Pimozide: The opiate antagonist hypothesis and use in delusions of parasitosis

Dermatology and Psychosomatics

Volumn 5, Issue 4, 2004, Pages 184-186

  Lee, M ^a,c   Koo, J ^b  

^a ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NONE   (United States)

Author keywords

Hypochondriasis; Opioid related disorders; Pimozide; Receptors, opioid; Substance withdrawal syndrome

Indexed keywords

DEXTROPROPOXYPHENE; MORPHINE; NALOXONE; NALTREXONE; OPIATE ANTAGONIST; OPIATE RECEPTOR; PIMOZIDE;

ARTICLE; DELUSION; DELUSION PARASITOSIS; DRUG RECEPTOR BINDING; HUMAN; HYPOTHESIS; MEDICAL LITERATURE; MEDICAL RESEARCH; MEDLINE; NEUROTRANSMISSION; NONHUMAN; OPIATE ADDICTION; PARASITOSIS; PRIORITY JOURNAL; WITHDRAWAL SYNDROME;

EID: 23244435581     PISSN: 14229196     EISSN: None     Source Type: Journal    
DOI: 10.1159/000083097     Document Type: Article

References (27)

1. Ary M, Cox B, Lomax P: Dopaminergic mechanisms in precipitated withdrawal in morphine-dependent rats. J Pharmacol Exp Ther 1977;200:271-276.
2. Bolognia JL, Jorizzo JL, Rapini RP (eds): Dermatology. London, Mosby, 2003.
3. Botschev C, Muller N: Opiate receptor antagonists for delusions of parasitosis. Biol Psychiatry 1991;30:530-531.
4. Charalampous KD, Askew WE: Effect of non-opiate antagonists on stereospecific opiate receptor binding of tritiated naloxone. Res Commun Chem Pathol Pharmacol 1974;8:615-622.
5. Cox B, Ary M, Lomax P: Dopaminergic mechanisms in withdrawal hypothermia in morphine dependent rats. Life Sci 1975;17:41-42.
6. Cox B, Ary M, Lomax P: Dopaminergic involvement in withdrawal hypothermia and thermoregulatory behavior in morphine dependent rats. Pharmacol Biochem Behav 1976;4:259-262.
7. Creese I, Feinberg AP, Snyder SH: Butyrophenone influence on the opiate receptor. Eur J Pharmacol 1976;36:231-235.
8. Driscoll MS, Rothe MJ, Grant-Kels JM, Hale MS: Delusional parasitosis: A dermatologic, psychiatric, and pharmacologic approach. J Am Acad Dermatol 1993;29:1023-1033.
9. el-Kadi AO, Sharif SI: The role of dopamine in the expression of morphine withdrawal. Gen Pharmacol 1998;30:499-505.
10. Fitzpatrick TB, Eisen AZ, Wolff K, Austen KF, Goldsmith LA (eds): Dermatology in General Medicine, ed 4. New York, McGraw-Hill, 1993.
11. Freedberg IM, Eisen AZ, Wolff K, Austen KF, Goldsmith LA (eds): Fitzpatrick's Dermatology in General Medicine, ed 5. New York, McGraw Hill, 1999.
12. Hamann K, Avnstorp C: Delusions of infestation treated with pimozide: A double blind crossover clinical study. Acta Derm Venereol 1982;62:55-58.
13. Hardman JG, Limbird LE, Molinoff PB, Ruddon RW, Gilman AG (eds): Goodman and Gilman's The Pharmacological Basis of Therapeutics, ed 9. New York, McGraw-Hill, 1996.
14. Johnson GC, Anton RF: Pimozide in delusions of parasitosis. J Clin Psychiatry 1983;44:233.
15. Karkalas Y, Lal H: A comparison of haloperidol with methadone in blocking heroin-withdrawal symptoms. A pilot study. Int Pharmacopsychiatry 1973;8:248-251.
16. Manschreck TC: Delusional disorder and shared psychotic disorder; in Sadock BJ, Sadock VA (eds): Kaplan and Sadock's Comprehensive Textbook of Psychiatry, ed 7. Philadelphia, Lippincott Williams and Wilkins, 2000, pp 1243-1263.
17. Munro A: Monosymptomatic hypochondriacal psychosis. Br J Psychiatry Suppl 1988;2:37-40.
18. Lee E, Murase J, Koo J, Lee CS: Psychopharmacology in dermatological practice: A review and update. Dermatol Psychosom 2003;4:131-140.
19. Neisewander JL, Bardo MT: Expression of morphine-conditioned hyperactivity is attenuated by naloxone and pimozide. Psychopharmacology 1987;93:314-319.
20. Opler LA, Feinberg SS: The role of pimozide in clinical psychiatry: A review. J Clin Psychiatry 1991;52:221-233.
21. Pert CB, Snyder SH: Differential interactions of agonists and antagonists with the opiate receptor. Neurosci Res Prog Bull 1975;13:73-79.
22. Rezayat M, Azizi N, Zarrindast MR: On the mechanism(s) of cholecystokinin (CCK): Receptor stimulation attenuates morphine dependence in mice. Pharmacol Toxicol 1997;81:124-129.
23. Sadock BJ, Sadock VA (eds): Kaplan and Sadock's Comprehensive Textbook of Psychiatry, ed 7. Philadelphia, Lippincott Williams and Wilkins, 2000.
24. Sadock BJ, Sadock VA (eds): Kaplan and Sadock's Synopsis of Psychiatry, ed 9. Philadelphia, Lippincott Williams and Wilkins, 2003.
25. Schnur P, Espinoza M, Flores R: Context-specific sensitization to naloxone-precipitated withdrawal in hamsters: Effect of pimozide. Pharmacol Biochem Behav 1994;48:791-797.
26. Shelley WB, Shelley ED: Advanced Dermatologic Therapy II. Philadelphia, PA, WB Saunders, 2001.
27. Tennyson H, Levine N: Neurotropic and psychotropic drugs in dermatology. Dermatol Clin 2001;19:179-197.