An in situ single-pass perfusion model for assessing absorption across the intestinal mucosa of the brushtail possum

New Zealand Veterinary Journal

Volumn 53, Issue 4, 2005, Pages 234-241

  McLeod, B J ^a   Zhang, H ^b   Huang, L ^b   Thompson, E G ^a   Butt, A G ^b   Tucker, I G ^b  

^a INVERMAY AGRICULTURAL CENTRE   (New Zealand)

^b UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Absorption; Brushtail possum; Fluorescein; Intestinal mucosa; LHRH; Permeation enhancer

Indexed keywords

FLUORESCEIN; GONADORELIN;

ANIMAL; AREA UNDER THE CURVE; ARTICLE; BIOLOGICAL MODEL; BLOOD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; INTESTINE ABSORPTION; INTESTINE MUCOSA; MALE; METABOLISM; OPOSSUM; RANDOMIZED CONTROLLED TRIAL;

ANIMALS; AREA UNDER CURVE; FLUORESCEIN; GONADOTROPIN-RELEASING HORMONE; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; MALE; MODELS, BIOLOGICAL; OPOSSUMS;

ANIMALIA; PHALANGERIDAE;

EID: 23244467516     PISSN: 00480169     EISSN: 11760710     Source Type: Journal    
DOI: 10.1080/00480169.2005.36551     Document Type: Article

References (36)

