The pharmacokinetics of perindoprilat in normal volunteers and patients: Influence of age and disease state

European Journal of Pharmaceutical Sciences

Volumn 26, Issue 1, 2005, Pages 104-113

  Parker, Eva ^a   Aarons, Leon ^a   Rowland, Malcolm ^a   Resplandy, Guillemette ^b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

Author keywords

ACE; Perindopril; Perindoprilat; Plasma protein binding; Population pharmacokinetics

Indexed keywords

CREATININE; DIPEPTIDYL CARBOXYPEPTIDASE; PERINDOPRIL; PERINDOPRILAT;

ADULT; AGED; ARTICLE; BINDING SITE; COMPARTMENT MODEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CREATININE CLEARANCE; DOSE RESPONSE; DRUG CLEARANCE; DRUG DISTRIBUTION; FEMALE; HEART FAILURE; HUMAN; HYPERTENSION; KIDNEY FAILURE; KINETICS; MALE; PRIORITY JOURNAL;

ADMINISTRATION, ORAL; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CLINICAL TRIALS, PHASE I; CLINICAL TRIALS, PHASE II; CREATININE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HEART FAILURE, CONGESTIVE; HUMANS; INDOLES; INJECTIONS, INTRAVENOUS; KIDNEY FAILURE; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; PERINDOPRIL;

EID: 23244438836     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2005.05.006     Document Type: Article

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