura, Shigeo ^a   Sato, Tachio ^a   Sato, Kazunori ^a   Fukuda, Hiroshi ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

Age; Brain atrophy; MRI; Partial volume effects; SPECT

Indexed keywords

CYSTEINE ETHYL ESTER TC 99M;

ADULT; AGE DISTRIBUTION; AGING; ARTICLE; BRAIN BLOOD FLOW; BRAIN BLOOD VOLUME; FEMALE; GRAY MATTER; HUMAN; LATERAL BRAIN VENTRICLE; MALE; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PREFRONTAL CORTEX; PRIORITY JOURNAL; SEX DIFFERENCE; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; WHITE MATTER;

EID: 23344440452     PISSN: 09147187     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02984620     Document Type: Article

References (46)

1. Goto R, Kawashima R, Ito H, Koyama M, Sato K, Ono S, et al. A comparison of Tc-99m HMPAO brain SPECT images of young and aged normal individuals. Ann Nucl Med 1998; 12: 333-339.
2. 99mTc-d,l-HMPAO and SPECT of the brain in normal aging. J Cereb Blood Flow Metab 1991; 11: 508-521.
3. Markus H, Ring H, Kouris K, Costa D. Alterations in regional cerebral blood flow, with increased temporal interhemispheric asymmetries, in the normal elderly: an HMPAO SPECT study. Nucl Med Commun 1993; 14: 628-633.
4. 99mTc-ECD brain perfusion SPET: variability, asymmetry and effects of age and gender in healthy adults. Eur J Nucl Med 2001; 28: 873-887.
5. 99mTc-HMPAO SPET study. Eur J Nucl Med 1996; 23: 1329-1337.
6. Mozley PD, Sadek AM, Alavi A, Gur RC, Muenz LR, Bunow BJ, et al. Effects of aging on the cerebral distribution of technetium-99m hexamethylpropylene amine oxime in healthy humans. Eur J Nucl Med 1997; 24: 754-761.
7. Martin AJj, Friston KJ, Colebatch JG, Frackowiak RS. Decreases in regional cerebral blood flow with normal aging. J Cereb Blood Flow Metab 1991; 11: 684-689.
8. 99mTc-HMPAO SPECT. Neuroradiology 1998; 40: 428-434.
9. Claus JJ, Breteler MM, Hasan D, Krenning EP, Bots ML, Grobbee DE, et al. Regional cerebral blood flow and cerebrovascular risk factors in the elderly population. Neurobiol Aging 1998; 19: 57-64.
10. Gur RC, Gur RE, Obrist WD, Hungerbuhler JP, Younkin D, Rosen AD, et al. Sex and handedness differences in cerebral blood flow during rest and cognitive activity. Science 1982; 217: 659-661.
11. Rodriguez G, Warkentin S, Risberg J, Rosadini G, Sex differences in regional cerebral blood flow. J Cereb Blood Flow Metab 1988; 8: 783-789.
12. Pagani M, Salmaso D, Jonsson C, Hatherly R, Jacobsson H, Larsson SA, et al. Regional cerebral blood flow as assessed by principal component analysis and (99m)Tc-HMPAO SPET in healthy subjects at rest: normal distribution and effect of age and gender. Eur J Nucl Med Mol Imaging 2002; 29: 67-75.
13. Jones K, Johnson KA, Becker JA, Spiers PA, Albert MS, Holman BL. Use of singular value decomposition to characterize age and gender differences in SPECT cerebral perfusion. J Nucl Med 1998; 39: 965-973.
14. Hoffman EJ, Huang SC, Phelps ME. Quantitation in positron emission computed tomography: 1. Effect of object size. J Comput Assist Tomogr 1979; 3: 299-308.
15. Meltzer CC, Leal JP, Mayberg HS, Wagner HN Jr, Frost JJ. Correction of PET data for partial volume effects in human cerebral cortex by MR imaging. J Comput Assist Tomogr 1990; 14: 561-570.
16. Muller-Gartner HW, Links JM, Prince JL, Bryan RN, Mcveigh E, Leal JP, et al. Measurement of radiotracer concentration in brain gray matter using positron emission tomography: MRI-based correction for partial volume effects. J Cereb Blood Flow Metab 1992; 12: 571-583.
17. Strul D, Bendriem B, Robustness of anatomically guided pixel-by-pixel algorithms for partial volume effect correction in positron emission tomography. J Cereb Blood Flow Metab 1999; 19: 547-559.
18. Rousset OG, Ma Y, Evans AC. Correction for partial volume effects in PET: principle and validation. J Nucl Med 1998; 39: 904-911.
19. Videen TO, Perlmutter JS, Mintun MA, Raichle ME. Regional correction of positron emission tomography data for the effects of cerebral atrophy. J Cereb Blood Flow Metab 1988; 8: 662-670.
20. Ashburner J, Friston KJ. Voxel-based morphometry-the methods. Neuroimage 2000; 11: 805-821.
21. Goldszal AF, Davatzikos C, Pham DL, Yan MX, Bryan RN, Resnick SM. An image-processing system for qualitative and quantitative volumetric analysis of brain images. J Comput Assist Tomogr 1998; 22: 827-837.
22. Resnick SM, Pham DL, Kraut MA, Zonderman AB, Davatzikos C. Longitudinal magnetic resonance imaging studies of older adults: a shrinking brain. J Neurosci 2003; 23: 3295-3301.
