Recent developments in the genetics of alcohol-related phenotypes

Alcoholism: Clinical and Experimental Research

Volumn 29, Issue 7, 2005, Pages 1321-1324

  Hesselbrock, Victor ^a   Higuchi, Susumu ^b   Soyka, Michael ^c  

^a UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

^b KURIHAMA NATIONAL HOSPITAL   (Japan)

^c LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

ADH ALDH; Conduct disorder; Externalizing behavior; Genetics; Phenotypes; Susceptibility

Indexed keywords

ALDEHYDE DEHYDROGENASE ISOENZYME 2; SEROTONIN;

AGGRESSION; ALCOHOL CONSUMPTION; ALCOHOL METABOLISM; ALCOHOLISM; AMNESIA; CHROMOSOME 2; CONDUCT DISORDER; CONFERENCE PAPER; CONTINUING EDUCATION; DNA POLYMORPHISM; GENETIC LINKAGE; GENETIC SCREENING; GENETICS; GERMANY; HUMAN; NEUROTRANSMITTER RELEASE; PHENOTYPE; POLYNEUROPATHY; PRIORITY JOURNAL; PSYCHOPATHY; QUANTITATIVE GENETICS; SUICIDAL BEHAVIOR;

ALCOHOLISM; ALLELES; ANTISOCIAL PERSONALITY DISORDER; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 2; CONDUCT DISORDER; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INTERNAL-EXTERNAL CONTROL; PHENOTYPE;

EID: 23044451773     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ALC.0000171955.52431.E7     Document Type: Conference Paper

References (13)

1. Bucholz K, Cadoret R, Cloninger CR, Dinwiddie S, Hesselbrock V, Nurnberger J, Reich T, Schmidt I, Schuckit M (1994) A new, semistructured psychiatric interview for use in genetic linkage studies: aA report of the reliability of the SSAGA. J Studies Alc 55:149-158.
2. Dick DM, Li T-K, Edenberg HJ, Hesselbrock VM, Kramer JK, Kuperman S, Porjesz B, Nurnberger JI, Bucholz KK, Foroud T (2004) A genome-wide screen for genes influencing conduct disorder. Mol Psych 9:81-86.
3. Gorwood P, Aissi F, Batel P, Ades J, Cohen-Salmon C, Harmon M, Boni C, Lanfurmey L (2002) Reappraisal of the serotonin 5 HT (1B) receptor gene in alcoholism: of mice and men. Brain Res Bull 57:103-107.
4. Hesselbrock V, Dick D, Hesselbrock M, Foroud T, Schuckit M, Bucholz KK, Edenberg H, Nurnberger J (2004) Suggestive linkage for phenotypes of suicide attempts and suicidality in the COGA sample. Alcohol Clin Exp Res 28(Suppl 5):70-76.
5. Hesselbrock M, Easton C, Bucholz KK, Schuckit M, Hesselbrock V (1999) A validity study of the SSAGA: a comparison with the SCAN. Addiction 94:1361-1370.
6. Kranzler HR, Hernandez-Avila CA, Gelernter J (2002) Polymorphism of the 5 HT 1B receptor gene (HTR1B): strong within-locus linkage disequilibrium without association to antisocial substance dependence. Neuropsychopharm 26:115-122.
7. Lappalainen J, Long JC, Eggert M, Ozaki N, Robin RW, Brown GL, Naukkarinen H, Virkunnen M, Linnoila M, Goldman D (1998) Linkage of antisocial alcoholism to serotonin 5-HT 1B receptor gene in 2 populations. Arch Gen Psychiatry 55:989-994.
8. Masaki T, Mochizuki H, Matsushita S, Yokoyama A, Kamakura K, Higuchi S (2004) Association of aldehyde dehydrogenase-2 polymorphisms with alcoholic polyneuropathy in humans. Neurosci Lett 363:288-290.
9. Matsushita S, Kato M, Muramatsu T, Higuchi S (2000) Alcohol and aldehyde dehydrogenase genotypes in Korsakoff syndrome. Alcohol Clin Exp Res 24:337-340.
10. Mochizuki H, Masaki T, Yokoyama A, Matsushita S, Kamakura K, Motoyoshi K, Higuchi S (2004) Prolonged central sensory conduction time in alcoholics with hypoactive aldehyde dehydrogenase-2. Neurosci Res 50:233-236.
11. O'Connor S, Morzorati S, Christian J, Li T-K (1998) Clamping breath alcohol concentration reduces experimental variance: application to the study of acute tolerance to alcohol and alcohol elimination rate. Alcohol Clin Exp Res 22:202-210.
12. Yokoyama A, Muramatsu T, Ohmori T, Yokoyama T, Matsushita S, Higuchi S, Maruyama K, Ishii H (2001) Alcohol and aldehyde dehydrogenase gene polymorphisms and oropharyngolaryngeal, esophageal, and stomach cancers in Japanese alcoholics. Carcinogenesis 22:433-439.
13. Yokoyama A, Yokoyama T, Muramatsu T, Omori T, Matsushita S, Higuchi S, Maruyama K, Ishii H (2003) Macrocytosis, a new predictor of esophageal squamous cell carcinoma in Japanese alcoholic men. Carcinogenesis 24:1773-1778.