1. Argenzio RA, Henrikson CK, Liacos JA. Restitution of barrier and transport function of porcine colon after acute mucosal injury. American Journal of Physiology 255, G62-G71, 1988
2. Aungst DJ, Rogers NJ, Shefter E. Comparison of nasal, rectal, buccal, sub-lingual and intramuscular insulin efficacy and the effects of a bile salt absorption promoter. Journal of Pharmacology and Experimental Therapeutics 244, 23–7, 1988
3. Bai JP. Colonic delivery of peptide and protein drugs: consideration of intracellular proteolytic enzymes. S.TP Pharma Sciences 5, 30–5, 1995
4. Berger H, Heinrech N, Schafer H, Baeger I, Mehlis B. Gonadotrophin-releasing hormone (GnRH) pharmacokinetics: Peptide hormone pharmacokinetics need clarification. Life Sciences 42, 985–91, 1988
5. Bongard FS, Upton RA, Elings VB, Lewis FR. Digital cutaneous fluorometry: correlation between blood flow and fluorescence. Journal of Vascular Surgery 1, 635–41, 1984
6. Chien YW. Mucosal drug delivery: Potential routes for non-invasive systemic administration. In: Chien YW. Novel Drug Delivery Systems. Pp 197–228. Marcel Dekker, New York, USA, 1992
7. Clout M, Ericksen K. Anatomy of a disastrous success: The brushtail possum as an invasive species. In: Montague TL (ed). The Brushtail Possum: Biology, Impact and Management of an Introduced Marsupial. Pp 1–9. Manaaki Whenua Press, Lincoln, NZ, 2000
8. Damge C, Michel C, Aprahamian M, Couvreur P, Devissaguet JP. Nanocapsules as carriers for oral peptide delivery. Journal of Controlled Release 13, 233–9, 1990
9. Ekdahl M, Smit BL, Money DFL. Tuberculosis in some wild and feral animals in New Zealand. New Zealand Veterinary Journal 18, 44–5, 1970
10. Ellinwood WE, Ronnekleiv OK, Kelly MJ, Resko JA. A new antiserum with conformational specificity for LHRH: Usefulness for radioimmunoassay and immunocytochemistry. Peptides 6, 45–52, 1984
11. Gibaldi M. Biopharmaceutics and Clinical Pharmacokinetics. Lea and Febiger, Philadelphia, USA, 1991
12. Hallbook O, Boeryd B, Lilja I, Sjodahl R. Association between permeability of the colonic wall and azoxymethane-induced cancer of the colon in rats. European Journal of Surgery 158, 491–4, 1992
13. Landaw EM, DiStefano JJ. Multiexponential, multicompartmental and non-compartmental modelling. II. Data analysis and statistical considerations. American Journal of Physiology 246, R665-R667, 1984
14. Langguth P, Merkle HP, Amidon GL. Oral absorption of peptides: the effect of absorption site and enzyme inhibition on the systemic availability of metkephamid. Pharmaceutical Research 11, 528–35, 1994 a
15. Langguth P, Breves G, Stockli A, Merkle HP, Wolffram S. Colonic absorption and bioavailability of the pentapeptide metkephamid in the rat. Pharmaceutical Research 11, 1640–5, 1994 b
16. Langguth P, Bohner V, Heizmann J, Merkle HP, Wolffram S, Amidon GL, Yamashita S. The challenge of proteolytic enzymes in intestinal peptide delivery. Journal of Controlled Release 46, 39–57, 1997
17. Le Ferrec E, Chesne C, Artusson P, Brayden D, Farbre G, Gires P, Guillou F, Rousset M, Rubas W Scarino M-L. In vitro models of intestinal barrier. Alternatives to Laboratory Animals 29, 649–68, 2001
18. Little ECS, Cowan PE. Natural immigration of brushtail possums, Trichosurus vulpecula, into Aroha Island, Kerikeri Inlet, Bay of Islands, New Zealand. New Zealand Journal of Zoology 19, 53–9, 1992
19. Livingstone PG. Tuberculosis in New Zealand- current status and control strategies. Surveillance 19(1), 14–18, 1992
20. Mauricio AC, Slawik M, Heitzmann D, von Hahn T, Warth R, Bleich M, Greger R. Dexoycholic acid (DOC) affects the transport properties of distal colon. Plugers Archives 439, 532–40, 2000
21. McLeod BJ, Thompson EG, Crawford JL, Shackell GH. Successful group-housing of wild-caught brushtail possums (Trichosurus vulpecula). Animal Welfare 7, 47–56, 1997
22. McLeod BJ, McKay G, Thompson EG, Manley TR, Tucker IG. Intra-nasal administration of GnRH to a marsupial- the brushtail possum. Proceedings of the 25th International Symposium of the Controlled Release Society. Pp 663–4, 1998
23. Miyachi Y, Chrambach A, Mecklenberg R, Lipsett MB. Preparation and properties of 125I-LHRH. Endocrinology 92, 1725–30, 1973
24. Payton I. Damage to native Forests. In: Montague TL (ed). The Brushtail Possum: Biology, Impact and Management of an Introduced Marsupial. Pp 111–25. Manaaki Whenua Press, Lincoln, NZ, 2000
25. Powell MF, Stewart T, Otvos L, Urge L, Gaeta FC, Sette A, Arrhenius T, Thomson D, Soda K, Colon SM. Peptide stability in drug development. II. Effect of single amino acid substitution and glycosylation on peptide reactivity in human serum. Pharmaceutical Research 10, 1268–77, 1993
26. Rubinstein A, Tirosh B, Baluom M, Nasser T, David A, Radai R, Gliko-Kabir I, Friedman M. The rationale for peptide delivery to the colon and the potential of polymeric carriers as effective tools. Journal of Controlled Release 46, 59–73, 1997
27. Savina PM, Staubus AH, Gaginella TS, Smith DF. Optimal perfusion rate determined for in situ intestinal absorption studies in rats. Journal of Pharmaceutical Sciences 70, 239–43, 1981
28. Schurgers N, Bijdendijk J, Tukker, JJ, Crommelin DJA. Comparison of four experimental techniques for studying drug absorption kinetics in the anesthetized rat in situ. Journal of Pharmaceutical Sciences 75, 117–9, 1986
29. Stewart BH, Chan OH, Lu RH, Reyner EL, Schmod HL, Hamilton HW, Syeinbaugh BA, Taylor MD. Comparison of intestinal permeabilities determined in vitro and in in situ models: Relationship to absorption in humans. Pharmaceutical Research 12, 693–6, 1995
30. Uchiyama T, Sugiyama T, Quan YS, Ojada N, Fujita T, Muranishi S, Yamamoto A. Enhanced permeability of insulin across rat intestinal membrane by various absorption enhancers; their intestinal mucosal toxicity and absorption-enhancing mechanism of n-lauryl-beta-D-maltopyranoside. Journal of Pharmacy and Pharmacology 51, 1241–50, 1999
31. Wen JY. Barriers to the intestinal absorption of peptides and proteins in the brushtail possum Trichosurus vulpecula. PhD thesis, University of Otago, Dunedin, NZ, 2003
32. Wen JY, Ledger R, Butt AG, McLeod BJ, Davies NM, Tucker IG. Inhibition of proteolysis in luminal extracts from the intestine of the brushtail possum (Trichosurus vulpecula). Journal of Pharmacy and Pharmacology 54, 1365–72, 2002 a
33. Wen JY, Ledger R, McLeod BJ, Davies NM, Butt AG, Tucker IG. Protein and peptide metabolism in the intestine of the brushtail possum (Trichosurus vulpecula). Journal of Comparative Physiology B 172, 553–9, 2002 b
34. Wen JY, Ledger R, McLeod BJ, Davies NM, Butt AG, Tucker IG. Enzymatic degradation of Luteinizing Hormone Releasing Hormone (LHRH) by mucosal homogenates in the intestine of brushtail possum (Trichosurus vulpecula). Life Sciences 71, 3019–30, 2002 c
35. Woodley JF. Enzymatic barriers for GI peptide and protein delivery. Critical Reviews in Therapeutic Drug Carrier Systems 11, 61–95, 1994
36. Wright DE. In: Sutherland G (ed). Advances in the Biological Control of Possums. The Royal Society of New Zealand Miscellaneous Series 56, Wellington, NZ, 1999