Real-time PCR screening for 16S rRNA mutations associated with resistance to tetracycline in Helicobacter pylori

Antimicrobial Agents and Chemotherapy

Volumn 49, Issue 8, 2005, Pages 3166-3170

  Glocker, Erik ^a   Berning, Marco ^a   Gerrits, Monique M ^b   Kusters, Johannes G ^b   Kist, Manfred ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BISMUTH SALT; CLARITHROMYCIN; DNA; METRONIDAZOLE; RNA 16S; TETRACYCLINE;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIUM CULTURE; CONTROLLED STUDY; DNA EXTRACTION; DRUG EFFICACY; GENE MUTATION; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; HUMAN TISSUE; MUTATIONAL ANALYSIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RNA GENE; STOMACH BIOPSY;

DNA, BACTERIAL; DNA, RIBOSOMAL; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; MUTATION; POLYMERASE CHAIN REACTION; RNA, RIBOSOMAL, 16S; SENSITIVITY AND SPECIFICITY; TETRACYCLINE; TETRACYCLINE RESISTANCE;

EID: 23044458441     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.49.8.3166-3170.2005     Document Type: Article

References (22)

1. Cammarota, G., A. Martino, G. Pirozzi, R. Cianci, G. Branca, E. C. Nista, A. Cazzato, O. Cannizzaro, L. Miele, A. Grieco, A. Gasbarrini, and G. Gasbarrini. 2004. High efficacy of 1-week doxycycline- and amoxicillin-based quadruple regimen in a culture-guided, third-line treatment approach for Helicobacter pylori infection. Aliment. Pharmacol. Ther. 19:789-795.
2. Chi, C. H., C. Y. Lin, B. S. Sheu, H. B. Yang, A. H. Huang, and J. J. Wu. 2003. Quadruple therapy containing amoxicillin and tetracycline is an effective regimen to rescue failed triple therapy by overcoming the antimicrobial resistance of Helicobacter pylori. Aliment. Pharmacol. Ther. 18:347-353.
3. Dailidiene, D., M. T. Bertoli, J. Miciuleviciene, A. K. Mukhopadhyay, G. Dailide, M. A. Pascasio, L. Kupcinskas, and D. E. Berg. 2002. Emergence of tetracycline resistance in Helicobacter pylori: multiple mutational changes in 16S ribosomal DNA and other genetic loci. Antimicrob. Agents Chemother. 46:3940-3946.
4. Gerrits, M. M., M. R. De Zoete, N. L. Arents, E. J. Kuipers, and J. G. Kusters. 2002. 16S rRNA mutation-mediated tetracycline resistance in Helicobacter pylori. Antimicrob. Agents Chemother. 46:2996-3000.
5. Gerrits, M. M., M. Berning, A. H. M. Van Vliet, E. J. Kuipers, and J. G. Kusters. 2003. Effects of 16S rRNA gene mutations on tetracycline resistance in Helicobader pylori. Antimicrob. Agents Chemother. 47:2984-2986.
6. Gisbert, J. P., and J. M. Pajares. 2001. Helicobacter pylori therapy: first-line options and rescue regimen. Dig. Dis. 19:134-143.
7. Glocker, E., and M. Kist. 2004. Rapid detection of point mutations in the gyrA gene of Helicobacter pylori conferring resistance to ciprofloxacin by a fluorescence resonance energy transfer-based real-time PCR approach. J. Clin. Microbiol. 42:2241-2246.
8. Glupczynski, Y., F. Mégraud, M. Lopez-Brea, and L. P. Andersen. 2001. European multicentre survey of in vitro antimicrobial resistance in Helicobacter pylori. Eur. J. Clin. Microbiol. Infect. Dis. 20:820-823.
