메뉴 건너뛰기




Volumn 1, Issue 1, 2005, Pages 23-30

Cancer and immunosuppression: Pro- and antitumoral effects of immunosuppressive drugs;Cancers et immunosuppression: Effet pro- et antitumoral des traitements immunosuppresseurs

Author keywords

Calcineurin inhibitors; Cancer; Carcinogenesis; Immunosuppressive drugs; mTOR inhibitors; Organ transplantation

Indexed keywords

AZATHIOPRINE; CALCINEURIN INHIBITOR; CYCLOSPORIN; EVEROLIMUS; INTERLEUKIN 6; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; RAPAMYCIN; STEROID; TACROLIMUS;

EID: 23244444096     PISSN: 17697255     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nephro.2005.01.003     Document Type: Short Survey
Times cited : (10)

References (45)
  • 1
    • 0034871856 scopus 로고    scopus 로고
    • Causes of death after renal transplantation
    • Briggs JD. Causes of death after renal transplantation. Nephrol Dial Transplant 2001;16:1545-9.
    • (2001) Nephrol Dial Transplant , vol.16 , pp. 1545-1549
    • Briggs, J.D.1
  • 2
    • 0033853911 scopus 로고    scopus 로고
    • Post-transplant malignancy: The role of immunosuppression
    • Penn I. Post-transplant malignancy: the role of immunosuppression. Drug Saf 2000;23:101-13.
    • (2000) Drug Saf , vol.23 , pp. 101-113
    • Penn, I.1
  • 3
    • 0034113459 scopus 로고    scopus 로고
    • Cancers in renal transplant recipients
    • Penn I. Cancers in renal transplant recipients. Adv Ren Replace Ther 2000;7:147-56.
    • (2000) Adv Ren Replace Ther , vol.7 , pp. 147-156
    • Penn, I.1
  • 4
    • 0037464506 scopus 로고    scopus 로고
    • Skin cancers after organ transplantation
    • Euvrard S, Kanitakis J, Claudy A. Skin cancers after organ transplantation. N Engl J Med 2003;348(17):1681-91.
    • (2003) N Engl J Med , vol.348 , Issue.17 , pp. 1681-1691
    • Euvrard, S.1    Kanitakis, J.2    Claudy, A.3
  • 5
  • 6
    • 0036440599 scopus 로고    scopus 로고
    • Non-melanoma skin cancer risk in the Queensland renal transplant population
    • Ramsay HM, Fryer AA, Hawley CM, Smith AG, Harden PN. Non-melanoma skin cancer risk in the Queensland renal transplant population. Br J Dermatol 2002;147(5):950-6.
    • (2002) Br J Dermatol , vol.147 , Issue.5 , pp. 950-956
    • Ramsay, H.M.1    Fryer, A.A.2    Hawley, C.M.3    Smith, A.G.4    Harden, P.N.5
  • 7
    • 0030961527 scopus 로고    scopus 로고
    • Skin tumours posttransplantation: A retrospective analysis of 28 years' experience at a single centre
    • Webb MC, Compton F, Andrews PA, Koffman CG. Skin tumours posttransplantation: a retrospective analysis of 28 years' experience at a single centre. Transplant Proc 1997;29(1-2):828-30.
    • (1997) Transplant Proc , vol.29 , Issue.1-2 , pp. 828-830
    • Webb, M.C.1    Compton, F.2    Andrews, P.A.3    Koffman, C.G.4
  • 8
    • 0001803227 scopus 로고
    • Diseases of whites cells, lymph nodes and spleen
    • Cotran VK RS, Robbins SC, editors. Philadelphia: Saunders WB
    • Cotran RS. Diseases of whites cells, lymph nodes and spleen. In: Cotran VK RS, Robbins SC, editors. Pathologic basis of disease. Philadelphia: Saunders WB; 1994. p. 629-47.
    • (1994) Pathologic Basis of Disease , pp. 629-647
    • Cotran, R.S.1
  • 9
    • 0032572809 scopus 로고    scopus 로고
    • Long-term comparison of tacrolimus versus cyclosporine in liver transplantation
    • The US FK Study Group
    • Wiesner RH. Long-term comparison of tacrolimus versus cyclosporine in liver transplantation. The US FK Study Group. Transplantation 1998;66(4):493-9.
