Reduced mitochondrial membrane potential and metabolism correspond to acute chloroform toxicity of in vitro hepatocytes

Journal of Applied Toxicology

Volumn 25, Issue 4, 2005, Pages 310-317

  Hartig, Sean ^a   Fries, Serena ^a,b   Balcarcel, R Robert ^a  

^a VANDERBILT UNIVERSITY   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Chloroform, in vitro hepatocytes; Glucose uptake; Lactate production; Metabolic rate screening; Mitochondrial membrane potential; Well plate

Indexed keywords

CHLOROFORM; CYTOCHROME P450; DRINKING WATER; GLUCOSE; LACTIC ACID; PHOSGENE; RHODAMINE 123;

AMBIENT AIR; ANIMAL CELL; APOPTOSIS; ARTICLE; BIOTRANSFORMATION; CARCINOGENICITY; CELL DEATH; CELL VIABILITY; CHLORINATION; CONCENTRATION RESPONSE; GLUCOSE INTAKE; LIVER CELL; LIVER METABOLISM; LIVER MITOCHONDRION; MEMBRANE POTENTIAL; METABOLIC RATE; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RISK ASSESSMENT;

ANIMALS; APOPTOSIS; CELL LINE; CELL SURVIVAL; CHLOROFORM; GLUCOSE; HEPATOCYTES; KINETICS; LACTIC ACID; MEMBRANE POTENTIALS; MICE; MITOCHONDRIA, LIVER; RHODAMINE 123;

EID: 22844442333     PISSN: 0260437X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jat.1067     Document Type: Article

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