Valuable synthetic building blocks: Useful 2-substituted 5-amino-pyrimidines from a stable precursor

Synthesis

Volumn , Issue 11, 2005, Pages 1817-1821

  Dousson, Cyril B ^a,b   Heron, Nicola M ^a   Hill, George B ^a  

^a ASTRAZENECA   (United Kingdom)

^b Laboratoires IDENIX   (France)

Author keywords

Amidine; Condensation; Heterocycles; Pyrimidines; Vinamidinium

Indexed keywords

POSITIVE IONS; PURIFICATION; SYNTHESIS (CHEMICAL);

AMINOPYRIMIDINE; BUILDING BLOCKS; DIHEXAFLUOROPHOSPHATE; LARGE-SCALE SYNTHEIS;

ORGANIC COMPOUNDS;

2 (DIETHOXYMETHYL)PYRIMIDIN 5 AMINE; 2 [(3 CHLORO 4 FLUOROPHENOXY)METHYL]PYRIMIDIN 5 AMINE; 2 [[(3 FLUOROBENZYL)OXY]METHYL]PYRIMIDIN 5 AMINE; 2 ALKOXY 5 AMINOPYRIMIDINE; AMIDINE; AMINOPYRIMIDINE; BENZYL [(5 AMINOPYRIMIDIN 2 YL)METHYL]CARBAMATE; BENZYL[[5 [[6 METHOXY 7 (3 MORPHOLINO 4 YLPROPOXY)QUINAZOLIN 4 YL]AMINO]YRIMIDIN 2 YL]METHYL]CARBAMATE; N (3 (DIMETHYLAMINO) 2 [[(DIMETHYLAMINO)METHYLENE]AMINO]PROP 2 EN 1 YLIDENE N METHYLMETHANAMINIUM HYDROGEN DIHEXAFLUOROPHOSPHATE; N [3 (DIMETHYLAMINO) 2 [[(DIMETHYLAMINO)METHYLENE]AMINO]PROP 2 EN 1 YLIDENE] N METHYLMETHANAMINIUM HYDROGEN MONOHEXAFLUOROPHOSPHATE; N' [2 (HYDROXYMETHYL)PYRIMIDIN 5 YL] N,N DIMETHYLIMIDOFORMAMIDE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG; VINAMIDINIUM;

ARTICLE; CHEMICAL ANALYSIS; POLYMERIZATION; SUBSTITUTION REACTION; SYNTHESIS;

EID: 23044510450     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-865338     Document Type: Article

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