Older liver graft transplantation, cholestasis and synthetic graft function

Transplant International

Volumn 18, Issue 6, 2005, Pages 709-715

  Borchert, Dietmar ^a,b   Glanemann, Matthias ^a   Mogl, Martina ^a   Langrehr, Jan M ^a   Neuhaus, Peter ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

Cadaveric donors; Donation; Expanded donor pool; Outcome; Selection criteria

Indexed keywords

AGED; ARTICLE; CHOLESTASIS; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FOLLOW UP; GRAFT REJECTION; GRAFT SURVIVAL; HUMAN; LIVER GRAFT; MALE; ORGAN DONOR; PRIORITY JOURNAL; PROTEIN SYNTHESIS; TREATMENT OUTCOME; ADULT; AGE; DONOR; LIVER REGENERATION; LIVER TRANSPLANTATION; MIDDLE AGED; RETROSPECTIVE STUDY;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; CHOLESTASIS; FEMALE; GRAFT SURVIVAL; HUMANS; LIVER REGENERATION; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; PROTEIN BIOSYNTHESIS; RETROSPECTIVE STUDIES; TISSUE DONORS;

EID: 23244463739     PISSN: 09340874     EISSN: 14322277     Source Type: Journal    
DOI: 10.1111/j.1432-2277.2005.00128.x     Document Type: Article

References (30)

1. Mimeault R, Grant D, Ghent C, Duff J, Wall W. Analysis of donor and recipient variables and early graft function after orthotopic liver transplantation. Transplant Proc 1989; 21: 3355.
2. Levy MF, Somasundar PS, Jennings LW, et al. The elderly liver transplant recipient: a call for caution. Ann Surg 2001; 233: 107.
3. Keswani RN, Aijaz A, Emmet BK. Older age and liver transplantation: a review. Liver Transpl 2004; 10: 957.
4. Zeeh J, Platt D. The aging liver: structural and functional changes and their consequences for drug treatment in old age. Gerontology 2002; 48: 121.
5. Adam R, McMaster P, O'Grady JG, et al. Evolution of liver transplantation in Europe: report of the European Liver Transplant Registry. Liver Transpl 2003; 9: 1231.
6. Cescon M, Grazi GL, Ercolani G, et al. Long-term survival of recipients of liver grafts from donors older than 80 years: is it achievable? Liver Transpl 2003; 9: 1174.
7. Beltempo P, Nardo B, Montalti R, Bertelli R, Puviani L, Cavallari A. Octogenarian Livers Successful Transplanted in Patients with Fulminant Hepatic Failure. Poster Presentation International Congress of the Transplantation Society. Vienna, Austria: The Transplantation Society, 2004.
8. Neuhaus P, Blumhardt G, Bechstein WO, Steffen R, Platz KP, Keck H. Technique and results of biliary reconstruction using side-to-side choledochostomy in 300 orthotopic liver transplants. Ann Surg 1994; 219: 426.
9. Neuhaus P, Bechstein WO, Lefebre B, Blumhardt G, Slama K. Effect of aprotinin on intraoperative bleeding and fibrinolysis in liver transplantation. Lancet 1989; 2: 924
10. Glanemann M, Langrehr J, Kaisers U, et al. Postoperative tracheal extubation after orthotopic liver transplantation. Acta Anaesthesiol Scand 2001; 45: 333.
11. Verran DJ, Gurkan A, Dilworth P, et al. Inferior liver allograft survival from cadaveric donors >50 years of age? Clin Transplant 2001; 15: 106.
12. Glanemann M, Langrehr JM, Stange BJ, et al. Clinical implications of hepatic preservation injury after adult liver transplantation. Am J Transplant 2003; 3: 1003.
13. Washburn WK, Johnson LB, Lewis WD, Jenkins RL. Graft function and outcome of older (≥60 years) donor livers. Transplantation 1996; 61: 1062.
14. Yersiz H, Shaked A, Olthoff K, et al. Correlation between donor age and the pattern of liver graft recovery after transplantation. Transplantation 1995; 60: 790.
15. Abraham SC, Furth EE. Receiver operating characteristic analysis of serum chemical parameters as tests of liver transplant rejection and correlation with histology. Transplantation 1995; 59: 740.
16. Sapey T, Mendler MH, Guyader D, et al. Respective value of alkaline phosphatase, gamma-glutamyl transpeptidase and 5′ nucleotidase serum activity in the diagnosis of cholestasis: a prospective study of 80 patients. J Clin Gastroenterol 2000; 30: 259.
17. Anantharaju A, Feller A, Chedid A. Aging liver: A review. Gerontology 2002; 48: 343.
18. Ikegami T, Nishizaki T, Yanaga K, et al. The impact of donor age on living donor liver transplantation. Transplantation 2000; 70: 1703.
19. Kimura F, Miyazaki M, Suwa T, Kakizaki S. Reduction of hepatic acute phase response after partial hepatectomy in elderly patients. Res Exp Med (Berl) 1996; 196: 281.
20. Tsukamoto I, Nakata R, Kojo S. Effect of ageing on rat liver regeneration after partial hepatectomy. Biochem Mol Biol Int 1993; 30: 773.
21. Verran D, Kusyk T, Painter D, et al. Clinical experience gained from the use of 120 steatotic donor livers for orthotopic liver transplantation. Liver Transpl 2003; 9: 500.
22. Salizzoni M, Franchello A, Zamboni F, et al. Marginal grafts: finding the correct treatment for fatty livers. Transpl Int 2003; 16: 486.
23. Rull R, Vidal O, Momblan D, et al. Evaluation of potential liver donors: limits imposed by donor variables in liver transplantation. Liver Transpl 2003; 9: 389.
24. Jimenez RC, Moreno GE, Colina RF, et al. Use of octogenarian livers safely expands the donor pool. Transplantation 1999; 68: 572.
25. Emre S, Schwartz ME, Altaca G, et al. Safe use of hepatic allografts from donors older than 70 years. Transplantation 1996; 62: 62.
26. Makowka L, Gordon RD, Todo S, et al. Analysis of donor criteria for the prediction of outcome in clinical liver transplantation. Transplant Proc 1987; 19(Pt 3): 2378.
27. Briceno J, Marchal T, Padillo J, Solorzano G, Pera C. Influence of marginal donors on liver preservation injury. Transplantation 2002; 74: 522.
28. Hoofnagle JH, Lombardero M, Zetterman RK, et al. Donor age and outcome of liver transplantation. Hepatology 1996; 24: 89.
29. Ploeg RJ, D'Alessandro AM, Knechtle SJ, et al. Risk factors for primary dysfunction after liver transplantation - a multivariate analysis. Transplantation 1993; 55: 807.
30. Alexander JW, Zola JC. Expanding the donor pool: use of marginal donors for solid organ transplantation. Clin Transplant 1996; 10(Pt 1): 1.