The effect of phenytoin on rocuronium-induced neuromuscular block in the rat phrenic nerve-hemidiaphragm preparation

Journal of Neurosurgical Anesthesiology

Volumn 17, Issue 3, 2005, Pages 149-152

  Kim, Joung Uk ^a   Lee, Yoon Kyung ^a   Lee, Yu Mi ^a   Yang, Hyun Ok ^a   Han, Sung Min ^a   Yang, Hong Seuk ^a  

^a University of Ulsan College of Medicine   (South Korea)

Author keywords

Drug interaction; Neuromuscular relaxant; Phenytoin; Rocuronium

Indexed keywords

PHENYTOIN; ROCURONIUM; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT THERAPY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENTIATION; HEMIDIAPHRAGM; MALE; MUSCLE TWITCH; NERVE STIMULATION; NEUROMUSCULAR BLOCKING; NONHUMAN; PHRENIC NERVE; PRIORITY JOURNAL; RAT;

ANDROSTANOLS; ANIMALS; DIAPHRAGM; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; MALE; MUSCLE RELAXANTS, CENTRAL; NEUROMUSCULAR NONDEPOLARIZING AGENTS; NONLINEAR DYNAMICS; PHENYTOIN; PHRENIC NERVE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 22844432386     PISSN: 08984921     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ana.0000171732.18138.ce     Document Type: Article

References (21)

1. Martyn JA, White DA, Gronert GA, et al. Up-and-down regulation of skeletal muscle acetylcholine receptors: Effects on neuromuscular blockers. Anesthesiology. 1992;76:822-843.
2. Gray HS, Slater RM, Pollard BJ. The effect of acutely administered phenytoin on vecuronium-induced neuromuscular blockade. Anaesthesia. 1989;44:379-381.
3. Alloul K, Whalley DG, Shutway F, et al. Pharmacokinetic origin of carbamazepine-induced resistance to vecuronium neuromuscular blockade in anesthetized patients. Anesthesiology. 1996;84:330-339.
4. Hickey DR, Sangwan S, Bevan JC. Phenytoin-induced resistance to pancuronium. Use of atracurium infusion in management of a neurosurgical patient. Anaesthesia. 1988;43:757-759.
5. Spacek A, Nickl S, Neiger FX, et al. Augmentation of the rocuronium-induced neuromuscular block by the acutely administered phenytoin. Anesthesiology. 1999;90:1551-1555.
6. Soriano SG, Kaus SJ, Sullivan LJ, et al. Onset and duration of action of rocuronium in children receiving chronic anticonvulsant therapy. Paediatr Anaesth. 2000;10:133-136.
7. Soriano SG, Sullivan LJ, Venkatakrishnan K, et al. Pharmacokinetics and pharmacodynamics of vecuronium in children receiving phenytoin or carbamazepine for chronic anticonvulsant therapy. Br J Anaesth. 2001;86:223-229.
8. Viby-Mogensen J, Engbaek J, Eriksson LI, et al. Good clinical research practice in pharmacodynamic studies of neuromuscular blocking agents. Acta Anaesthesiol Scand. 1996;40:59-74.
9. Yaari Y, Pincus JH, Argov Z. Phenytoin and transmitter release at the neuromuscular junction of the frog. Brain Res. 1979;160:479-487.
10. Raines A, Standaert FG. Pre- and postjunctional effects of diphenylhydantoin at the cat soleus neuromuscular junction. J Pharmacol Exp Ther. 1966;153:361-366.
11. Gage PW, Lonergan M, Torda TA. Presynaptic and postsynaptic depressant effects of phenytoin sodium at the neuromuscular junction. Br J Pharmacol. 1980;69:119-121.
12. Platt PR, Thackray NM. Phenytoin-induced resistance to vecuronium. Anaesth Intensive Care. 1993;21:185-191.
13. Liberman BA, Norman P, Hardy BG. Pancuronium-phenytoin interaction: a case of decreased duration of neuromuscular blockade. Int J Clin Pharmacol Ther Toxicol. 1988;26:371-374.
14. Ornstein E, Matteo RS, Weinstein JA, et al. Accelerated recovery from doxacurium-induced neuromuscular blockade in patients receiving chronic anticonvulsant therapy. J Clin Anesth. 1991;3:108-111.
15. Jellish WS, Modica PA, Tempelhoff R. Accelerated recovery from pipecuronium in patients treated with chronic anticonvulsant therapy. J Clin Anesth. 1993;5:105-108.
16. Ornstein E, Matteo RS, Young WL, et al. Resistance to metocurine-induced neuromuscular blockade in patients receiving phenytoin. Anesthesiology. 1985;63:294-298.
17. Tempelhoff R, Modica PA, Jellish WS, et al. Resistance to atracurium-induced neuromuscular blockade in patients with intractable seizure disorders treated with anticonvulsants. Anesth Analg. 1990;71:665-669.
18. Nation RL, Evans AM, Milne RW Pharmacokinetic drug interactions with phenytoin (Part II). Clin Pharmacokinet. 1990;18:131-150.
19. Pirrtiaho HI, Sotaniemi EA, Pelkonen RO, et al. Hepatic blood flow and drug metabolism in patients on enzyme-inducing anticonvulsants. Eur J Clin Pharmacol. 1982;22:441-445.
20. Kim CS, Arnold FJ, Itani MS, et al. Decreased sensitivity to metocurine during long-term phenytoin therapy may be attributable to protein binding and acetylcholine receptor changes. Anesthesiology. 1992;77:500-506.
21. Winter ME. Basic Clinical Pharmacokinetics, 2nd ed. Spokane, WA: Applied Therapeutics, 1988:235-264.