Dihydrotachysterol therapy for hypoparathyroidism: Consequences of inadequate monitoring. Five cases and a review

Experimental and Clinical Endocrinology and Diabetes

Volumn 113, Issue 7, 2005, Pages 376-380

  Quack, I ^a   Zwernemann, C ^a   Weiner, S M ^a   Sellin, L ^a   Henning, B F ^a   Waldherr, R ^a   Buchner N J ^a   Stegbauer, J ^a   Vonend, O ^a   Rump, Lars Christian ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Dihydrotachysterol; Hypercalcaemia; Hypoparathyroidism; Kidney failure; Parathyroid hormone; Vitamin D

Indexed keywords

BISPHOSPHONIC ACID DERIVATIVE; CALCIUM; CREATININE; DIHYDROTACHYSTEROL; FUROSEMIDE; LOOP DIURETIC AGENT; PARATHYROID HORMONE; SHORT ACTING DRUG; SODIUM CHLORIDE; VITAMIN D DERIVATIVE;

AGED; ANAMNESIS; ARTICLE; CALCIUM METABOLISM; CLINICAL ARTICLE; CLINICAL PRACTICE; FEMALE; HUMAN; HYPERCALCEMIA; HYPOPARATHYROIDISM; INCIDENCE; INTENSIVE CARE UNIT; KIDNEY BIOPSY; KIDNEY FAILURE; KIDNEY FUNCTION; MALE; PARATHYROID GLAND; PATIENT MONITORING; PRIMARY MEDICAL CARE; PRIORITY JOURNAL;

AGED; DIHYDROTACHYSTEROL; DRUG MONITORING; FEMALE; HUMANS; HYPERCALCEMIA; HYPOPARATHYROIDISM; KIDNEY FAILURE; MALE; VITAMIN D;

EID: 23044453234     PISSN: 09477349     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-865724     Document Type: Article

References (17)

1. Blind E, Fassnacht M, Korber C, Korber-Hafner N, Reiners C, Allolio B. Severe vitamin D(dihydrotachysterol)-intoxication with temporary anemia and hypercalcemia responsive to bisphosphonates. Dtsch Med Wochenschr 2001; 126: T21-T24
2. Bushinsky DA, Monk RD. Electrolyte quintet: Calcium. Lancet 1998; 352: 306-311
3. Jehle DR, Keller F, Schwarz A, Jehle PM. Hypercalcemia-induced renal insufficiency during therapy with dihydrotachysterol. J Med 1999; 30: 39-50
4. Lamberg BA, Tikkanen MJ. Hypercalcaemia due to dihydrotachysterol treatment in patients with hypothyroidism after thyroidectomy. Br Med J (Clin Res Ed) 1981; 283: 461-462
5. Lee KW, Cohen KL, Walters JB, Federman DG. Iatrogenic vitamin D intoxication: report of a case and review of vitamin D physiology. Conn Med 1999; 63: 399-403
6. Mason RS, Lissner D, Grunstein HS, Posen S. A simplified assay for dihydroxylated vitamin D metabolites in human serum: application to hyper- and hypovitaminosis D. Clin Chem 1980; 26: 444-450
7. McIntyre CW, Schroeder NJ, Burrin JM, Cunningham J. Effects of new analogues of vitamin D on bone cells: implications for treatment of uremic bone disease. Kidney Int 1999; 55: 500-511
8. Pattou F, Combemale F, Fabre S, Carnaille B, Decoulx M, Wemeau JL, Racadot A, Proye C. Hypocalcemia following thyroid surgery: incidence and prediction of outcome. World J Surg 1998; 22: 718-724
9. Pettifor JM, Bikle DD, Cavaleros M, Zachen D, Kamdar MC, Ross FP. Serum levels of free 1,25-dihydroxyvitamin D in vitamin D toxicity. Ann Intern Med 1995; 122: 511-513
10. Puig J, Corcoy R, Rodriguez-Espinosa J. Anemia secondary to vitamin D intoxication. Ann Intern Med 1998; 128: 602-603
11. Schilling T, Ziegler R. Current therapy of hypoparathyroidism - a survey of German endocrinology centers. Exp Clin Endocrinol Diabetes 1997; 105: 237-241
12. Slatopolsky E, Finch J, Brown A. New vitamin D analogs. Kidney Int 2003; 85 (Suppl): 83-87
13. Steddon SJ, Schroeder NJ, Cunningham J. Vitamin D analogues: how do they differ and what is their clinical role? Nephrol Dial Transplant 2001; 16: 1965-1967
14. Suda T, Hallick RB, DeLuca HF, Schnoes HK. 25-hydroxydihydrotachysterol. Synthesis and biological activity. Biochemistry 1970; 9: 1651-1657
15. Vieth R. Vitamin D supplementation, 25-hydroxyvitamin D concentrations, and safety. Am J Clin Nutr 1999; 69: 842-856
16. Winer KK, Yanovski JA, Cutler GB Jr. Synthetic human parathyroid hormone 1-34 vs calcitriol and calcium in the treatment of hypoparathyroidism. Jama 1996; 276: 631-636
17. Winer KK, Ko CW, Reynolds JC, Dowdy K, Keil M, Peterson D, Gerber LH, McGarvey C, Cutler GB Jr. Long-term treatment of hypoparathyroidism: a randomized controlled study comparing parathyroid hormone-(1-34) versus calcitriol and calcium. J Clin Endocrinol Metab 2003; 88: 4214-4220