XAGE-1 expression in non-small cell lung cancer and antibody response in patients

Clinical Cancer Research

Volumn 11, Issue 15, 2005, Pages 5496-5503

  Nakagawa, Kazuhiko ^a   Noguchi, Yuji ^a   Uenaka, Akiko ^a   Sato, Shuichiro ^a   Okumura, Hideo ^a   Tanaka, Motoyuki ^a   Shimono, Michihide ^a   Eldib, Ali Mohamed Ali ^a   Ono, Toshiro ^a   Ohara, Nobuya ^a   Yoshino, Tadashi ^a   Yamashita, Kazuki ^b   Tsunoda, Tsukasa ^b   Aoe, Motoi ^a   Shimizu, Nobuyoshi ^a   Nakayama, Eiichi ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b KAWASAKI MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; MESSENGER RNA; MONOCLONAL ANTIBODY; TUMOR ANTIGEN; UNCLASSIFIED DRUG; XAGE 1 ANTIBODY; XAGE 1 ANTIGEN; XAGE 1A ANTIGEN; XAGE 1B ANTIGEN; XAGE 1C ANTIGEN; XAGE 1D ANTIGEN;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ANTIGEN RECOGNITION; ARTICLE; CANCER CLASSIFICATION; CANCER IMMUNOTHERAPY; CONTROLLED STUDY; DRUG TARGETING; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; HUMORAL IMMUNITY; IMMUNOHISTOCHEMISTRY; LUNG ADENOCARCINOMA; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; XAGE 1 GENE;

ADENOCARCINOMA; ANTIBODIES, MONOCLONAL; ANTIGENS, NEOPLASM; BLOTTING, WESTERN; CARCINOMA, NON-SMALL-CELL LUNG; DATABASES; DNA PRIMERS; DNA, COMPLEMENTARY; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXPRESSED SEQUENCE TAGS; GENETIC VECTORS; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOTHERAPY; LUNG NEOPLASMS; PLASMIDS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TREATMENT OUTCOME;

EID: 23044462228     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-05-0216     Document Type: Article

References (14)

1. Boon T, Old LJ. Tumor antigens. Curr Opin Immunol 1997;9:681-3.
2. Scanlan MJ, Gure AO, Jungbluth AA, et al. Cancer/testis antigens: an expanding family of targets for cancer immunotherapy. Immunol Rev 2002;188:22-32.
3. Scanlan MJ, Simpson AJG, Old LJ. The cancer/testis genes: review, standardization, and commentary. Cancer Immun 2004;4:1.
4. Jäger E, Chen YT, Drijfhout JW, et al. Simultaneous humoral and cellular immune response against cancer-testis antigen NY-ESO-1: definition of human histocompatibility leukocyte antigen (HLA) -A2-binding peptide epitopes. J Exp Med 1998;187:265-70.
5. Ayyoub M, Stevanovic S, Sahin U, et al. Proteasome-assisted identification of a SSX-2-derived epitope recognized by tumor-reactive CTL infiltrating metastatic melanoma. J Immunol 2002;168:1717-22.
6. Brinkmann U, Vasmatzis G, Lee B, Pastan I. Novel genes in the PAGE and GAGE family of tumor antigens found by homology walking in the dbEST database. Cancer Res 1999;59:1445-8.
7. Liu XF, Helman LJ, Yeung C, Bera TK, Lee B, Pastan I. XAGE-1, a new gene that is frequently expressed in Ewing's sarcoma. Cancer Res 2000;60:4752-5.
8. Zendman AJ, van Kraats AA, den Hollander AI, Weidle UH, Ruiter DJ, van Muijen GN. Characterization of XAGE-1b, a short major transcript of cancer/testis-associated gene XAGE-1, induced in melanoma metastasis. Int J Cancer 2002;97:195-204.
9. Zendman AJ, Van Kraats AA, Weidle UH, Ruiter DJ, Van Muijen GN. The XAGE family of cancer/testis-associated genes: alignment and expression profile in normal tissues, melanoma lesions and Ewing's sarcoma. Int J Cancer 2002;99:361-9.
10. Egland KA, Kumar V, Duray P, Pastan I. Characterization of overlapping XAGE-1 transcripts encoding a cancer testis antigen expressed in lung, breast, and other types of cancers. Mol Cancer Ther 2002;1:441-50.
11. Ali Eldib AM, Ono T, Shimono M, et al. Immunoscreening of a cDNA library from a lung cancer cell line using autologous patient serum: identification of XAGE-1b as a dominant antigen and its immunogenicity in lung adenocarcinoma. Int J Cancer 2004;108:558-63.
12. Kurashige T, Noguchi Y, Saika T, et al. NY-ESO-1 expression and immunogenicity associated with transitional cell carcinoma; correlation with tumor grade. Cancer Res 2001;61:4671-4.
13. Bobbins J, Dilworth SM, Laskey RA, Dingwall C. Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequence. Cell 1991;64:615-23.
14. Stocken E, Jäger E, Chen YT, et al. A survey of the humoral immune response of cancer patients to a panel of human tumor antigens. J Exp Med 1998;187:1349-54.