9. He, Q., J. P. Wang, M. Osato, and L. B. Lachman. 2002. Real-time quantitative PCR for detection of Helicobacter pylori. J. Clin. Microbiol. 40:3720-3728.
10. Heep, M., M. Kist, S. Strobel, D. Beck, and N. Lehn. 2000. Secondary resistance among 554 isolates of Helicobacter pylori after failure of therapy. Eur. J. Clin. Microbiol. Infect. Dis. 19:538-541.
11. Kist, M. 1991. Diagnostische Verfahrensrichtlinien der DGHM: Isolierung und Identifizierung von Bakterien der Gattungen Campylobacter und Helicobacter. Zentbl. Bakteriol. Parasitenkd. Infektkrankh. Hyg. Abt. I Orig. 276:124-139.
12. Kist, M., and E. Glocker. 2004. ResiNet-a nationwide German sentinel study for surveillance and analysis of antimicrobial resistance in Helicobacter pylori. Euro. Surveill. Q. 1:44-46
13. Leung, W. K., and J. J. Sung. 2002. Review article: intestinal metaplasia and gastric carcinogenesis. Aliment. Pharmacol. Ther. 16:209-216.
14. Malfertheiner, P., F. Mégraud, C. O'Morain, A. P. S. Hungin, R. Jones, A. Axon, D. Y. Graham, G. Tytgat, and The European Helicobacter pylori Study Group (EHPSG). 2002. Current concepts in the management of Helicobacter pylori infection. The Maastricht Consensus Report. Aliment. Pharmacol. Ther. 16:167-189.
15. Matsumura, M., Y. Hikiba, K. Ogura, G. Togo, I. Tsukuda, K. Ushikawa, Y. Shiratori, and M. Omata. 2001. Rapid detection of mutations in the 23S rRNA gene of Helicobacter pylori that confers resistance to clarithromycin treatment to the bacterium. J. Clin. Microbiol. 39:691-695.
16. Oleastro, M., A. Ménard, A. Santos, H. Lamouliatte, L. Monteiro, P. Barthélémy, and F. Mégraud. 2003. Real-time PCR assay for rapid and accurate detection of point-mutations conferring resistance to clarithromycin in Helicobacter pylori. J. Clin. Microbiol. 41:397-402.
17. Ribeiro, M. L., M. M. Gerrits, Y. H. Benvengo, M. Berning, A. P. Godoy, E. J. Kuipers, S. Mendonca, S., A. H. van Vliet, J. Pedrazzoli, Jr., and J. G. Kusters. 2003. Detection of high-level tetracycline resistance in clinical isolates of Helicobacter pylori using PCR-RFLP. FEMS Immunol. Med. Microbiol. 40:57-61.
18. Stolte, M., E. Bayerdorffer, A. Morgner, B. Alpen, T. Wundisch, C. Thiede, and A. Neubauer. 2002. Helicobacter and gastric MALT lymphoma. Gut 50(Suppl. 3):19-24.
19. Strobel, S., S. Bereswill, P. Balig, P. Allgaier, H.-G. Sonntag, and M. Kist. 1998. Identification and analysis of a new vacA genotype variant of Helicobacter pylori in different patient groups in Germany. J. Clin. Microbiol. 36:1285-1290.
20. Suerbaum, S., and P. Michetti. 2002. Helicobacter pylori infection. N. Engl. J. Med. 347:1175-1186.
21. Tomb, J. F., O. White, A. R. Kerlavage, R. A. Clayton, G. G. Sutton, R. D. Fleischmann, K. A. Ketchum, H. P. Klenk, S. Gill, B. A. Dougherty, K. Nelson, J. Quackenbush, L. Zhou, E. F. Kirkness, S. Peterson, B. Loftus, D. Richardson, R. Dodson, H. G. Khalak, A. Glodek, K. McKenney, L. M. Fitzegerald, N. Lee, M. D. Adams, J. C. Venter, et al. 1997. The complete genome sequence of the gastric pathogen Helicobacter pylori. Nature 388: 539-547.
22. Trieber, C. A., and D. E. Taylor. 2002. Mutations in the 16S rRNA genes of Helicobacter pylori mediate resistance to tetracycline. J. Bacteriol. 184:2131-2140.