Design, synthesis and growth inhibition activity of bis-epoxyethyl derivatives of stallimycin modified on the amidino moiety

Medicinal Chemistry Research

Volumn 13, Issue 5, 2004, Pages 282-296

  Romagnoli, Romeo ^a   Baraldi, Pier Giovanni ^a   Pavani, Maria Giovanna ^a   Fruttarolo, Francesca ^a   Preti, Delia ^a   Bovero, Andrea ^a   Tabrizi, Mojgan Aghazadhe ^a   Bianchi, Nicoletta ^a   Gambari, Roberto ^a  

^a UNIVERSITY OF FERRARA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDINE; AMIDOXIME; ANTINEOPLASTIC AGENT; AZINOMYCIN A; AZINOMYCIN B; CYANAMIDE; CYANAMIDINE; DISTAMYCIN A DERIVATIVE; EPOXIDE; N [5 [[[5 [[[3 AMINO 3 (CARBAMOYL)ETHYL]AMINO]CARBONYL] 1 METHYL 1H PYRROL 3 YL]AMINO]CARBONYL] 1 METHYL 1H PYRROL 3 YL] 4 BIS(OXIRANYL)AMINO 1 METHYL 1H PYRROLE 2 CARBOXAMIDE; N [5 [[[5 [[[3 AMINO 3 (CYANOIMINO)PROPYL]AMINO]CARBONYL] 1 METHYL 1H PYRROL 3 YL]AMINO]CARBONYL] 1 METHYL 1H PYRROL 3 YL] 4 BIS(OXIRANYL)AMINO 1 METHYL 1H PYRROLE 2 CARBOXAMIDE; N [5 [[[5 [[[3 AMINO 3 (HYDROXYIMINO)PROPYL]AMINO]CARBONYL] 1 METHYL 1H PYRROL 3 YL]AMINO]CARBONYL] 1 METHYL 1H PYRROL 3 YL] 4 BIS(OXIRANYL)AMINO 1 METHYL 1H PYRROLE 2 CARBOXAMIDE; N [5 [[[5 [[[3 AMINO 3 (N METHYLCARBAMOYL)ETHYL]AMINO]CARBONYL] 1 METHYL 1H PYRROL 3 YL]AMINO]CARBONYL] 1 METHYL 1H PYRROL 3 YL] 4 BIS(OXIRANYL)AMINO 1 METHYL 1H PYRROLE 2 CARBOXAMIDE; PLURAMYCIN; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CYTOTOXICITY; DNA ALKYLATION; DRUG ACTIVITY; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; GROWTH INHIBITION; IN VITRO STUDY; LEUKEMIA CELL;

EID: 22944431891     PISSN: 10542523     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00044-004-0034-6     Document Type: Article

References (15)

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