Optimization of the pelletization process in a fluid-bed rotor granulator using experimental design

AAPS PharmSciTech

Volumn 1, Issue 4, 2000, Pages

  Korakianiti, Evdokia S ^a   Rekkas, Dimitrios M ^a   Dallas, Paraskevas P ^a   Choulis, Nikolaos H ^a  

^a UNIVERSITY OF ATHENS   (Greece)

Author keywords

Factorial design; Fluid bed rotor granulator; Optimization; Pellets

Indexed keywords

ALPHA LACTOSE; DRUG; MICROCRYSTALLINE CELLULOSE;

ARTICLE; ATMOSPHERIC PRESSURE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG GRANULATION; DRUG PELLET; FLUIDIZED BED; GEOMETRY; PARTICLE SIZE; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; CHEMISTRY; DRUG FORMULATION; DRUG IMPLANT; EQUIPMENT DESIGN; INSTRUMENTATION; METABOLISM; METHODOLOGY; PHARMACEUTICS; REPRODUCIBILITY; STATISTICS;

DRUG COMPOUNDING; DRUG IMPLANTS; EQUIPMENT DESIGN; REPRODUCIBILITY OF RESULTS; RESEARCH DESIGN; TECHNOLOGY, PHARMACEUTICAL;

EID: 23144447487     PISSN: 15309932     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/pt010435     Document Type: Article

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