    • (1998) Transplantation , vol.66 , Issue.4 , pp. 493-499
    • Wiesner, R.H.1
  • 10
    • 0030809592 scopus 로고    scopus 로고
    • De novo malignancies after liver transplantation using tacrolimus-based protocols or cyclosporine-based quadruple immunosuppression with an interleukin-2 receptor antibody or antithymocyte giobulin
    • Jonas S, Rayes N, Neumann U, Neuhaus R, Bechstein WO, Guckelberger O, et al. De novo malignancies after liver transplantation using tacrolimus-based protocols or cyclosporine-based quadruple immunosuppression with an interleukin-2 receptor antibody or antithymocyte giobulin. Cancer 1997;80(6):1141-50.
    • (1997) Cancer , vol.80 , Issue.6 , pp. 1141-1150
    • Jonas, S.1    Rayes, N.2    Neumann, U.3    Neuhaus, R.4    Bechstein, W.O.5    Guckelberger, O.6
  • 11
    • 0026062060 scopus 로고
    • Apoptosis: Mode of cell death induced in T cell leukemia lines by dexamethasone and other agents
    • Bansal N, Houle A, Melnykowych G. Apoptosis: mode of cell death induced in T cell leukemia lines by dexamethasone and other agents. FASEB J 1991;5(2):211-6.
    • (1991) FASEB J , vol.5 , Issue.2 , pp. 211-216
    • Bansal, N.1    Houle, A.2    Melnykowych, G.3
  • 12
    • 0037079310 scopus 로고    scopus 로고
    • Effects of corticosteroid use on treatment of solid tumours
    • Rutz HP. Effects of corticosteroid use on treatment of solid tumours. Lancet 2002;360(9349):1969-70.
    • (2002) Lancet , vol.360 , Issue.9349 , pp. 1969-1970
    • Rutz, H.P.1
  • 13
    • 0027169368 scopus 로고
    • Modulation of multidrug resistance gene expression by dexamethasone in cultured hepatoma cells
    • Zhao JY, Ikeguchi M, Eckersberg T, Kuo MT. Modulation of multidrug resistance gene expression by dexamethasone in cultured hepatoma cells. Endocrinology 1993;133(2): 521-8.
    • (1993) Endocrinology , vol.133 , Issue.2 , pp. 521-528
    • Zhao, J.Y.1    Ikeguchi, M.2    Eckersberg, T.3    Kuo, M.T.4
  • 14
    • 0032563826 scopus 로고    scopus 로고
    • Dexamethasone-mediated protection from drug cytotoxicity: Association with p21WAF1/CIP1 protein accumulation?
    • Naumann U, Durka S, Weller M. Dexamethasone-mediated protection from drug cytotoxicity: association with p21WAF1/CIP1 protein accumulation? Oncogene 1998; 17(12):1567-75.
    • (1998) Oncogene , vol.17 , Issue.12 , pp. 1567-1575
    • Naumann, U.1    Durka, S.2    Weller, M.3
  • 15
    • 0031110584 scopus 로고    scopus 로고
    • Induction of vascular endothelial growth factor by platelet-activating factor and platelet-derived growth factor is downregulated by corticosteroids
    • Nauck M, Roth M, Tamm M, Eickelberg O, Wieland H, Stulz P, et al. Induction of vascular endothelial growth factor by platelet-activating factor and platelet-derived growth factor is downregulated by corticosteroids. Am J Respir Cell Mol Biol 1997;16(4):398-406.
    • (1997) Am J Respir Cell Mol Biol , vol.16 , Issue.4 , pp. 398-406
    • Nauck, M.1    Roth, M.2    Tamm, M.3    Eickelberg, O.4    Wieland, H.5    Stulz, P.6
  • 16
    • 0025034447 scopus 로고
    • Azathioprine metabolism: Pharmacokinetics of 6-mercaptopurine, 6-thiouric acid and 6-thioguanine nucleotides in renal transplant patients
    • Chan GL, Erdmann GR, Gruber SA, Matas AJ, Canafax DM. Azathioprine metabolism: pharmacokinetics of 6-mercaptopurine, 6-thiouric acid and 6-thioguanine nucleotides in renal transplant patients. J Clin Pharmacol 1990;30(4): 358-63.
