Development and validation of a whole-cell inhibition assay for bacterial methionine aminopeptidase by surface-enhanced laser desorption ionization-time of flight mass spectrometry

Antimicrobial Agents and Chemotherapy

Volumn 49, Issue 8, 2005, Pages 3428-3434

  Greis, Kenneth D ^a   Zhou, Songtao ^a   Siehnel, Richard ^a   Klanke, Chuck ^a,b   Curnow, Alan ^a   Howard, Jeremy ^a   Layh Schmitt, Gerlinde ^a,b  

^a PROCTER AND GAMBLE PHARMACEUTICALS   (United States)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARABINOSE; BACTERIAL PROTEIN; BIOLOGICAL MARKER; FORMYLMETHIONINE; GENE PRODUCT; METHIONINE; METHIONYL AMINOPEPTIDASE; PEPTIDE DEFORMYLASE; PROTEINASE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL CELL; BACTERIAL GROWTH; BACTERIAL STRAIN; CONTROLLED STUDY; DRUG SCREENING; DRUG TARGETING; ENZYME ASSAY; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN SYNTHESIS; SURFACE ENHANCED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; VALIDATION PROCESS; WHOLE CELL; WHOLE CELL INHIBITION ASSAY;

AMINOPEPTIDASES; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BIOLOGICAL MARKERS; DOWN-REGULATION; ENZYME INHIBITORS; ESCHERICHIA COLI; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 23044443508     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.49.8.3428-3434.2005     Document Type: Article

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