Pharmacokinetic-pharmacodynamic modelling of the cardiovascular effects of drugs - Method development and application to magnesium in sheep

BMC Pharmacology

Volumn 5, Issue , 2005, Pages

  Upton, Richard N ^a   Ludbrook, Guy L ^b  

^a ROYAL ADELAIDE HOSPITAL   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

MAGNESIUM;

ANIMAL EXPERIMENT; ARTERIAL PRESSURE; ARTERY BLOOD FLOW; ARTICLE; BLOOD FLOW VELOCITY; CARDIOVASCULAR EFFECT; CARDIOVASCULAR PARAMETERS; CARDIOVASCULAR SYSTEM; COMPARTMENT MODEL; CONTROLLED STUDY; DATA ANALYSIS; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG PENETRATION; HEART FUNCTION; HEART OUTPUT; HEART RATE; HEART STROKE VOLUME; INTRACELLULAR SPACE; LUNG; METHODOLOGY; NONHUMAN; PREDICTION; PRESSORECEPTOR; PRESSURE VOLUME CURVE; SHEEP; STARLING LAW; SYSTEMIC VASCULAR RESISTANCE; VEIN BLOOD FLOW; VEIN COMPLIANCE; VENOUS PRESSURE; ARTERIAL BLOOD; BLOOD PUMP; DISTRIBUTION VOLUME; PERMEABILITY; PHARMACODYNAMICS; PLOTS AND CURVES; PROCESS DEVELOPMENT; PROCESS MODEL; VALIDATION PROCESS; VASCULAR RESISTANCE; VENOUS BLOOD; ANIMAL; BIOLOGICAL MODEL; DRUG EFFECT; HEMODYNAMICS; TISSUE DISTRIBUTION;

ANIMALS; CARDIOVASCULAR SYSTEM; HEMODYNAMICS; MAGNESIUM; MODELS, CARDIOVASCULAR; SHEEP; TISSUE DISTRIBUTION;

EID: 23044492936     PISSN: 14712210     EISSN: 14712210     Source Type: Journal    
DOI: 10.1186/1471-2210-5-5     Document Type: Article

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