Gene expression profiling in chemoresistant variants of three cell lines of different origin

Anticancer Research

Volumn 25, Issue 4, 2005, Pages 2661-2668

  Johnsson, Anders ^a   Vallon Christensson, Johan ^a   Strand, Carina ^a   Litman, Thomas ^b   Eriksen, Jens ^b  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

cDNA microarray; Chemotherapy; Gene expression; In vitro; Resistance

Indexed keywords

ABC TRANSPORTER; ABC TRANSPORTER B4; BREAST CANCER RESISTANCE PROTEIN; DAUNORUBICIN; DOXORUBICIN; ETOPOSIDE; HISTONE; MITOXANTRONE; MULTIDRUG RESISTANCE PROTEIN 1; UNCLASSIFIED DRUG; VINCRISTINE;

ARTICLE; CANCER CHEMOTHERAPY; CELL FUNCTION; CLUSTER ANALYSIS; CONTROLLED STUDY; CYTOSTASIS; DNA MICROARRAY; DOWN REGULATION; DRUG SENSITIVITY; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; HUMAN; HUMAN CELL; PHENOTYPE; PRIORITY JOURNAL; UPREGULATION;

BREAST NEOPLASMS; CELL LINE, TUMOR; CLUSTER ANALYSIS; COLONIC NEOPLASMS; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; K562 CELLS; LEUKEMIA, ERYTHROBLASTIC, ACUTE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS;

