Effects of tidal volume and respiratory frequency on lung lymph flow

Journal of Applied Physiology

Volumn 99, Issue 2, 2005, Pages 556-563

  Pearse, David B ^a,b   Searcy, Robert M ^a   Mitzner, Wayne ^a   Permutt, Solbert ^a   Sylvester, J T ^a  

^a DEPARTMENT OF PATHOLOGY   (United States)

^b Asthma and Allergy Center   (United States)

Author keywords

Edema clearance; Lung fluid balance; Lung interstitial space; Pulmonary edema; Sheep

Indexed keywords

ANIMAL TISSUE; ARTICLE; BREATHING RATE; CONTROLLED STUDY; FILTRATION; FLUID BALANCE; LUNG EDEMA; LUNG INTERSTITIUM; LUNG LYMPH FLOW; LUNG VENTILATION; LYMPH VESSEL; NONHUMAN; PRIORITY JOURNAL; SHEEP; TIDAL VOLUME;

ANIMALS; LUNG; LYMPH; PULMONARY EDEMA; RESPIRATORY MECHANICS; SHEEP; TIDAL VOLUME;

EID: 23044432605     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.00254.2005     Document Type: Article

References (27)

1. Albelda SM, Hansen-Flaschen JH, Lanken PN, and Fishman AP. Effects of increased ventilation on lung lymph flow in unanesthetized sheep. J Appl Physiol 60: 2063-2070, 1986.
2. Bhattacharya J, Gropper MA, and Shepard JM. Lung expansion and the perialveolar interstitial pressure gradient. J Appl Physiol 66: 2600-2605, 1989.
3. Carlton DP, Cummings JJ, Scheerer RG, Poulain FR, and Bland RD. Lung overexpansion increases pulmonary microvascular protein permeability in young lambs. J Appl Physiol 69: 577-583, 1990.
4. Dodd-o JM and Pearse DB. Effect of the NADPH oxidase inhibitor apocynin on ischemia-reperfusion lung injury. Am J Physiol Heart Circ Physiol 279: H303-H312, 2000.
5. Drake R, Adair T, Traber D, and Gabel J. Contamination of caudal mediastinal node efferent lymph in sheep. Am J Physiol Heart Circ Physiol 241: H354-H357, 1981.
6. Drake RE, Laine GA, Allen SJ, Katz J, and Gabel JC. A model of the lung interstitial-lymphatic system. Microvasc Res 34: 96-107, 1987.
7. Dreyfuss D and Saumon G. Ventilator-induced lung injury: lessons from experimental studies. Am J Respir Crit Care Med 157: 294-323, 1998.
8. Gee MH and Donovan KA. The flow and composition of pulmonary and systemic lymph in dogs with edema. Lymphology 12: 125-132, 1979.
9. Gee MH and Havill AM. The relationship between pulmonary perivascular cuff fluid and lung lymph in dogs with edema. Microvasc Res 19: 209-216, 1980.
10. Goshy M, Lai-Fook SJ, and Hyatt RE. Perivascular pressure measurements by wick-catheter technique in isolated dog lobes. J Appl Physiol 46: 950-955, 1979.
11. Hendin AS and Greenspan RH. Ventilatory pumping of human pulmonary lymphatic vessels. Radiology 108: 553-557, 1973.
12. Kambara K, Longworth KE, Serikov VB, and Staub NC. Effect of interstitial edema on lung lymph flow in goats in the absence of filtration. J Appl Physiol 72: 1142-1148, 1992.
13. Koizumi T, Roselli RJ, Parker RE, Hermo-Weiler CI, Banerjee M, and Newman JH. Clearance of filtered fluid from the lung during exercise: role of hyperpnea. Am J Respir Crit Care Med 163: 614-618, 2001.
14. Mackersie RC, Christensen J, and Lewis FR. The role of pulmonary lymphatics in the clearance of hydrostatic pulmonary edema. J Surg Res 43: 495-504, 1987.
15. Miserocchi G, Negrini D, Del Fabbro M, and Venturoli D. Pulmonary interstitial pressure in intact in situ lung: transition to interstitial edema. J Appl Physiol 74: 1171-1177, 1993.
16. Mitzner W and Sylvester JT. Lymph flow and lung weight in isolated sheep lungs. J Appl Physiol 61: 1830-1835, 1986.
17. Patterson GA, Mitzner WA, and Sylvester JT. Assessment of fluid balance in isolated sheep lungs. J Appl Physiol 58: 882-891, 1985.
18. Patterson GA, Rock P, Mitzner WA, Adkinson NF Jr, and Sylvester JT. Effects of imidazole and indomethacin on fluid balance in isolated sheep lungs. J Appl Physiol 58: 892-898, 1985.
19. Pearse DB, Brower RG, Adkinson NF Jr, and Sylvester JT. Spontaneous injury in isolated sheep lungs: role of perfusate leukocytes and platelets. J Appl Physiol 66: 1287-1296, 1989.
20. Pearse DB and Sylvester JT. Vascular injury in isolated sheep lungs. Role of ischemia, extracorporeal perfusion, and oxygen. Am J Respir Crit Care Med 153: 196-202, 1996.
21. Pearse DB, Wagner EM, and Sylvester JT. Edema clearance in isolated sheep lungs. J Appl Physiol 74: 126-132, 1993.
22. Permutt S. Mechanical influences on water accumulation in the lungs. In: Pulmonary Edema, edited by Fishman AP and Renkin EM. Bethesda, MD: Am. Physiol. Soc., 1979, p. 175-193.
23. Sakuma T, Pittet JF, Jayr C, and Matthay MA. Alveolar liquid and protein clearance in the absence of blood flow or ventilation in sheep. J Appl Physiol 74: 176-185, 1993.
24. Tsuno K, Prato P, and Kolobow T. Acute lung injury from mechanical ventilation at moderately high airway pressures. J Appl Physiol 69: 956-961, 1990.
25. Unruh HW, Goldberg HS, and Oppenheimer L. Pulmonary interstitial compartments and tissue resistance to fluid flux. J Appl Physiol 57: 1512-1519, 1984.
26. Warren MF and Drinker CK. The flow of lymph from the lungs of the dog. Am J Physiol 136: 207-221, 1942.
27. Woolverton WC, Brigham KL, and Staub NC. Effect of positive pressure breathing on lung lymph flow and water content in sheep. Circ Res 42: 550-557, 1978.