Measurement of bile acid CoA esters by high-performance liquid chromatography-electrospray ionisation tandem mass spectrometry (HPLC-ESI-MS/MS)

Journal of Mass Spectrometry

Volumn 40, Issue 7, 2005, Pages 882-889

  Gan Schreier, H ^a   Okun, J G ^a   Kohlmueller, D ^a   Langhans, C D ^a   Peters, V ^a   Ten Brink, H J ^b   Verhoeven, N M ^b   Jakobs, C ^b   Voelkl, A ^c   Hoffmann, G F ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Bile acids; CoA esters; ESI MS MS; HPLC; Peroxisomes

Indexed keywords

ESTERS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY;

ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

ORGANIC ACIDS;

BILE ACID; DEUTERIUM; ESTER;

ARTICLE; BILE ACID SYNTHESIS; BIOSYNTHESIS; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOTOPE LABELING; MASS SPECTROMETRY; MEASUREMENT; PRIORITY JOURNAL; SYNTHESIS; TANDEM MASS SPECTROMETRY; ZELLWEGER SYNDROME;

ACYL COENZYME A; BILE ACIDS AND SALTS; CALIBRATION; CHOLESTANOLS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COENZYME A; ESTERS; MOLECULAR STRUCTURE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 23244445357     PISSN: 10765174     EISSN: None     Source Type: Journal    
DOI: 10.1002/jms.864     Document Type: Article

References (18)

1. Danielsson H. Mechanism of bile acid biosynthesis. The Bile Acids, Vol 2. Physiology and Metabolism. Plenum Press: New York, 1973; 1.
2. Bjorkhem I. Mechanism of bile acid biosynthesis in mammalian liver. Sterols and Bile Acids. Elsevier Science: Amsterdam, The Netherlands. 1985; 231.
3. Pedersen JI, Gustafsson J. Conversion of 3α,7α,12α- trihydroxy-5β-cholestanoic acid into cholic acid by rat liver peroxisomes. FEBS Lett. 1980; 121: 345.
4. Bjorkhem I, Kase F, Pedersen JI. Mechanism of peroxisomal 24-hydroxylation of 3α,7α,12α-trihydroxy-5β-cholestanoic acid in rat liver. Biochem. Biophys. Acta 1984; 796: 142.
5. Kase F, Bjorkhem I, Pedersen JI. Formation of cholic acid from 3α,7α,12α-trihydroxy-5β-cholestanoic acid by rat liver peroxisomes. J. Lipid Res. 1983; 24: 1560.
6. Kase BF, Pedersen JI, Strandvik B, Bjorkhem I. In vivo and in vitro studies on formation of bile acids in patients with Zellweger syndrome. J. Clin. Invest. 1985; 76: 2393.
7. Russell DW, Setchell KDR. Bile acid biosynthesis. Biochemistry 1992; 31: 4737.
8. Vessey DA, Crissey MH, Zakim D. Characterization of microsomal choloyl-coenzyme a synthetase. Biochem. J. 1977; 163: 181.
9. Perwaiz S, Tuchweber B, Mignault D, Gilat T, Yousef IM. Determination of bile acid in biological fluids by liquid chromatography-electrospray tandem mass spectrometry. J. Lipid Res. 2001; 42: 114.
10. Torchia EC, Labonté ED, Agellon LB. Separation and quantitation of bile acids using an isocratic solvent system for high performance liquid chromatography coupled to an evaporative light scattering detector. Anal. Biochem. 2001; 298: 293.
11. Mills AK, Mushtaq I, Johnson AW, Whitfield PD, Clayton PT. A method for the quantitation of conjugated bile acids in dried blood spots using electrospray ionization-mass spectrometry. Pediatr. Res. 1998; 43: 361.
12. Johnson DW, ten Brink HJ, Schuit RC, Jakobs C. Rapid and quantitative analysis of unconjugated C27 bile acids in plasma and blood samples by tandem mass spectrometry. J. Lipid Res. 2001; 42: 9.
13. 27-bile acid CoA esters by liquid chromatography and ist application to the study of the stereo specifities of D- and L-bifunctional proteins in bile acid biosynthesis. Anal. Chim. Acta 1998; 365: 249.
14. Reddy JK, Mannaerts GP. Peroxisomal lipid metabolism. Annu. Rev. Nutr. 1994; 14: 343.
15. Deakin H, Ord MG, Stocken LA. Glucose 6-phosphate-dehydrogenase activity and thiol content of thymus nuclei from control and X-irradiated rats. Biochem. J. 1963; 89: 296.
16. Voelkl A, Fahimi HD. Isolation and characterization of peroxisomes from the liver of normal untreated rats. Eur. J. Biochem. 1985; 149: 257.
17. Wanders RJ, Schutgens RB, Barth PG. Peroxisomal disorders: a review. J. Neuropathol. Exp. Neurol. 1995; 54: 726.
18. Bjorkhem I. Inborn errors of metabolism with consequences for bile acid biosynthesis. A minireview. Scand. J. Gastroenterol. 1994; 204: 68.