Involvement of the portal at an early step in herpes simplex virus capsid assembly

Journal of Virology

Volumn 79, Issue 16, 2005, Pages 10540-10546

  Newcomb, William W ^a   Homa, Fred L ^b   Brown, Jay C ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS DNA; VIRUS PROTEIN;

ARTICLE; CELL ORGANELLE; CELL STRUCTURE; DNA PACKAGING; HERPES SIMPLEX VIRUS; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; VIRUS ASSEMBLY; VIRUS CAPSID; VIRUS DNA CELL DNA INTERACTION;

BACTERIOPHAGES; CAPSID; CAPSID PROTEINS; HERPESVIRUS 1, HUMAN; VIRAL PROTEINS; VIRUS ASSEMBLY;

MIRIDAE; SIMPLEXVIRUS;

EID: 23244438898     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.79.16.10540-10546.2005     Document Type: Article

References (36)

1. Bazinet, C., and J. King. 1988. Initiation of P22 procapsid assembly in vivo. J. Mol. Biol. 202:77-86.
2. Droge, A., M. A. Santos, A. C. Stiege, J. C. Alonso, R. Lurz, T. A. Trautner, and P. Tavares. 2000. Shape and DNA packaging activity of bacteriophage SPP1 procapsid: protein components and interactions during assembly. J. Mol. Biol. 296:117-132.
3. Guo, P., S. Erickson, W. Xu, N. Olson, T. S. Baker, and D. Anderson. 1991. Regulation of the phage phi 29 prohead shape and size by the portal vertex. Virology 183:366-373.
4. Heymann, J. B., N. Cheng, W. W. Newcomb, B. L. Trus, J. C. Brown, and A. C. Steven. 2003. Dynamics of herpes simplex virus capsid maturation visualized by time-lapse cryo-electron microscopy. Nat. Struct. Biol. 10:334-341.
5. Homa, F. L., and J. C. Brown. 1997. Capsid assembly and DNA packaging in herpes simplex virus. Rev. Med. Virol. 7:107-122.
6. Lamberti, C., and S. K. Weller. 1996. The herpes simplex virus type 1 UL6 protein is essential for cleavage and packaging but not for genomic inversion. Virology 226:403-407.
7. Lee, C. S., and P. Guo. 1995. Sequential interactions of structural proteins in phage phi 29 procapsid assembly. J. Virol. 69:5024-5032.
8. Moore, S. D. and P. E. Prevelige, Jr. 2002. A P22 scaffold protein mutation increases the robustness of head assembly in the presence of excess portal protein. J. Virol. 76:10245-10255.
9. Moore, S. D. and P. E. Prevelige, Jr. 2002. Bacteriophage p22 portal vertex formation in vivo. J. Mol. Biol. 315:975-994.
10. Murialdo, H., and A. Becker. 1978. Head morphogenesis of complex double-stranded deoxyribonucleic acid bacteriophages. Microbiol. Rev. 42:529-576.
11. Newcomb, W. W., and J. C. Brown. 2002. Inhibition of herpes simplex virus replication by WAY-150138: assembly of capsids depleted of the portal and terminase proteins involved in DNA encapsidation. J. Virol. 76:10084-10088.
12. Newcomb, W. W., F. L. Homa, D. R. Thomsen, F. P. Booy, B. L. Trus, A. C. Steven, J. V. Spencer, and J. C. Brown. 1996. Assembly of the herpes simplex virus capsid: characterization of intermediates observed during cell-free capsid assembly. J. Mol. Biol. 263:432-446.
13. Newcomb, W. W., F. L. Homa, D. R. Thomsen, B. L. Trus, N. Cheng, A. C. Steven, F. P. Booy, and J. C. Brown. 1999. Assembly of the herpes simplex virus procapsid from purified components and identification of small complexes containing the major capsid and scaffolding proteins. J. Virol. 73:4239-4250.
14. Newcomb, W. W., F. L. Homa, D. R. Thomsen, Z. Ye, and J. C. Brown. 1994. Cell-free assembly of the herpes simplex virus capsid. J. Virol. 68:6059-6063.
15. Newcomb, W. W., R. M. Juhas, D. R. Thomsen, F. L. Homa, A. D. Burch, S. K. Weller, and J. C. Brown. 2001. The UL6 gene product forms the portal for entry of DNA into the herpes simplex virus capsid. J. Virol. 75:10923-10932.
16. Newcomb, W. W., D. R. Thomsen, F. L. Homa, and J. C. Brown. 2003. Assembly of the herpes simplex virus capsid: identification of soluble scaffold-portal complexes and their role in formation of portal-containing capsids. J. Virol. 77:9862-9871.
