Protective effect of cerebrospinal fluid containing Danggui Shaoyao San on PC12 cells injured by Aβ25-35

Journal of China Pharmaceutical University

Volumn 36, Issue 4, 2005, Pages 346-349

  Lin, Zhi Hong ^a   Yan, Yong Qing ^a   Zhu, Dan Ni ^a   Yu, Bo Yang ^a   Wang, Qiu Juan ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

amyloid protein; Cerebrospinal fluid; Danggui Shaoyao San; PC12 cells; Protective effect

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ALISMA ORIENTALE EXTRACT; AMYLOID BETA PROTEIN[25-35]; ANGELICA SINENSIS EXTRACT; ATRACTYLODES EXTRACT; ATRACTYLODES MACROCEPHALA EXTRACT; CATALASE; CHINESE DRUG; DANGGUI SHAOYAO SAN; LIGUSTICUM CHUANXIONG EXTRACT; PAEONIA LACTIFLORA EXTRACT; PLANT EXTRACT; PORIA COCOS EXTRACT; UNCLASSIFIED DRUG;

ALISMA; ALISMA ORIENTALE; ANIMAL CELL; AQUEOUS SOLUTION; ARTICLE; ATRACTYLODES; ATRACTYLODES MACROCEPHALA; CELL DAMAGE; CELL PROTECTION; CELL STRAIN; CELL VIABILITY; CEREBROSPINAL FLUID; CONTROLLED STUDY; CYTOTOXICITY; DRUG ISOLATION; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME ASSAY; LIGUSTICUM; LIGUSTICUM CHAUNXIONG EXTRACT; NONHUMAN; RABBIT; RAT;

EID: 23144437921     PISSN: 10005048     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Hardy JA, Higgins GA. Alzheimer's disease: the amyloid cascade hypothesis[J]. Science,1992,256:184-185.
2. Lamber MP, Barlow AK, Chromy BA, et al. Diffusible nonfibrillar ligands derived from Aβ1-42 are potent central nervous system neurotoxins[J]. Proc Nat Acad Sci USA,1998,95:6 448-6 453.
3. Zhou LJ, Zhu XZ. Reactive oxygen species-induced apoptosis in PC12 cells and protective effect of bilobalide[J]. J Pharmacol Exp Ther, 2000,293(3):982-988.
4. Xiao XQ, Wang R, Han YF, et al. Protective effects of huperzine A on beta-amyloid ( 25-35 )-induced oxidative injury in rat pheochromocytoma, cells [J]. Neurosci Lett, 2000, 286(3):155-158.
5. Taylor AW, Streilein JW. Inhibition of antigen-stimulated effector T. cells by human cerebrospinal fluid[J]. Neuroimmunomodulation, 1996,3(2-3):112-118.
6. Nakagawa K, Hirai K, Aoyagi M, et al. Blood cerebrospinal fluid from patients with subarachnoid hemorrhage alter's intracellular calcium regulation in cultured human vascular endothelial cells[J]. Neurol Res,2000,22(6):588-596.
7. (Mei JX), (Zhang BL), (Lu R). Chinese source. (Chin Tradit Herb Drugs),2000,31 (7):523-526.
8. Zhou LJ, Song W, Zhu XZ, et al. Protective effects of bilobalide on amyloid beta-peptide 25-35-induced PC12 cell cytotoxicity[J]. Acta Phamacol Sin,2000, 21(1):75-79.
9. Behl C, Davis JB, Lesley R, et al. Hydrogen peroxide mediates amyloid beta protein toxicity[J]. Cell,1994,817-827.