Keynote comment: Nitrosatable drugs, cancer, and guidelines for genotoxicity

Lancet Oncology

Volumn 6, Issue 8, 2005, Pages 538-539

  Brambilla, Giovanni ^a   Martelli, Antonietta ^a  

^a UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDINE; AMINOPHENAZONE; CYANAMIDE; DIMETHYLNITROSAMINE; DRINKING WATER; ETHYLNITROSOUREA; GUANIDINE DERIVATIVE; HYDRAZIDE DERIVATIVE; HYDRAZONE DERIVATIVE; HYDROXYLAMINE; METHYLNITROSOUREA; N NITROSOPROLINE; NITROSAMINE; NITROSO DERIVATIVE; OXYTETRACYCLINE; SODIUM NITRITE; TERTIARY AMINE;

ARTICLE; CANCER; CANCER RESEARCH; CANCER RISK; CARCINOGEN TESTING; CARCINOGENESIS; DIETARY INTAKE; DRUG CARCINOGENICITY; DRUG MEGADOSE; DRUG SCREENING; ENVIRONMENTAL EXPOSURE; GENOTOXICITY; HUMAN; LONG TERM CARE; NITROSATION; PEER REVIEW; PRACTICE GUIDELINE; PRIORITY JOURNAL; RISK ASSESSMENT;

EID: 22944444252     PISSN: 14702045     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1470-2045(05)70257-6     Document Type: Letter

References (5)

1. Müller L Kikuchi Y Probst G et al. ICH harmonized guidances on genotoxicity testing of pharmaceuticals: Evolution, reasoning, and impact Mutat Res 436 1999 195-225
2. Ohshima H H Bartsch Quantitative estimation of endogenous nitrosation in human by monitoring N-nitrosoproline excreted in the urine Cancer Res 41 1981 3658-3662
3. International Agency for Research on Cancer IARC monographs on the evaluation of carcinogenic risks to humans, Supplement 7, overall evaluation of carcinogenicity: An updating of IARC monographs volumes 1 to 42 1987 IARC Lyon 37-74
4. International Agency for Research on Cancer IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol 24, Some Pharmaceutical Drugs 1980 IARC Lyon 297-314
5. G Brambilla E Cajelli R Finollo et al. Formation of DNA-damaging nitroso compounds by interaction of drugs with nitrite. A preliminary screening for detecting potentially hazardous drugs J Toxicol Environ Health 15 1985 1-24