Preparation of solid dispersions of nonsteroidal anti-inflammatory drugs with acrylic polymers and studies on mechanisms of drug-polymer interactions

AAPS PharmSciTech

Volumn 3, Issue 2, 2002, Pages

  Pignatello, Rosario ^a   Ferro, Marinella ^a   Puglisi, Giovanni ^a  

^a UNIVERSITY OF CATANIA   (Italy)

Author keywords

Coevaporates; Diflunisal; Eudragit RL100; Eudragit RS100; Flurbiprofen; Piroxicam; Solid dispersions

Indexed keywords

ACRYLIC ACID RESIN; ALCOHOL; AMMONIA; BUFFER; CARBOXYL GROUP; CHLORIDE ION; DIFLUNISAL; EUDRAGIT; EUDRAGIT RS; FLURBIPROFEN; HYDROCHLORIC ACID; LACTOSE; MAGNESIUM STEARATE; MICROCRYSTALLINE CELLULOSE; NONSTEROID ANTIINFLAMMATORY AGENT; PIROXICAM; POLYACRYLIC ACID; QUATERNARY AMMONIUM DERIVATIVE;

ADSORPTION; ARTICLE; ARTIFICIAL ORGAN; BINDING SITE; CHEMICAL INTERACTION; CHEMISTRY; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DIGESTIVE SYSTEM; DRUG ABSORPTION; DRUG ADSORPTION; DRUG DELIVERY SYSTEM; DRUG DISPOSITION; DRUG PURITY; DRUG RELEASE; DRUG SOLUBILITY; DRUG SOLUTION; DRUG STRUCTURE; ELECTRICITY; EMULSION; EVAPORATION; FORECASTING; GASTROENTEROLOGY; GASTROINTESTINAL TRACT; IN VITRO STUDY; INFRARED SPECTROSCOPY; METABOLISM; METHODOLOGY; PH; SOLID STATE; TABLET; X RAY DIFFRACTION; X RAY POWDER DIFFRACTION;

ACRYLIC RESINS; ADSORPTION; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARTIFICIAL ORGANS; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY; DIFLUNISAL; DIGESTIVE SYSTEM; EMULSIONS; FLURBIPROFEN; GASTROENTEROLOGY; METABOLISM; METHODS; PIROXICAM; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TABLETS; X-RAY DIFFRACTION;

EID: 23144461484     PISSN: 15309932     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/pt030210     Document Type: Article

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