Clinical evaluation of ophthalmic lomefloxacin 0.3% in comparison with fortified cefazolin and gentamicin ophthalmic solutions in the treatment of presumed bacterial keratitis

Journal of the Medical Association of Thailand

Volumn 87, Issue SUPPL. 2, 2004, Pages

  Erjongmanee, Suphawadee ^a   Kasetsuwan, Ngamjit ^a   Phusitphoykai, Nutharin ^a   Puangsricharern, Vilavun ^a   Pariyakanok, Lalida ^a  

^a CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

Bacterial Keratitis; Cefazolin; Gentamicin; Lomefloxacin

Indexed keywords

CEFAZOLIN; GENTAMICIN; LOMEFLOXACIN;

ADOLESCENT; ADULT; ARTICLE; BACTERIAL INFECTION; BACTERIAL KERATITIS; BACTERIUM CULTURE; CLINICAL ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG SAFETY; DRUG TOLERABILITY; EPITHELIZATION; FEMALE; HUMAN; KERATITIS; MALE; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL;

ACUTE DISEASE; ADOLESCENT; ADULT; ANTI-BACTERIAL AGENTS; CEFAZOLIN; DOUBLE-BLIND METHOD; FEMALE; FLUOROQUINOLONES; GENTAMICINS; HUMANS; KERATITIS; MALE; OPHTHALMIC SOLUTIONS; PROSPECTIVE STUDIES; QUINOLONES;

