Bosentan, the mixed ETA-ETB endothelin receptor antagonist, attenuated oxidative stress after experimental myocardial ischemia and reperfusion

Molecular and Cellular Biochemistry

Volumn 275, Issue 1-2, 2005, Pages 67-74

  Gupta, Suresh K ^a   Saxena, Amit ^a   Singh, Uma ^a   Arya, Dharamvir S ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Bosentan; Cardioprotection; Endothelin; Myocardial ischemia reperfusion; Oxidative stress

Indexed keywords

BOSENTAN; CATALASE; ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR ANTAGONIST; ENDOTHELIN B RECEPTOR; ENDOTHELIN B RECEPTOR ANTAGONIST; GLUTATHIONE; MALONALDEHYDE; SODIUM CHLORIDE; SUPEROXIDE DISMUTASE; CARDIOTONIC AGENT; ENDOTHELIN RECEPTOR; SULFONAMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVITY; HEART CONTRACTION; HEART HEMODYNAMICS; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HEART RATE; HISTOPATHOLOGY; LEFT ANTERIOR DESCENDING CORONARY ARTERY; LIPID PEROXIDATION; MALE; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; RAT; REPERFUSION INJURY; STATISTICAL SIGNIFICANCE; ANIMAL; CHEMISTRY; COMPARATIVE STUDY; DRUG ANTAGONISM; DRUG EFFECT; HEART MUSCLE; METABOLISM; WISTAR RAT;

ANIMALIA; RATTUS NORVEGICUS;

ANIMALS; CARDIOTONIC AGENTS; CATALASE; GLUTATHIONE; MALE; MALONDIALDEHYDE; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; OXIDATIVE STRESS; RATS; RATS, WISTAR; RECEPTORS, ENDOTHELIN; SULFONAMIDES; SUPEROXIDE DISMUTASE;

EID: 22744440541     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11010-005-1999-2     Document Type: Article

References (57)