23. Good CD, Johnsrude IS, Ashburner J, Henson RN, Friston KJ, Frackowiak RSJ. A voxel-based morphometric study of ageing in 465 normal adult human brains. Neuroimage 2001; 14: 21-36.
24. Good CD, Johnsrude I, Ashburner J, Henson RN, Friston KJ, Frackowiak RS. Cerebral asymmetry and the effects of sex and handedness on brain structure: a voxel-based morphometric analysis of 465 normal adult human brains. Neuroimage 2001; 14: 685-700.
25. Van Laere KJ, Dierckx RA. Brain perfusion SPECT: age- and sex-related effects correlated with voxel-based morphometric findings in healthy adults. Radiology 2001; 221: 810-817.
26. Inoue K, Nakagawa M, Goto R, Kinomura S, Sato T, Sato K, et al. Regional differences between (99m)Tc-ECD and (99m)Tc-HMPAO SPET in perfusion changes with age and gender in healthy adults. Eur J Nucl Med Mol Imaging 2003; 30: 1489-1497.
27. Ibanez V, Pietrini P, Alexander GE, Furey ML, Teichberg D, Rajapakse JC, et al. Regional glucose metabolic abnormalities are not the result of atrophy in Alzheimer's disease. Neurology 1998; 50: 1585-1593.
28. Labbe C, Froment JC, Kennedy A, Ashburner J, Cinotti L. Positron emission tomography metabolic data corrected for cortical atrophy using magnetic resonance imaging. Alzheimer Dis Assoc Disord 1996; 10: 141-170.
29. Matsuda H, Kanetaka H, Ohnishi T, Asada T, Imabayashi E, Nakano S, et al. Brain SPET abnormalities in Alzheimer's disease before and after atrophy correction. Eur J Nucl Med Mol Imaging 2002; 29: 1502-1505.
30. Meltzer CC, Cantwell MN, Greer PJ, Ben-Eliezer D, Smith G, Frank G, et al. Does cerebral blood flow decline in healthy aging? A PET study with partial-volume correction. J Nucl Med 2000; 41: 1842-1848.
31. Matsuda H, Ohnishi T, Asada T, Li ZJ, Kanetaka H, Imabayashi E, et al. Correction for partial-volume effects on brain perfusion SPECT in healthy men. J Nucl Med 2003; 44: 1243-1252.
32. Koyama M, Kawashima R, Ito H, Ono S, Sato K, Goto R, et al. SPECT imaging of normal subjects with technetium-99m-HMPAO and technetium-99m-ECD. J Nucl Med 1997; 38: 587-592.
33. Ashburner J, Friston KJ. Multimodal image coregistration and partitioning-a unified framework. Neuroimage 1997; 6: 209-217.
34. Rorden C, Brett M. Stereotaxic display of brain lesions. Behav Neurol 2000; 12: 191-200.
35. Ashburner J, Neelin P, Collins DL, Evans A, Friston KJ. Incorporating prior knowledge into image registration. Neuroimage 1997; 6: 344-352.
36. Ashburner J, Friston KJ. Nonlinear spatial normalization using basis functions. Hum Brain Mapp 1999; 7: 254-266.
37. Benjamini Y, Hochberg Y. Controlling the False Discovery Rate: a Practical and Powerful Approach to Multiple Testing. J Royal Stat Soc B 1995; 57: 289-300.
38. Yekutieli D, Benjamini Y. Resampling based false discovery controlling multiple test procedures for correlated test statistics. J Statist Plann Inference 1999; 82: 171-196.
39. Genovese CR, Lazar NA, Nichols T. Thresholding of statistical maps in functional neuroimaging using the false discovery rate. Neuroimage 2002; 15: 870-878.
40. Taki Y, Goto R, Evans A, Zijdenbos A, Neelin P, Lerch J, et al. Voxel-based morphometry of human brain with age and cerebrovascular risk factors. Neurobiol Aging 2004; 25: 455-463.
41. Raz N, Gunning FM, Head D, Dupuis JH, Mcquain J, Briggs SD, et al. Selective aging of the human cerebral cortex observed in vivo: differential vulnerability of the prefrontal gray matter. Cereb Cortex 1997; 7: 268-282.
42. Bencherif B, Stumpf MJ, Links JM, Frost JJ. Application of MRI-Based Partial-Volume Correction to the Analysis of PET Images of micro-Opioid Receptors Using Statistical Parametric Mapping. J Nucl Med 2004; 45: 402-408.
43. Xu J, Kobayashi S, Yamaguchi S, Iijima K-I, Okada K, Yamashita K. Gender Effects on Age-Related Changes in Brain Structure. AJNR Am J Neuroradiol 2000; 21: 112-118.
44. Gur RC, Mozley PD, Resnick SM, Gottlieb GL, Kohn M, Zimmerman R, et al. Gender differences in age effect on brain atrophy measured by magnetic resonance imaging. Proc Natl Acad Sci USA 1991; 88: 2845-2849.
45. Longstreth WT Jr, Arnold AM, Manolio TA, Burke GL, Bryan N, Jungreis CA, et al. Clinical correlates of ventricular and sulcal size on cranial magnetic resonance imaging of 3,301 elderly people. The Cardiovascular Health Study. Collaborative Research Group. Neuroepidemiology 2000; 19: 30-42.
46. Davatzikos C, Resnick SM. Degenerative age changes in white matter connectivity visualized in vivo using magnetic resonance imaging. Cereb Cortex 2002; 12: 767-771.