Factor XIa dimer in the activation of factor IX

Biochemistry

Volumn 44, Issue 30, 2005, Pages 10416-10422

  Sinha, Dipali ^a   Marcinkiewicz, Mariola ^a   Lear, James D ^b   Walsh, Peter N ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOASSAY; CENTRIFUGATION; CHEMICAL BONDS; COAGULATION; DIMERS; GEL PERMEATION CHROMATOGRAPHY; MONOMERS;

GEL FILTRATION CHROMATOGRAPHY; HOMODIMERS; ULTRACENTRIFUGATION;

PROTEINS;

BLOOD CLOTTING FACTOR 11A; BLOOD CLOTTING FACTOR 9; DIMER; PREKALLIKREIN; PROTEIN SUBUNIT;

AMINO ACID SEQUENCE; ARTICLE; DISULFIDE BOND; GEL FILTRATION CHROMATOGRAPHY; HUMAN; HUMAN CELL; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; THROMBOCYTE ACTIVATION; ULTRACENTRIFUGATION;

AMINO ACID SUBSTITUTION; CELL LINE; CYSTEINE; DEXTRAN SULFATE; DIMERIZATION; FACTOR IX; FACTOR XIA; FACTOR XIIA; GLYCINE; HUMANS; HYDROLYSIS; OLIGOPEPTIDES; PARTIAL THROMBOPLASTIN TIME; PLATELET ACTIVATION; PYRROLIDONECARBOXYLIC ACID; SUBSTRATE SPECIFICITY; THROMBIN;

EID: 23044442096     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi050361x     Document Type: Article

References (26)

1. Gailani, D., and Broze, G. J., Jr. (1991) Factor XI activation in a revised model of blood coagulation, Science 253, 909-912.
2. Naito, K., and Fujikawa, K. (1991) Activation of human blood coagulation factor XI independent of factor XII. Factor XI is activated by thrombin and factor XIa in the presence of negatively charged surfaces, J. Biol. Chem. 266, 7353-7358.
3. Saito, H., and Goldsmith, G. H., Jr. (1977) Plasma thromboplastin antecedent (PTA, factor XI): A specific and sensitive radioimmunoassay, Blood 50, 377-385.
4. McMullen, B. A., Fujikawa, K., and Davie, E. W. (1991) Location of the disulfide bonds in human coagulation factor XI: The presence of tandem apple domains, Biochemistry 30, 2056-2060.
5. Chung, D. W., Fujikawa, K., McMullen, B. A., and Davie, E. W. (1986) Human plasma prekallikrein, a zymogen to a serine protease that contains four tandem repeats, Biochemistry 25, 2410-2417.
6. McMullen, B. A., Fujikawa, K., and Davie, E. W. (1991) Location of the disulfide bonds in human plasma prekallikrein: The presence of four novel apple domains in the amino-terminal portion of the molecule, Biochemistry 30, 2050-2056.
7. Fujikawa, K., Chung, D. W., Hendrickson, L. E., and Davie, E. W. (1986) Amino acid sequence of human factor XI, a blood coagulation factor with four tandem repeats that are highly homologous with plasma prekallikrein, Biochemistry 25, 2417-2424.
8. Meijers, J. C., Davie, E. W., and Chung, D. W. (1992) Expression of human blood coagulation factor XI: Characterization of the defect in factor XI type III deficiency, Blood 79, 1435-1440.
9. Gailani, D., Ho, D., Sun, M. F., Cheng, Q., and Walsh, P. N. (2001) Model for a factor IX activation complex on blood platelets: Dimeric conformation of factor XIa is essential, Blood 97, 3117-3122.
10. Sinha, D., Koshy, A., Seaman, F. S., and Walsh, P. N. (1985) Functional characterization of human blood coagulation factor XIa using hybridoma antibodies, J. Biol. Chem. 260, 10714-10719.
11. Singh, R., Blattler, W. A., and Collinson, A. R. (1995) Assay for thiols based on reactivation of papain, Methods Enzymol. 251, 229-237.
12. Sinha, D., Marcinkiewicz, M., Gailani, D., and Walsh, P. N. (2002) Molecular cloning and biochemical characterization of rabbit factor XI, Biochem. J. 367, 49-56.
13. Gailani, D., Sun, M. F., and Sun, Y. (1997) A comparison of murine and human factor XI, Blood 90, 1055-1064.
14. Bock, P. E., and Shore, J. D. (1983) Protein-protein interactions in contact activation of blood coagulation. Characterization of fluorescein-labeled human high molecular weight kininogen-light chain as a probe, J. Biol. Chem. 258, 15079-15086.
15. Laue, T., Shaw, B. D., Ridgeway, T. M., and Pelletier, S. L. (1992) in Analytical Ultracentrifiigation in Biochemistry and Polymer Science (Harding, S. E., Rowe, A. J., and Horton, J. C., Eds.) pp 90-125, The Royal Society of Chemistry, Cambridge, U.K.
16. Fairman, R., Fenderson, W., Hail, M. E., Wu, Y., and Shaw, S. Y. (1999) Molecular weights of CTLA-4 and CD80 by sedimentation equilibrium ultracentrifugation, Anal. Biochem. 270, 286-295.
17. Minton, A. P. (1990) Quantitative characterization of reversible molecular associations via analytical centrifugation, Anal. Biochem. 190, 1-6.
18. Gailani, D., and Broze, G. J. (2001) in Metabolic and Molecular Basis of Inherited Disease (Scriver, C. R., Beaudet, A. L., Sly, W. S., Valle, D., Childs, B., Kinzler, K., and Vogelstein, B., Eds.) pp 4433-4453, McGraw-Hill, New York.
19. Pugh, R. E., McVey, J. H., Tuddenham, E. G., and Hancock, J. F. (1995) Six point mutations that cause factor XI deficiency, Blood 85, 1509-1516.
20. Mitchell, M., Cutler, J., Thompson, S., Moore, G., Jenkins Ap Rees, E., Smith, M., Savidge, G., and Alhaq, A. (1999) Heterozygous factor XI deficiency associated with three novel mutations, Br. J. Haematol. 107, 763-765.
21. Meijers, J. C., Mulvihill, E. R., Davie, E. W., and Chung, D. W. (1992) Apple four in human blood coagulation factor XI mediates dimer formation, Biochemistry 31, 4680-4684.
22. Imanaka, Y., Lal, K., Nishimura, T., Bolton-Maggs, P. H., Tuddenham, E. G., and McVey, J. H. (1995) Identification of two novel mutations in non-Jewish factor XI deficiency, Br J. Haematol. 90, 916-920.
23. Ragni, M. V., Sinha, D., Seaman, F., Lewis, J. H., Spero, J. A., and Walsh, P. N. (1985) Comparison of bleeding tendency, factor XI coagulant activity, and factor XI antigen in 25 factor XI-deficient kindreds, Blood 65, 719-724.
24. Saito, H., Ratnoff, O. D., Bouma, B. N., and Seligsohn, U. (1985) Failure to detect variant (CRM+) plasma thromboplastin antecedent (factor XI) molecules in hereditary plasma thromboplastin antecedent deficiency: A study of 125 patients of several ethnic backgrounds, J. Lab. Clin. Med. 106, 718-722.
25. Sun, Y., and Gailani, D. (1996) Identification of a factor IX binding site on the third apple domain of activated factor XI, J. Biol. Chem. 271, 29023-29028.
26. Baglia, F. A., Jameson, B. A., and Walsh, P. N. (1995) Identification and characterization of a binding site for platelets in the Apple 3 domain of coagulation factor XI, J. Biol. Chem. 270, 6734-6740.