    • (1990) J Clin Pharmacol , vol.30 , Issue.4 , pp. 358-363
    • Chan, G.L.1    Erdmann, G.R.2    Gruber, S.A.3    Matas, A.J.4    Canafax, D.M.5
  • 17
    • 0022004061 scopus 로고
    • Incidence of cancer in rheumatoid arthritis and other disorders after immunosuppressive treatment
    • Kinlen LJ. Incidence of cancer in rheumatoid arthritis and other disorders after immunosuppressive treatment. Am J Med 1985;78(1A):44-9.
    • (1985) Am J Med , vol.78 , Issue.1 A , pp. 44-49
    • Kinlen, L.J.1
  • 18
    • 0026566048 scopus 로고
    • Skin cancer after renal transplantation: The causal role of azathioprine
    • Taylor AE, Shuster S. Skin cancer after renal transplantation: the causal role of azathioprine. Acta Derm Venereol 1992;72(2):115-9.
    • (1992) Acta Derm Venereol , vol.72 , Issue.2 , pp. 115-119
    • Taylor, A.E.1    Shuster, S.2
  • 19
    • 0023114280 scopus 로고
    • Performance of short term tests for detection of human carcinogens
    • Kuroki T, Matsushima T. Performance of short term tests for detection of human carcinogens. Mutagenesis 1987; 2(1):33-7.
    • (1987) Mutagenesis , vol.2 , Issue.1 , pp. 33-37
    • Kuroki, T.1    Matsushima, T.2
  • 20
    • 0025192883 scopus 로고
    • Synergistic effects of azathioprine and ultraviolet light detected by sister chromatid exchange analysis
    • Dalton A, Curtis D, Harrington CI. Synergistic effects of azathioprine and ultraviolet light detected by sister chromatid exchange analysis. Cancer Genet Cytogenet 1990; 45(1):93-9.
    • (1990) Cancer Genet Cytogenet , vol.45 , Issue.1 , pp. 93-99
    • Dalton, A.1    Curtis, D.2    Harrington, C.I.3
  • 21
    • 0022354811 scopus 로고
    • Skin cancer in renal transplant recipients is associated with increased concentrations of 6-thioguanine nucleotide in red blood cells
    • Lennard L, Thomas S, Harrington C, Maddocks J. Skin cancer in renal transplant recipients is associated with increased concentrations of 6-thioguanine nucleotide in red blood cells. Br J Dermatol 1985;113(6):723-9.
    • (1985) Br J Dermatol , vol.113 , Issue.6 , pp. 723-729
    • Lennard, L.1    Thomas, S.2    Harrington, C.3    Maddocks, J.4
  • 22
    • 0023579265 scopus 로고
    • Scheduled and unscheduled DNA synthesis in epidermal cells of hairless mice treated with immunosuppressive drugs and UVB-UVA irradiation
    • Kelly GE, Meikle W, Sheil AG. Scheduled and unscheduled DNA synthesis in epidermal cells of hairless mice treated with immunosuppressive drugs and UVB-UVA irradiation. Br J Dermatol 1987;117(4):429-40.
    • (1987) Br J Dermatol , vol.117 , Issue.4 , pp. 429-440
    • Kelly, G.E.1    Meikle, W.2    Sheil, A.G.3
  • 24
    • 0029939829 scopus 로고    scopus 로고
    • Interactions involving cyclosporine A, interleukin-6, and Epstein-Barr virus lead to the promotion of B-cell lymphoproliferative disease
    • Tanner JE, Alfieri C. Interactions involving cyclosporine A, interleukin-6, and Epstein-Barr virus lead to the promotion of B-cell lymphoproliferative disease. Leuk Lymphoma 1996;21(5-6):379-90.