EID: 22744454811     PISSN: 01252208     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Yospaiboon Y, Prabriputaloong A. Ulcerative keratitis. Rama Med J 1986;9:23-9.
2. Kunavisrut S, Prawingwongwuth K, Sirimongkolkasem A. Corneal ulcer: clinical analysis of 60 cases. Rama Med J 1989;12:122-6.
3. Pariyakanok L, Rojanapongpun P, Kittipibul T. Non-herpetic microbial corneal ulcer: a prospective study (demographic part). Chula Med J 1991;35:71-82.
4. Kosrirukvong P, Prabhasawat P, Kumavibhat P. Corneal ulcer at Siriraj Hospital. Siriraj Hosp Gaz 1992;44:856-7.
5. Boonpasart S, Kasetsuwan N, Puangsricharern V, Pariyakanok L, Jittpoonkuso T. Infectious keratitis at King Chulalongkorn Memorial Hospital: A 12 year retrospective study of 391 cases. J Med Assoc Thai 2002;85:217-30.
6. Baum JL, Barza M, Weinstein L. Preferred route of antibiotic administration and treatment of bacterial ulcers of the cornea. Intophthalmol Clin. 1973;13:31-7.
7. Matoba AY. Infectious Keratitis. Focal Points. Clinical Modules for Ophthalmologists 1992;10:1-12.
8. McDonnell PJ. Empirical or culture-guided therapy for microbial keratitis? A plea for data. Arch Ophthalmol 1996;114:84-7.
9. Bowe BE, Levartovsky S, Eiferman RA. Neurotrophic corneal ulcers in congenital sensory neuropathy. Am J Ophthalmol 1989;107:303-4.
10. Parks DI0J, Abrams DA, Sarfarazi FA, et al. Comparison of topical ciprofloxacin to conventional antibiotic therapy in the treatment of ulcerative keratitis. Am J Ophthalmol 1993;115:471-7.
11. Uchida Y. Clinical efficacy of topical lomefloxacin in bacterial infections of the external eye. Folia Ophthalmol Jpn 1991;42:52-70.
12. Wadworth AN, Goa KL. Lomefloxacin - a review of its antibacterial activity, pharmacokinetic properties, and therapeutic use. Drugs 1991;42:1018-60.
13. Wolfson JS, Hooper DC. The fluoroquinolone: structures, mechanism of action and resistance, and spectrum of activity in vitro. Antimicrob Agents Chemother 1985; 28:581-6.
14. O'Brien TP, Sawusch M, Dick JD, Gottsch JD. Topical ciprofloxacin treatment of Pseudomonas-keratitis in rabbits. Arch Ophthalmol 1988;106:1444-6.
15. Malminiemi K, Kari O, Latvala ML, et al. Topical lomefloxacin twice daily compared with fusidic acid in acute bacterial conjunctivitis. Acta Ophthalmol 1996; 74:280-4.
16. Agius-Fernandez A, Patterson A, Fsadni M, et al. Topical lomefloxacin versus topical chloramphenicol in the treatment of acute bacterial conjunctivitis. Clin drug Invest 1998;15:263-9.
17. Gallenga PE, Lobefalo L, Colangelo L, et al. Topical lomefloxacin 0.3% twice daily versus tobramycin 0.3% in acute bacterial conjunctivitis: A multicenter double-blind phase III study. Ophthalmologica 1999;213:250-7.
18. Montero J, Casado A, Perea E, at al. A double-blind double-dummy comparison of omefloxacin 0.3% twice daily with topical gentamicin 0.3% four times daily in the treatment of acute bacterial conjunctivitis. Journal of Clinical Research 1998;1:29-39.
19. Malminiemi K, Kari O, Latval M-L, et al. Topical lomefloxacin twice daily compared with fucidic acid in acute bacterial conjunctivitis. Acta Ophthalmol 1996;74:280-4.
20. Baum JL, Jones DB. Initial therapy of suspected microbial corneal ulcer, I: board antibiotic therapy based on prevalence of organisms, II: specific antibiotic therapy based on corneal smear. Surv Ophthalmol 1979;24:97-116.
21. Barry AL, Jones RN. In vitro activity of ciprofloxacin against gram positive cocci. Am L Med 1987;82(suppl): 27-32.
22. Chin NX, Neu HC. Post antibiotic suppressive effect of ciprofloxacin against gram negative bacteria. Am J Med 1987;82 (suppl):58-62.
23. Smith SM, Eng RH. Activity of ciprofloxacin against methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother 1985;27:688-91.
24. Leibowitz HM. Antibacterial effectiveness of ciprofloxacin 0.3% ophthalmic solution in the treatment of bacterial conjunctivitis. Am J Ophthalmol 1993;12(suppl):S29-33.
25. Leibowitz HM. Clinical evaluation of ciprofloxacin 0.3% ophthalmic solution for the treatment of bacterial keratitis. Am J Ophthalmol 1991;112:S34-47.
26. Insler MS, Fish LA, Silbernagel J, Hobden JA, O'Callaghan RJ, Hill JM. Successful treatment of methicillin-resistant Staphylococcus aureus keratitis with topical ciprofloxacin. Ophthalmology 1991;98:1690.
27. Parks DJ, Abrams DA, Sarfarazi FA, Katz HR. Comparison of topical ciprofloxacin to conventional antibiotic therapy in the treatment of ulcerative keratitis. Am J Oph 1993;115:471-7.
28. O'Brien TP, Maguire MG, Fink NE, et al. Efficacy of ofloxacin versus cefazolin and tobramycin in the therapy of bacterial keratitis. Arch Ophthalmol 1995;113:1257-65.
29. Kunimoto DY, Sharma S, Garg P, et al. In vitro susceptibility of bacterial keratitis pathogens to ciprofloxacin. Emerging resistance. Ophthalmology 1999;106:80-5.
30. Snyder ME, Katz HR. Ciprofloxacin-resistant bacterial keratitis. Am J Ophthalmol 1992;114:336-8.
31. Maffett M, O'day DM. Ciprofloxacin-resistant bacterial keratitis [letter]. Am J Ophthalmol 1993;115:545-6.
32. Goldstein MH, Kowalski RP, Gordon J. Emerging fluoroquinolone resistance in bacterial keratitis. Ophthalmology 1999;106:1313-8.
33. Malet F, Colin J, Jauch A, Abalain M. Bacterial keratitis therapy in guinea pigs with lomefloxacin by initially high followed by low dosage regimen. Ophthalmic Res 1995;27:322-9.
34. Jauch A, Fsadni MG, Gamba G. Meta-analysis of six clinical Phase III studies comparing lomefloxacin 0.3% eye drops twice daily to five standard antibiotics in patients with acute bacterial conjunctivitis. Graefes Arch clin Exp Ophthalmol 1999;237:705-13.
35. Hirose T, Mitsuhashi S, Inoue M. In vitro and in vivo antibacterial activities of NY-198. Chemotherapy (Tokyo) 1988;36:1-24.
36. Elena PP, Jauch A. Ocular distribution of lomefloxacin 0.3% after a single instillation in the infected eye of pigmented rabbits. J Ocul Pharmacol Ther 1997;13:551-8.
37. Ooishi M, Oomomo A, Sakaue F, et al. Studies on intraocular penetration of lomefloxacin eye drops. Acta soc Ophthalmol Jpn 1988;92:1825-32.
38. Sasaki K, Mitsui Y, Fukuda M, et al. Intraocular penetration mode of five fluoroquinolone ophthalmic solutions evaluated by the newly proposed parameter. Atarashii Ganka (Journal of the Eye) 1995;12:787-90.
39. Kodama T. Penetration of lomefloxacin ophthalmic solution into the human aqueous humor. J Jpn Rev Ophthalmol 1991;85:493-5.
40. Fukuda M, Chou JS, Sasaki K. Intraocular dynamics of a new antibacterial derivative of pyridone carboxylic acid (NY-198). Folia Ophthalmol Jpn 1989;40:72-6.
41. Hatano H, Inoue K, Shia S, Liping W. Application of topical lomefloxacin against experimental Pseudomonas endophthalmitis in rabbits. Acta Ophthalmol 1993;71: 666-70.
42. Velpandian T, Gupta SK, Gupta YK, Agrawal HC, Biswas NR. Comparative studies on topical lomefloxacin and ciprofloxacin on ocular kinetic and experimental corneal ulcer. J Ocul Pharmacol Ther 1999;15:505-11.
43. Karp CL, Forster RK. The Cornea Ulcer. In: Krachmer JH, Mannis MJ, and Holland EJ, eds Cornea, St Louis: Mosby; 1997:403-8.
44. nd ed. Philadelphia: Saunder 1998:613-43.