Shigella flexneri infection is dependent on villin in the mouse intestine and in primary cultures of intestinal epithelial cells

Cellular Microbiology

Volumn 7, Issue 8, 2005, Pages 1109-1116

  Athman, Rafika ^a   Fernandez, Maria Isabel ^b   Gounon, Pierre ^c   Sansonetti, Philippe ^b   Louvard, Daniel ^a   Philpott, Dana ^b   Robine, Sylvie ^a  

^a INSTITUT CURIE   (France)

^b INSTITUT PASTEUR   (France)

^c INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN BINDING PROTEIN; CALCIUM ION; F ACTIN; VILLIN;

ACTIN FILAMENT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SPREADING; CONTROLLED STUDY; CYTOSKELETON; ENTERITIS; INTESTINE CELL; INTESTINE EPITHELIUM; KNOCKOUT MOUSE; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHIGELLA FLEXNERI; SHIGELLOSIS;

ACTINS; ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; CYTOSKELETON; DYSENTERY, BACILLARY; EPITHELIAL CELLS; INTESTINAL MUCOSA; INTESTINES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROFILAMENT PROTEINS; MICROSCOPY, ELECTRON, TRANSMISSION; SHIGELLA FLEXNERI;

SHIGELLA; SHIGELLA FLEXNERI;

EID: 22744458471     PISSN: 14625814     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1462-5822.2005.00535.x     Document Type: Article

References (17)

1. Adam, T., Arpin, M., Prevost, M.C., Gounon, P., and Sansonetti, P.J. (1995) Cytoskeletal rearrangements and the functional role of T-plastin during entry of Shigella flexneri into HeLa cells. J Cell Biol 129: 367-381.
2. Athman, R., Louvard, D., and Robine, S. (2002a) The epithelial cell cytoskeleton and intracellular trafficking. III. How is villin involved in the actin cytoskeleton dynamics in intestinal cells? Am J Physiol Gastrointest Liver Physiol 283: G496-G502.
3. Athman, R.J., Niewohner, D., Louvard and Robine (2002b) Epithelial cells: establishment of primary cultures and immortalization. In Methods in Microbiology, Vol. 31. Sansonetti, P., Zychlinsky, A. (eds). London: Academic Press, pp. 93-113.
4. Athman, R., Louvard, D., and Robine, S. (2003) Villin enhances HGF-induced actin cytoskeleton remodeling in epithelial cells. Mol Biol Cell 14: 4641-4653.
5. Bernardini, M.L., Mounier, J., d'Hauteville, H., Coquis-Rondon, M., and Sansonetti, P.J. (1989) Identification of icsA, a plasmid locus of Shigella flexneri that governs bacterial intra- and intercellular spread through interaction with F-actin. Proc Natl Acad Sci USA 86: 3867-3871.
6. Dudouet, B., Robine, S., Huet, C., Sahuquillo-Merino, C., Blair, L., Coudrier, E., and Louvard, D. (1987) Changes in villin synthesis and subcellular distribution during intestinal differentiation of HT29-18 clones. J Cell Biol 105: 359-369.
7. Evans, G.S., Flint, N., Somers, A.S., Eyden, B., and Potten, C.S. (1992) The development of a method for the preparation of rat intestinal epithelial cell primary cultures. J Cell Sci 101: 219-231.
8. Fernandez, M.I., Thuizat, A., Pedron, T., Neutra, M., Phalipon, A., and Sansonetti, P.J. (2003) A newborn mouse model for the study of intestinal pathogenesis of shigellosis. Cell Microbiol 5: 481-491.
9. 2+ dependent F-actin disruption in intestinal brush-borders. J Cell Biol 146: 819-829.
10. Formal, S.B., Kent, T.H., May, H.C., Palmer, A., Falkow, S., and LaBrec, E.H. (1966) Protection of monkeys against experimental shigellosis with a living attenuated oral polyvalent dysentery vaccine. J Bacteriol 92: 17-22.
11. Kent, T.H., Formal, S.B., LaBrec, E.H., Sprinz, H., and Maenza, R.M. (1967) Gastric shigellosis in rhesus monkeys. Am J Pathol 51: 259-267.
12. Laurent, V., Loisel, T.P., Harbeck, B., Wehman, A., Grobe, L., Jockusch, B.M., et al. (1999) Role of proteins of the Ena/VASP family in actin-based motility of Listeria monocytogenes. J Cell Biol 144: 1245-1258.
13. Mathan, M.M., and Mathan, V.I. (1991) Morphology of rectal mucosa of patients with shigellosis. Rev Infect Dis 13: S314-S318.
14. Rathman, M., de Lanerolle, P., Ohayon, H., Gounon, P., and Sansonetti, P. (2000) Myosin light chain kinase plays an essential role in S. flexneri dissemination. J Cell Sci 113: 3375-3386.
15. Skoudy, A., Nhieu, G.T., Mantis, N., Arpin, M., Mounier, J., Gounon, P., and Sansonetti, P. (1999) A functional role for ezrin during Shigella flexneri entry into epithelial cells. J Cell Sci 112: 2059-2068.
16. Tran Van Nhieu, G., Clair, C., Bruzzone, R., Mesnil, M., Sansonetti, P., and Combettes, L. (2003) Connexin-dependent inter-cellular communication increases invasion and dissemination of Shigella in epithelial cells. Nat Cell Biol 5: 720-726.
17. Zhai, L., Zhao, P., Panebra, A., Guerrerio, A.L., and Khurana, S. (2001) Tyrosine phosphorylation of villin regulates the organization of the actin cytoskeleton. J Biol Chem 276: 36163-36167.