    • (1996) Leuk Lymphoma , vol.21 , Issue.5-6 , pp. 379-390
    • Tanner, J.E.1    Alfieri, C.2
  • 25
    • 0033194959 scopus 로고    scopus 로고
    • Cyclosporin A inhibits Ca2+-mediated upregulation of the DNA repair enzyme DNA polymerase beta in human peripheral blood mononuclear cells
    • Ahlers C, Kreideweiss S, Nordheim A, Ruhlmann A. Cyclosporin A inhibits Ca2+-mediated upregulation of the DNA repair enzyme DNA polymerase beta in human peripheral blood mononuclear cells. Eur J Biochem 1999;264(3): 952-9.
    • (1999) Eur J Biochem , vol.264 , Issue.3 , pp. 952-959
    • Ahlers, C.1    Kreideweiss, S.2    Nordheim, A.3    Ruhlmann, A.4
  • 26
    • 0033545299 scopus 로고    scopus 로고
    • Cyclosporine induces cancer progression by a cell-autonomous mechanism
    • Hojo M, Morimoto T, Maluccio M, Asano T, Morimoto K, Lagman M, et al. Cyclosporine induces cancer progression by a cell-autonomous mechanism. Nature 1999;397(6719): 530-4.
    • (1999) Nature , vol.397 , Issue.6719 , pp. 530-534
    • Hojo, M.1    Morimoto, T.2    Maluccio, M.3    Asano, T.4    Morimoto, K.5    Lagman, M.6
  • 27
    • 0032426222 scopus 로고    scopus 로고
    • Rapid adhesion and spread of non-adherent colon cancer color201 cells induced by the protein kinase inhibitors, K252a and KT5720 and suppression of the adhesion by the immunosuppressants FK506 and cyclosporin A
    • Mohri T, Kameshita I, Suzuki S, Hioki K, Tokunaga R, Takatani S. Rapid adhesion and spread of non-adherent colon cancer color201 cells induced by the protein kinase inhibitors, K252a and KT5720 and suppression of the adhesion by the immunosuppressants FK506 and cyclosporin A. Cell Struct Funct 1998;23(5):255-64.
    • (1998) Cell Struct Funct , vol.23 , Issue.5 , pp. 255-264
    • Mohri, T.1    Kameshita, I.2    Suzuki, S.3    Hioki, K.4    Tokunaga, R.5    Takatani, S.6
  • 28
    • 0032525063 scopus 로고    scopus 로고
    • Effect of cyclosporine and tacrolimus on the growth of Epstein-Barr virus-transformed B-cell lines
    • Beatty PR, Krams SM, Esquivel CO, Martinez OM. Effect of cyclosporine and tacrolimus on the growth of Epstein-Barr virus-transformed B-cell lines. Transplantation 1998;65(9): 1248-55.
    • (1998) Transplantation , vol.65 , Issue.9 , pp. 1248-1255
    • Beatty, P.R.1    Krams, S.M.2    Esquivel, C.O.3    Martinez, O.M.4
  • 29
    • 0033746534 scopus 로고    scopus 로고
    • Cyclosporin a inhibits chromium(VI)-induced apoptosis and mitochondrial cytochrome c release and restores clonogenic survival in CHO cells
    • Pritchard DE, Singh J, Carlisle DL, Patierno SR. Cyclosporin A inhibits chromium(VI)-induced apoptosis and mitochondrial cytochrome c release and restores clonogenic survival in CHO cells. Carcinogenesis 2000;21(11):2027-33.
    • (2000) Carcinogenesis , vol.21 , Issue.11 , pp. 2027-2033
    • Pritchard, D.E.1    Singh, J.2    Carlisle, D.L.3    Patierno, S.R.4
  • 30
    • 0344766073 scopus 로고    scopus 로고
    • Protective effect of cyclosporin A and FK506 from nitric oxide-dependent apoptosis in activated macrophages
    • Hortelano S, Lopez-Collazo E, Bosca L. Protective effect of cyclosporin A and FK506 from nitric oxide-dependent apoptosis in activated macrophages. Br J Pharmacol 1999; 126(5):1139-46.
    • (1999) Br J Pharmacol , vol.126 , Issue.5 , pp. 1139-1146
    • Hortelano, S.1    Lopez-Collazo, E.2    Bosca, L.3
  • 31
    • 0034700967 scopus 로고    scopus 로고
    • Drug selectivity is determined by coupling across the NAD+ site of IMP deshydrogenase
    • Digits JA, Hedstrom L. Drug selectivity is determined by coupling across the NAD+ site of IMP deshydrogenase. Biochemistry 2000;39(7):1771-7.
