Controlled-release matrix tablets of ibuprofen using cellulose ethers and carrageenans: Effect of formulation factors on dissolution rates

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 61, Issue 1-2, 2005, Pages 56-68

  Nerurkar, Jayanti ^a   Jun, H W ^a   Price, J C ^a   Park, M O ^a  

^a UNIVERSITY OF GEORGIA   (United States)

Author keywords

Carrageenan; Controlled release; Hydroxypropyl methylcellulose; Ibuprofen; Tablets; Zero order

Indexed keywords

CARRAGEENAN; CELLULOSE DERIVATIVE; GELCARIN; HYDROXYPROPYLMETHYLCELLULOSE; IBUPROFEN; METHYLCELLULOSE;

ARTICLE; CONTROLLED DRUG RELEASE; DISSOLUTION; DRUG FORMULATION; DRUG RELEASE; HYDRATION; MULTIPLE REGRESSION; PREDICTION; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY; SUSTAINED DRUG RELEASE; TABLET; TABLET COMPRESSION;

CARRAGEENAN; CELLULOSE; DRUG COMPOUNDING; ETHERS; IBUPROFEN; MICROSCOPY, ELECTRON, SCANNING; SOLUBILITY; SURFACE PROPERTIES; TABLETS, ENTERIC-COATED;

EID: 23244466911     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2005.03.003     Document Type: Article

References (33)

