Examination of aqueous oxidized cellulose dispersions as a potential drug carrier. II. In vitro and in vivo evaluation of phenylpropanolamine release from microparticles and pellets

AAPS PharmSciTech

Volumn 5, Issue 4, 2004, Pages

  Zhu, Lihua ^a   Kumar, Vijay ^b   Banker, Gilbert S ^b  

^a Hospira Inc   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

Aqueous oxidized cellulose dispersions; Oxidized cellulose; Oxidized cellulose phenylpropanolamine ionic complex; Oxycellulose; Phenylpropanolamine hydrochloride

Indexed keywords

OXIDIZED CELLULOSE; PHENYLPROPANOLAMINE; DRUG CARRIER; MICROSPHERE; WATER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; BIODEGRADABILITY; CONTROLLED STUDY; CORRELATION FUNCTION; DISPERSION; DRUG IMPLANTATION; DRUG PELLET; DRUG RELEASE; DRUG SOLUBILITY; FREEZE DRYING; HYDRATION; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; IONIC STRENGTH; MALE; NONHUMAN; PARTICLE SIZE; PH; RAT; SUSTAINED RELEASE PREPARATION; ANIMAL; CHEMISTRY; COMPARATIVE STUDY; DRUG IMPLANT; EVALUATION; METABOLISM; SPRAGUE DAWLEY RAT;

ANIMALS; CELLULOSE, OXIDIZED; DRUG CARRIERS; DRUG IMPLANTS; MALE; MICROSPHERES; PHENYLPROPANOLAMINE; RATS; RATS, SPRAGUE-DAWLEY; WATER;

EID: 23144442453     PISSN: 15309932     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/pt050470     Document Type: Article

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