    • (2000) Biochemistry , vol.39 , Issue.7 , pp. 1771-1777
    • Digits, J.A.1    Hedstrom, L.2
  • 32
    • 0032775451 scopus 로고    scopus 로고
    • Nucleoside and non-nucleoside IMP dehydrogenase inhibitors as antitumor and antiviral agents
    • Franchetti P, Grifantini M. Nucleoside and non-nucleoside IMP dehydrogenase inhibitors as antitumor and antiviral agents. Curr Med Chem 1999;6(7):599-614.
    • (1999) Curr Med Chem , vol.6 , Issue.7 , pp. 599-614
    • Franchetti, P.1    Grifantini, M.2
  • 33
    • 0021824479 scopus 로고
    • Biochemical and antitumor activity of tiazofurin and its selenium analog (2-beta-D-ribofuranosyl-4-selenazolecarboxamide)
    • Boritzki TJ, Berry DA, Besserer JA, Cook PD, Fry DW, Leopold WR, et al. Biochemical and antitumor activity of tiazofurin and its selenium analog (2-beta-D-ribofuranosyl-4-selenazolecarboxamide). Biochem Pharmacol 1985; 34(7):1109-14.
    • (1985) Biochem Pharmacol , vol.34 , Issue.7 , pp. 1109-1114
    • Boritzki, T.J.1    Berry, D.A.2    Besserer, J.A.3    Cook, P.D.4    Fry, D.W.5    Leopold, W.R.6
  • 34
    • 0022995588 scopus 로고
    • Studies on the mechanism of action of tiazofurin (2-beta-D- ribofuranosylthiazole-4-carboxamide). VI. Biochemical and pharmacological studies on the degradation of thiazole-4-carboxamide adenine dinucleotide (TAD)
    • Ahluwalia GS, Cooney DA, Marquez VE, Jayaram HN, Johns DG. Studies on the mechanism of action of tiazofurin (2-beta-D-ribofuranosylthiazole-4- carboxamide). VI. Biochemical and pharmacological studies on the degradation of thiazole-4-carboxamide adenine dinucleotide (TAD). Biochem Pharmacol 1986;35(21):3783-90.
    • (1986) Biochem Pharmacol , vol.35 , Issue.21 , pp. 3783-3790
    • Ahluwalia, G.S.1    Cooney, D.A.2    Marquez, V.E.3    Jayaram, H.N.4    Johns, D.G.5
  • 35
    • 0028181387 scopus 로고
    • Anti-tumor activity of mycophenolate mofetil against human and mouse tumors in vivo
    • Tressler RJ, Garvin LJ, Slate DL. Anti-tumor activity of mycophenolate mofetil against human and mouse tumors in vivo. Int J Cancer 1994;57(4):568-73.
    • (1994) Int J Cancer , vol.57 , Issue.4 , pp. 568-573
    • Tressler, R.J.1    Garvin, L.J.2    Slate, D.L.3
  • 36
    • 0016713286 scopus 로고
    • Rapamycin (AY-22, 989) a new antifungal antibiotic. II. Fermentation, isolation and characterization
    • Sehgal SN, Baker H, Vezina C. Rapamycin (AY-22, 989) a new antifungal antibiotic. II. Fermentation, isolation and characterization. J Antibiot (Tokyo) 1975;28(10):727-32.
    • (1975) J Antibiot (Tokyo) , vol.28 , Issue.10 , pp. 727-732
    • Sehgal, S.N.1    Baker, H.2    Vezina, C.3
  • 37
    • 0036707338 scopus 로고    scopus 로고
    • CCI-779 Wyeth
    • Elit L. CCI-779 Wyeth. Curr Opin Investig Drugs 2002;3(8): 1249-53.
    • (2002) Curr Opin Investig Drugs , vol.3 , Issue.8 , pp. 1249-1253
    • Elit, L.1
  • 39
    • 0034722888 scopus 로고    scopus 로고
    • The rapamycin-sensitive signal transduction pathway as a target for cancer therapy
    • Hidalgo M, Rowinsky EK. The rapamycin-sensitive signal transduction pathway as a target for cancer therapy. Oncogene 2000;19(56):6680-6.
