Effects of prolonged ambient storage of sodium fluoride/heparin specimens on plasma homocysteine [4]

Clinical Chemistry

Volumn 51, Issue 8, 2005, Pages 1564-1565

  Scheidhauer, Ralf ^a,b   Guessregen, Brunhilde ^a   Hohl, Axel ^a   Arndt, Torsten ^a  

^a Bioscientia GmbH   (Germany)

^b Bioscientia Center for Human Genetics   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORIDE SODIUM; HEPARIN; HOMOCYSTEINE;

AMINO ACID BLOOD LEVEL; BLOOD STORAGE; CENTRIFUGATION; FEMALE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; HUMAN TISSUE; LETTER; MALE; MEASUREMENT; NORMAL HUMAN; RISK FACTOR; ROOM TEMPERATURE; STATISTICAL SIGNIFICANCE;

ANTICOAGULANTS; BLOOD SPECIMEN COLLECTION; FALSE POSITIVE REACTIONS; FEMALE; HEPARIN; HOMOCYSTEINE; HUMANS; MALE; REFERENCE VALUES; SODIUM FLUORIDE; TEMPERATURE; TIME FACTORS;

EID: 23044510538     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2005.052852     Document Type: Letter

References (4)

1. Refsum H, Smith AD, Ueland PM, Nexo E, Clarke R, McPartlin J, et al. Facts and recommendations about total homocysteine determinations: an expert opinion. Clin Chem 2004;50:3-32.
2. Arndt T, Guessregen B, Hohl A, Heicke B. Total plasma homocysteine measured by liquid chromatography-tandem mass spectrometry with use of 96-well plates. Clin Chem 2004;50: 755-7.
3. Hughes MP, Carlson TH, McLaughlin MK, Bankson DD. Addition of sodium fluoride to whole blood does not stabilize plasma homocysteine but produces dilution effects on plasma constituents and hematocrit. Clin Chem 1998;44: 2204-6.
4. Clark S, Youngman LD, Sullivan J, Peto R, Collins R. Stabilization of homocysteine in unseparated blood over several days: a solution for epidemiological studies. Clin Chem 2003;49:518-20.