17. Newcomb, W. W., B. L. Trus, F. P. Booy, A. C. Steven, J. S. Wall, and J. C. Brown. 1993. Structure of the herpes simplex virus capsid: molecular composition of the pentons and the triplexes. J. Mol. Biol. 232:499-511.
18. Newcomb, W. W., B. L. Trus, N. Cheng, A. C. Steven, A. K. Sheaffer, D. J. Tenney, S. K. Weller, and J. C. Brown. 2000. Isolation of herpes simplex virus procapsids from cells infected with a protease-deficient mutant virus. J. Virol. 74:1663-1673.
19. Patel, A. H., F. J. Rixon, C. Cunningham, and A. J. Davison. 1996. Isolation and characterization of a herpes simplex virus type-1 mutant defective in the UL6 gene. Virology 217:111-123.
20. Poteete, A. R., V. Jarvik, and D. Botstein. 1979. Encapsulation of phage P22 DNA in vitro. Virology 95:550-564.
21. Rixon, F. J. 1993. Structure and assembly of herpesviruses. Semin. Virol. 4:135-144.
22. Rixon, F. J., and D. McNab. 1999. Packaging-competent capsids of a herpes simplex virus temperature-sensitive mutant have properties similar to those of in vitro-assembled procapsids. J. Virol. 73:5714-5721.
23. Roizman, B., and D. M. Knipe. 2001. Herpes simplex viruses and their replication, p. 2399-2459. In D. M. Knipe and P. M. Howley (ed.), Fields virology. Lippincott Williams and Wilkins, Philadelphia, Pa.
24. Sheaffer, A. K., W. W. Newcomb, M. Gao, D. Yu, S. K. Weller, J. C. Brown, and D. J. Tenney. 2001. Herpes simplex virus DNA cleavage and packaging proteins associate with the procapsid prior to its maturation. J. Virol. 75:687-698.
25. Showe, M. K., and L. Onorato. 1978. Kinetic factors and form determination of the head of bacteriophage T4. Proc. Natl. Acad. Sci. USA 75:4165-4169.
26. Singer, G. P., W. W. Newcomb, D. R. Thomsen, F. L. Homa, and J. C. Brown. 2005. Identification of a region in the herpes simplex virus scaffolding protein required for interaction with the portal. J. Virol. 79:132-139.
27. Steven, A. C., and P. G. Spear. 1997. Herpesvirus capsid assembly and envelopment, p. 312-351. In W. Chiu, R. Burnett, and R. L. Garcea (ed.), Structural biology of viruses. Oxford University Press, New York, N.Y.
28. Tatman, J. D., V. G. Preston, P. Nicholson, R. M. Elliott, and F. J. Rixon. 1994. Assembly of herpes simplex virus type 1 capsids using a panel of recombinant baculoviruses. J. Gen. Virol. 75:1101-1113.
29. Taus, N. S., B. Salmon, and J. D. Baines. 1998. The herpes simplex virus 1 UL17 gene is required for localization of capsids and major and minor capsid proteins to intranuclear sites where viral DNA is cleaved and packaged. Virology 252:115-125.
30. Thomsen, D. R., W. W. Newcomb, J. C. Brown, and F. L. Homa. 1995. Assembly of the herpes simplex virus capsid: requirement for the carboxyl-terminal 25 amino acids of the proteins encoded by the UL26 and UL26.5 genes. J. Virol. 69:3690-3703.
31. Thomsen, D. R., L. L. Roof, and F. L. Homa. 1994. Assembly of herpes simplex virus (HSV) intermediate capsids in insect cells infected with recombinant baculoviruses expressing HSV capsid proteins. J. Virol. 68:2442-2457.
32. Trus, B. L., N. Cheng, W. W. Newcomb, F. L. Homa, J. C. Brown, and A. C. Steven. 2004. Structure and polymorphism of the UL6 portal protein of herpes simplex virus type 1. J. Virol. 78:12668-12671.
33. van Driel, R., and E. Couture. 1978. Assembly of the scaffolding core of bacteriophage T4 proheads. J. Mol. Biol. 123:713-719.
34. Ward, P. L., W. O. Ogle, and B. Roizman. 1996. Assemblons: nuclear structures defined by aggregation of immature capsids and some tegument proteins on herpes simplex virus 1. J. Virol. 70:4623-4631.
35. L DNA. Virology 161:198-210.
36. Zhou, Z. H., M. Dougherty, J. Jakana, J. He, F. J. Rixon, and W. Chiu. 2000. Seeing the herpesvirus capsid at 8.5 Å. Science 288:877-880.