Allosterically activated Diels-Alder catalysis by a ribozyme

Journal of the American Chemical Society

Volumn 127, Issue 30, 2005, Pages 10492-10493

  Helm, Mark ^a   Petermeier, Markus ^a   Ge, Bixia ^a   Fiammengo, Roberto ^a   Jäschke, Andres ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

RIBOZYME;

ALLOSTERISM; ARTICLE; DIELS ALDER REACTION; DNA TEMPLATE; DNA TRANSCRIPTION; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PROTEIN DOMAIN; REACTION TIME; RNA ISOLATION; ULTRAVIOLET SPECTROSCOPY;

ANTHRACENES; BASE SEQUENCE; BIOTIN; CATALYSIS; DNA-DIRECTED RNA POLYMERASES; KINETICS; MALEIMIDES; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; NUCLEOTIDES; RNA; RNA, CATALYTIC; THEOPHYLLINE; VIRAL PROTEINS;

EID: 23044436253     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja052886i     Document Type: Article

References (18)

1. Soukup, G. A.; Breaker, R. R. Proc. Natl. Acad Sci. U.S.A. 1999, 96 3584-3589.
2. Robertson, M. P.; Ellington, A. D. Nat. Biotechnol. 1999, 17, 62-66.
3. Najafi-Shoushtari, S. H.; Mayer, G.; Famulok, M. Nucleic Acids Res. 2004, 32, 3212-3219.
4. Kuwabara, T.; Warashina, M.; Tanabe, T.; Tani, K.; Asano, S.; Taira, K. Mol. Cell 1998, 2, 617-627.
5. Winkler, W. C.; Nahvi, A.; Roth, A.; Collins, J. A.; Breaker, R. R. Nature 2004, 428, 281-286.
6. Seelig, B.; Jäschke, A. Chem. Biol. 1999, 6, 167-176.
7. Seelig, B.; Keiper, S.; Stuhlmann, F.; Jäschke, A. Angew. Chem., Int. Ed. 2000, 39, 4576-4579.
8. Stuhlmann, F.; Jäschke, A. J. Am. Chem. Soc. 2002, 124, 3238-3244.
9. Keiper, S.; Bebenroth, D.; Seelig, B.; Westhof, E.; Jäschke, A. Chem. Biol. 2004, 11, 1217-1227.
10. Serganov, A.; Keiper, S.; Malinina, L.; Tereshko, V.; Skripkin, E.; Höbartner, C.; Polonskaia, A.; Phan, A. T.; Wombacher, R.; Micura, R.; Dauter, Z.; Jäschke, A.; Patel, D. J. Nat. Struct. Mol. Biol. 2005, 12, 218-224.
11. Jenison, R. D.; Gill, S. C.; Pardi, A.; Polisky, B. Science 1994, 263, 1425-1429.
12. Rational attempts to insert a "universal communication module" (Kertsburg, A.; Soukup, G. A. Nucleic Acids Res. 2002, 30, 4599-4606) led to constructs displaying very low activity both in the presence and in the absence of theophylline (data not shown).
13. Koizumi, M.; Soukup, G. A.; Kerr, J. N.; Breaker, R. R. Nat. Struct. Biol. 1999, 6, 1062-1071.
14. Seelig, B.; Jäschke, A. Bioconjugate Chem. 1999, 10, 371-378.
15. Biotin maleimide and NPM were previously shown to have similar reactivity, in both the catalyzed and the uncatalyzed reaction (see refs 7 and 8).
16. Kovbasyuk, L.; Pritzkow, H.; Krämer, R.; Fritsky, I. O. Chem. Commun. 2004, 880-881.
17. Kovbasyuk, L.; Krämer, R. Chem. Rev. 2004, 104, 3161-3187.
18. Gianneschi, N. C.; Nguyen, S. T.; Mirkin, C. A. J. Am. Chem. Soc. 2005, 127, 1644-1645.