1. D.A. Alderman A review of cellulose ethers in hydrophilic matrices for oral controlled-release dosage forms Int. J. Pharm. Tech. Prod. Manuf. 5 3 1984 1 9
2. K. Ranga Rao, K. Padmalatha Devi, and P. Buri Influence of molecular size and water solubility of the solute on its release from swelling and erosion controlled polymeric matrices J. Controlled Release 12 1990 133 141
3. E. Doelker Water-swollen cellulose derivatives in pharmacy N.A. Peppas Hydrogels in Medicine and Pharmacy Polymers vol. II 1987 CRC Press Boca Raton, Florida 115 160
4. T. Durig, and R. Fassihi Guar-based monolithic matrix systems: effect of ionizable and non-ionizable substances and excipients on gel dynamics and release kinetics J. Controlled Release 80 2002 45 56
5. P.J. Cox, K.A. Khan, D.L. Munday, and J. Sujja-areevath Development and evaluation of a multiple-unit oral sustained release dosage form for S(+)-ibuprofen: preparation and release kinetics Int. J. Pharm. 193 1999 73 84
6. M. Hariharan, T.A. Wheatley, and J.C. Price Controlled-release tablet matrices from carrageenans: compression and dissolution studies Pharm. Dev. Technol. 2 4 1997 383 393
7. K.M. Picker The use of carrageenan in mixture with microcrystalline cellulose and its functionality for making tablets Eur. J. Pharm. Biopharm. 48 1999 27 36
8. N.A. Peppas, and R.W. Korsmeyer Dynamically swelling hydrogels in controlled release applications N.A. Peppas Hydrogels in Medicine and Pharmacy Properties and Applications vol. III 1987 CRC Press Boca Raton, Florida 109 135
9. V.K. Gupta, M. Hariharan, T.A. Wheatley, and J.C. Price Controlled-release tablets from carrageenans: effect of formulation, storage and dissolution factors Eur. J. Pharm. Biopharm. 51 2001 241 248
10. L.S.C. Wan, P.W.S. Heng, and L.F. Wong Relationship between swelling and drug release in a hydrophilic matrix Drug Dev. Ind. Pharm. 19 10 1993 1201 1210
11. K.C. Sung, P.R. Nixon, J.W. Skoug, T.R. Ju, P. Gao, E.M. Topp, and M.V. Patel Effect of formulation variables on drug and polymer release from HPMC-based matrix tablets Int. J. Pharm. 142 1996 53 60
12. M.C. Bonferoni, S. Rossi, F. Ferrari, M. Bertoni, G.K. Bolhius, and C. Caramella On the employment of λ carrageenan in a matrix system. III. Optimization of a λ carrageenan - HPMC hydrophilic matrix J. Controlled Release 51 1998 231 239
13. I. Katzhendler, K. Mader, and M. Friedman Structure and hydration properties of hydroxypropyl methylcellulose matrices containing naproxen and naproxen sodium Int. J. Pharm. 200 2000 161 179
14. A.G. Gonzalez Optimization of pharmaceutical formulations based on response-surface experimental designs Int. J. Pharm. 97 1993 149 159
15. M. Efentakis, and M. Vlachou Evaluation of high molecular weight poly(oxyethylene) (polyox) polymer: studies of flow properties and release rates of furosemide and captopril from controlled-release hard gelatin capsules Pharm. Dev. Technol. 5 3 2000 339 346
16. R.L. Carr Evaluating flow properties of solids Chem. Eng. 72 1965 163 168
17. A. Nokhodchi, M.H. Rubinstein, and J.L. Ford The effect of particle size and viscosity grade on the compaction properties of hydroxypropylmethycellulose 2208 Int. J. Pharm. 126 1995 189 197
18. N.A. Peppas Analysis of Fickian and non-Fickian drug release from polymers Pharm. Acta Helv. 60 4 1985 110 111
19. P.L. Ritger, and N.A. Peppas A simple equation for description of solute release II. Fickian and anomalous release from swellable devices J. Controlled Release 5 1987 37 42
20. H. Lapidus, and N.G. Lordi Some factors affecting the release of a water-soluble drug from a compressed hydrophilic matrix J. Pharm. Sci. 55 1966 840 843
21. H. Lapidus, and N.G. Lordi Drug release from compressed hydrophilic matrices J. Pharm. Sci. 57 1968 1292 1301
22. N.L. Rosario, and E.S. Ghaly Matrices of water-soluble drug using natural polymer and direct compression method Drug Dev. Ind. Pharm. 28 8 2002 975 988
23. N.K. Ebube, and A.B. Jones Sustained release of acetaminophen from a heterogeneous mixture of two hydrophilic non-ionic cellulose ether polymers Int. J. Pharm. 272 2004 19 27
24. J.R. Cardinal Drug release from matrix devices J.M. Anderson S.W. Kim Recent Advances in Drug Delivery Systems 1984 Plenum Press New York 229 248
25. T.J. Roseman, and W.I. Higuchi Release of medroxyprogesterone acetate from silicone polymer J. Pharm. Sci. 59 1970 353 357
26. R. Bettini, P.L. Catellani, P. Santi, G. Massimo, N.A. Peppas, and P. Colombo Translocation of drug particles in HPMC matrix gel layer: effect of drug solubility and influence on release rate J. Controlled Release 70 2001 383 391
27. S.M. Samani, H. Montaseri, and A. Kazemi The effect of polymer blends on release profiles of diclofenac sodium from matrices Eur. J. Pharm. Biopharm. 55 2003 351 355
28. Y.M. Rao, J.K. Veni, and G. Jayasagar Formulation and evaluation of diclofenac sodium using hydrophilic matrices Drug Dev. Ind. Pharm. 27 8 2001 759 766
29. N.K. Ebube, A.H. Hikal, C.M. Wyandt, D.C. Beer, L.G. Miller, and A.B. Jones Effect of drug, formulation and process variables on granulation and compaction characteristics of heterogeneous matrices. Part I: HPMC and HPC systems Int. J. Pharm. 156 1997 49 57
30. D.S. Roy, and B.D. Rohera Comparative evaluation of rate of hydration and matrix erosion of HEC and HPC and study of drug release from their matrices Eur. J. Pharm. Sci. 16 2002 193 199
31. M.L. Vueba, L.A.E. Batista de Carvalho, F. Veiga, J.J. Sousa, and M.E. Pina Influence of cellulose ether polymers on ketoprofen release from hydrophilic matrix tablets Eur. J. Pharm. Biopharm. 58 2004 51 59
32. M.C. Alvarez, A.M. Cuitino, M.J. Roddy, and N.G. Lordi Comparison of the microstructure and mechanical behavior of visco-plastic and visco-elastic solids during compaction Pharm. Sci. 1S 1998 179
33. F. Ravenelle, R.H. Marchessault, A. Legare, and M.D. Buschmann Mechanical properties and structure of swollen crosslinked high amylose starch tablets Carbohydr. Polym. 47 2002 259 266