    • (2000) Oncogene , vol.19 , Issue.56 , pp. 6680-6686
    • Hidalgo, M.1    Rowinsky, E.K.2
  • 40
    • 0036174289 scopus 로고    scopus 로고
    • Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: Involvement of vascular endothelial growth factor
    • Guba M, von Breitenbuch P, Steinbauer M, Koehl G, Flegel S, Hornung M, et al. Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor. Nat Med 2002; 8(2):128-35.
    • (2002) Nat Med , vol.8 , Issue.2 , pp. 128-135
    • Guba, M.1    Von Breitenbuch, P.2    Steinbauer, M.3    Koehl, G.4    Flegel, S.5    Hornung, M.6
  • 41
    • 0036888908 scopus 로고    scopus 로고
    • Rapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, onogene-transformed, and human cancer cells
    • Law BK, Chytil A, Dumont N, Hamiton EG, Waltner-Law ME, Aakre ME, et al. Rapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, onogene-transformed, and human cancer cells. Mol Cell Biol 2002;22(23):8184-98.
    • (2002) Mol Cell Biol , vol.22 , Issue.23 , pp. 8184-8198
    • Law, B.K.1    Chytil, A.2    Dumont, N.3    Hamiton, E.G.4    Waltner-Law, M.E.5    Aakre, M.E.6
  • 42
    • 0037182139 scopus 로고    scopus 로고
    • Rapamycin blocks tumor progression: Unlinking immunosuppression from antitumor efficacy
    • Luan FL, Hojo M, Mallucio M, Yamaji K, Suthanthiran M. Rapamycin blocks tumor progression: unlinking immunosuppression from antitumor efficacy. Transplantation 2002;73(10):1565-72.
    • (2002) Transplantation , vol.73 , Issue.10 , pp. 1565-1572
    • Luan, F.L.1    Hojo, M.2    Mallucio, M.3    Yamaji, K.4    Suthanthiran, M.5
  • 43
    • 0028925744 scopus 로고
    • Rapamycin enhances apoptosis and increases sensitivity to cisplatin in vitro
    • Shi Y, Frankel A, Radvanyi LG, Penn LZ, Miller RG, Mills GB. Rapamycin enhances apoptosis and increases sensitivity to cisplatin in vitro. Cancer Res 1995;55(9):1982-8.
    • (1995) Cancer Res , vol.55 , Issue.9 , pp. 1982-1988
    • Shi, Y.1    Frankel, A.2    Radvanyi, L.G.3    Penn, L.Z.4    Miller, R.G.5    Mills, G.B.6
  • 44
    • 0034636055 scopus 로고    scopus 로고
    • The immunosuppressive macrolide RAD inhibits growth of human Epstein-Barr virus-transformed B lymphocytes in vitro and in vivo: A potential approach to prevention and treatment of posttransplant lymphoproliferative disorders
    • Majewski M, Korecka M, Kossev P, Li S, Goldman J, Moore J, et al. The immunosuppressive macrolide RAD inhibits growth of human Epstein-Barr virus-transformed B lymphocytes in vitro and in vivo: A potential approach to prevention and treatment of posttransplant lymphoproliferative disorders. Proc Natl Acad Sci USA 2000;97(8):4285-90.
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.8 , pp. 4285-4290
    • Majewski, M.1    Korecka, M.2    Kossev, P.3    Li, S.4    Goldman, J.5    Moore, J.6
  • 45
    • 18344381768 scopus 로고    scopus 로고
    • A novel immunosuppressive drug, FTY220, prevents the cancer progression induced by cyclosporine
    • Tanaka T, Takahara S, Hatori M, Suzuki K, Wang J, Ichimaru N, et al. A novel immunosuppressive drug, FTY220, prevents the cancer progression induced by cyclosporine. Cancer Lett 2002;181(2):165-71.
    • (2002) Cancer Lett , vol.181 , Issue.2 , pp. 165-171
    • Tanaka, T.1    Takahara, S.2    Hatori, M.3    Suzuki, K.4    Wang, J.5    Ichimaru, N.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.