Downregulation of myelination, energy, and translational genes in Menkes disease brain

Molecular Genetics and Metabolism

Volumn 85, Issue 4, 2005, Pages 291-300

  Liu, Po Ching ^a   Chen, Yi Wen ^b   Centeno, Jose A ^c   Quezado, Martha ^d   Lem, Kristen ^a   Kaler, Stephen G ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^c ARMED FORCES INSTITUTE OF PATHOLOGY   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Brain; Copper; Gene expression; Menkes disease; Myelination; Neurodegeneration

Indexed keywords

ADENOSINE TRIPHOSPHATE; COMPLEMENTARY RNA; COPPER; FLUORESCENT DYE; OLIGONUCLEOTIDE;

ARTICLE; BRAIN; BRAIN CORTEX; BRAIN DEVELOPMENT; BRAIN HYPOXIA; BRAIN LEVEL; CADAVER; CEREBELLUM; CEREBROSPINAL FLUID; CONTROLLED STUDY; COPPER DEFICIENCY; DEMOGRAPHY; DOWN REGULATION; ENERGY METABOLISM; GENE; GENE CONTROL; GENE EXPRESSION; GENE MUTATION; GENE PROBE; GENETIC ANALYSIS; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOTHESIS; INFANT; MALE; MENKES SYNDROME; MYELINATION; NERVE CELL; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY; PRESERVATION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA TRANSLATION; UNINDEXED SEQUENCE; VALIDATION PROCESS;

BRAIN; BRAIN CHEMISTRY; CATION TRANSPORT PROTEINS; COPPER; DNA MUTATIONAL ANALYSIS; DOWN-REGULATION; FATAL OUTCOME; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; INFANT; MALE; MENKES KINKY HAIR SYNDROME; MOLECULAR CHAPERONES; MUTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 23044500932     PISSN: 10967192     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymgme.2005.04.007     Document Type: Article

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