EID: 22944449354     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Zembutsu H, Ohnishi Y, Tsunoda T, Furukawa Y, Katagiri T, Ueyama Y, Tamaoki N, Nomura T, Kitahara O, Yanagawa R, Hirata K and Nakamura Y: Genome-wide cDNA microarray screening to correlate gene expression profiles with sensitivity of 85 human cancer xenografts to anticancer drugs. Cancer Res 62: 518-527, 2002.
2. Scherf U, Ross D, Waltham M, Smith L, Lee J, Tanabe L, Kohn K, Reinhold W, Myers T, Andrews D, Scudiero D, Eisen M, Sausville E, Pommier Y, Botstein D, Brown P and Weinstein J: A gene expression database for the molecular pharmacology of cancer. Nat Genet 24: 236-244, 2000.
3. Cheok M, Yang W, Pui C, Downing J, Cheng C, Naeve C, Relling M and Evans W: Treatment-specific changes in gene expression discriminate in vivo drug response in human leukemia cells. Nat Genet 34: 85-90, 2003.
4. Sparreboom A, Danesi R, Ando Y, Chan J and Figg W: Pharmacogenomics of ABC transporters and its role in cancer chemotherapy. Drug Resist Update 6: 71-84, 2003.
5. Miyake K, Mickley L, Litman T, Zhan Z, Robey R, Cristensen B, Brangi M, Greenberger L, Dean M, Fojo T and Bates S: Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes. Cancer Res 59: 8-13, 1999.
6. Roed H, Vindelov L, Christensen I, Spang-Thomsen M and Hansen H: The cytotoxic activity of cisplatin, carboplatin and teniposide alone and combined determined on four human small cell lung cancer cell lines by the clonogenic assay. Eur J Cancer Clin Oncol 24: 247-253, 1988.
7. Skehan P, Storeng R, Scudiero D, Monks A, McMahon J, Vistica D, Warren J, Bokesch H, Kenney S and Boyd M: New colorimetric cytotoxicity assay for anticancer-drug screening. J Natl Cancer Inst 82: 1107-1112, 1990.
8. Diatchenko L, Lau YFC, Campbell AP, Chenchik A, Moqadam F, Huang B, Lukyanov S, Lukyanov K, Gurskaya N, Sverdlov ED and Siebert PD: Suppression subtractive hybridization: a method for generating differentially regulated tissue-specific cDNA probes and libraries. Proc Natl Acad Sci USA 93: 6025-6030, 1996.
9. Johnsson A, Zeelenberg I, Min Y, Hilinski J, Berry C, Howell S and Los G: Identification of genes differentially expressed in association with acquired cisplatin resistance. Br J Cancer 83: 1047-1054, 2000.
10. Chomczymski P and Sacchi N: Single step method of RNA isolation by acid guanidium phenol-chloroform extraction. Anal Biochem 162: 156-159, 1987.
11. Saal L, Troein C, Vallon-Christersson J, Gruvberger S, Borg A and Peterson C: BioArray Software Environment (BASE): a platform for comprehensive management and analysis of microarray data. Genome Biol 3: software0003.0001- 0003.0006, 2002.
12. Yang Y, Dudoit S, Luu P, Lin D, Peng V, Ngai J and Speed T: Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation. Nucleic Acids Res 30: e15, 2002.
13. Yang I, Chen E, Hasseman J, Liang W, Frank B, Wang S, Sharov V, Saeed A, White J, Li J, Lee N, Yeatman T and Quackenbush J: Within the fold: assessing differential expression measures and reproducibility in microarray assays. Genome Biol 11: research0062, 2002.
14. Ashburner M, Ball C, Blake J, Botstein D, Butler H, Cherry J, Davis A, Dolinski K, Dwight S, Eppig J, Harris M, Hill D, Issel-Tarver L, Kasarskis A, Lewis S, Matese J, Richardson J, Ringwald M, Rubin G and Sherlock G: Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet 25: 25-29, 2000.
15. Hosack D, Dennis GJ, Sherman B, Lane H and Lempicki R: Identifying biological themes within lists of genes with EASE. Genome Biol 10: R70, 2003.
16. Szakacs G, Annereau J, Lababidi S, Shankavaram U, Arciello A, Bussey K, Reinhold W, Guo Y, Kruh G, Reimers M, Weinstein J and Gottesman M: Predicting drug sensitivity and resistance: profiling ABC transporter genes in cancer cells. Cancer Cell 6: 105-107, 2004.
17. Annereau J, Szakacs G, Tucker C, Arciello A, Cardarelli C, Collins J, Grissom S, Zeeberg B, Reinhold W, Weinstein J, Pommier Y, Paules R and Gottesman M: Analysis of ATP-binding cassette transporter expression in drug-selected cell lines by a microarray dedicated to multidrug resistance. Mol Pharmacol 66: 1397-1405, 2004.
18. Litman T, Druley T, Stein W and Bates S: From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance. Cell Mol Life Sci 58: 931-959, 2001.
19. Turton N, Judah D, Riley J, Davies R, Lipson D, Styles J, Smith A and Gant T: Gene expression and amplification in breast carcinoma cells with intrinsic and acquired doxorubicin resistance. Oncogene 20: 1300-1306, 2001.
20. Belinsky M, Chen Z, Shchaveleva I, Zeng H and Kruh G: Characterization of the drug resistance and transport properties of multidrug resistance protein 6 (MRP6, ABCC6). Cancer Res 62: 6172-6177, 2002.
21. Townsend D and Tew K: Cancer drugs, genetic variation and the glutathione-S-transferase gene family. Am J Pharmacogenomics 3: 157-172, 2003.
22. Theocharis S, Margeli A, Klijanienko J and Kouraklis G: Metallothionein expression in human neoplasia. Histopathology 45: 103-118, 2004.
23. Jarvinen T, Tanner M, Rantanen V, Barlund M, Borg A, Grenman S and Isola J: Amplification and deletion of topoisomerase IIalpha associate with ErbB-2 amplification and affect sensitivity to topoisomerase II inhibitor doxorubicin in breast cancer. Am J Pathol 156: 839-847, 2000.
24. Knuefermann C, Lu Y, Liu B, Jin W, Liang K, Wu L, Schmidt M, Mills G, Mendelsohn J and Fan Z: HER2/PI-3K/Akt activation leads to a multidrug resistance in human breast adenocarcinoma cells. Oncogene 22: 3205-3212, 2003.
25. Kim M, Blake M, Baek J, Kohlhagen G, Pommier Y and Carrier F: Inhibition of histone deacetylase increases cytotoxicity to anticancer drugs targeting DNA. Cancer Res 63: 7291-7300, 2003.
26. Momota H, Ichimiya S, Kondo N, Kikuchi T, Torigoe T, Yamaki T, Houkin K and Sato N: Histone H2AX sensitizes glioma cells to genotoxic stimuli by recruiting DNA double-strand break repair proteins. Int J Oncol 23: 311-315, 2003.
27. Konishi A, Shimizu S, Hirota J, Takao T, Fan Y, Matsuoka Y, Zhang L, Yoneda Y, Fujii Y, Skoultchi A and Tsujimoto Y: Involvement of histone H1.2 in apoptosis induced by DNA double-strand breaks. Cell 114: 655-656, 2003.
28. Lavie Y, Fiucci G and Liscovitch M: Up-regulation of caveolae and caveolar constituents in multidrug-resistant cancer cells. J Biol Chem 273: 32380-32383, 1998.
29. Wang Y, Serfass L, Roy M, Wong J, Bonneau A and Georges E: Annexin-I expression modulates drug resistance in tumor cells. Biochem Biophys Res Commun 314: 565-570, 2004.
30. Wichert A, Stege A, Midorikawa Y, Holm P and Lage H: Glypican-3 is involved in cellular protection against mitoxantrone in gastric carcinoma cells. Oncogene 23: 945-955, 2004.
31. Martin T, Harrison G, Mansel R and Jiang W: The role of the CD44/ezrin complex in cancer metastasis. Crit Rev Oncol Hematol 46: 165-186, 2003.
32. Molinari A, Calcabrini A, Meschini S, Marra M, Stringaro A, Toccacieli L, Cianfriglia M and GA: What is the relationship between P-glycoprotein and adhesion molecule expression in melanoma cells? Melanoma Res 12: 109-114, 2002.