1. Weber KT, Janicki JS: The metabolic demand and oxygen supply of the heart: Physiologic and clinical considerations. Am J Cardiol 44: 722-729, 1979
2. Hearse DJ: Ischemia, reperfusion and the determinants of tissue injury. Cardiovasc Drug Ther 4: 767-776, 1990
3. Harden WR, Barlow CH, Simson MB, Harken AH: Myocardial ischemia and left ventricular failure in the isolated perfused rabbit heart. Am J Cardiol 44: 741-746, 1979
4. ISIS-2. Randomised trial of intravenous streptokinase, oral aspirin, both or neither among 17187 cases of suspected acute myocardial infarction. Lancet 2: 349-360, 1988
5. Zijlstra F, Patel A, Jones M, et al.: Clinical characteristics and outcome of patients with early (< 2 h), intermediate (2-4 h) and late (> 4 h) presentation treated by primary coronary angioplasty or thrombolytic therapy for acute myocardial infarction. Eur Heart J 23: 550-557, 2002
6. Kloner RA, Ellis SG, Lange R, Braunwald E: Studies of experimental coronary artery reperfusion: Effects on infarct size, myocardial function, biochemistry, ultrastructure and microvascular damage. Circulation 68: I8-I15, 1983
7. Braunwald E, Kloner RA: Myocardial reperfusion: A double-edged sword. J Clin Invest 76: 1713-1719, 1985
8. Reimer KA, Heide RSV, Pichard VJ: Reperfusion in acute myocardial infarction: Effect of timing and modulating factors in experimental models. Am J Cardiol 72: 13-21, 1993
9. RM Temsah T Netticadan NS Dhalla 2003 Mechanisms of cellular alterations due to ischemia-reperfusion injury in the heart In: N.S. Dhalla N. Takeda M. Singh A. Lukas (eds). Myocardial Ischemia and Preconditioning Kluwer Academic Publishers Boston 149-164
10. Bolli R, Marban E: Molecular and cellular mechanism in myocardial stunning. Physiol Rev 79: 609-634, 1999
11. Grech ED, Bellamy CM, Jackson MJ, Miurhead RA, Faragher EB, Ramsdale DR: Free radical activity after primary coronary angioplasty in acute myocardial infarction. Am Heart J 127: 1443-1449, 1994
12. Diaz-Araya G, Nettle D, Castro P, Miranda F, Greig D, Campos X, Chiong M, Nazzal C, Carbalan R, Lavandero S: Oxidative stress after reperfusion with primary coronary angioplasty: Lack of effect of glucose-insulin-potassium infusion. Crit Care Med 30: 417-421, 2002
13. Dhalla NS, Panagia V, Singal PK, Makino N, Dixon IM, Eyolfson DA: Alterations in heart membrane calcium transport during the development of ischemia-reperfusion injury. J Mol Cell Cardiol 20 (suppl 2): 3-13, 1988
14. 2+ overload in reperfused myocardium. Annu Rev Physiol 52: 543-559, 1990
15. Ceconi C, Curello S, Cargnoni A, Ferrari R, Albertini A, Visioli O: The role of glutathione status in the protection against ischaemic and reperfusion damage: Effects of N-acetyl cysteine. J Mol Cell Cardiol 20: 5-13, 1988
16. Goldhaber JL, Weiss JN: Oxygen free radicals and cardiac reperfusion abnormalities. Hypertension 20: 118-127, 1992
17. Ferrari R, Alfieri O, Curello S, Ceconi C, Cargnoni A, Marzollo P, Pardini A, Gaurnieri C, Visioli O: Occurrence of oxidative stress during reperfusion of the human heart. Circulation 81: 201-211, 1990
18. Dauber IM, Lesnefsky EJ, VanBenthuysen KM, Weil JV, Horwitz LD: Reactive oxygen metabolite scavengers decrease functional coronary microvascular injury due to ischemia-reperfusion. Am J Physiol 260: H 42-H 49, 1991
19. Ferrari R, Ceconi C, Curello S, Cargnoni A, Alfieri O, Pardini A, Marzollo P, Visioli O: Oxygen free radicals and myocardial damage: Protection with thiol containing agents. Am J Med 91: S 95-S 105, 1991
20. Jolly SR, Kane WJ, Bailie WB, Abrams GD, Lucchesi BR: Canine myocardial reperfusion injury: Its reduction by combined administration of superoxide dismutase and catalase. Circ Res 54: 227-285, 1984
21. Otani H, Engelman RM, Rousou JA, Breyer RH, Lemeshow S, Das DK: Cardiac performance during reperfusion improved by pretreatment with oxygen free-radical scavengers. J Thorac Cardiovasc Surg 91: 290-295, 1986
22. Nnslund U, Hnggmark S, Johansson G, Marklund SL, Reiz S: Limitation of myocardial infarct size by superoxide dismutase as an adjunct to reperfusion after different durations of coronary occlusion in pig. Circ Res 66: 1294-1301, 1990
23. Dhalla NS, Elmoselhi AB, Hata T, Makino N: Status of myocardial antioxidants in ischemia-reperfusion injury. Cardiovasc Res 47: 446-456, 2000
24. Grover GJ, Sleph PG, Fox M, Trippodo NC: Role of endothelin-1 and big endothelin-1 in modulating coronary vascular tone, contractile function and severity of ischemia in rat hearts. J Pharmacol Exptl Ther 263: 1074-1082, 1992
25. Yanagisawa M, Kurihara H, Kimura S, Goto K, Masaki T: A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 332: 411-415, 1988
26. Clozel JP, Clozel M: Effects of endothelin on the coronary vascular bed in open-chest dogs. Circ Res 65: 1193-1200, 1989
27. Toyo-oka T, Aizawa T, Suzuki N, Hirata Y, Miyauchi T, Shin WS, Yanagisawa M, Masaki T, Suginoto T: Increased plasma level of endothelin-1 and coronary spasm induction in patients with vasospastic angina pectoris. Circulation 83: 476-483, 1991
28. Nakao K, Saito Y, Matsuyama K, Okumura K, Jougasaki M, Yasue H: Implication of endothelin in variant angina. Circulation 80: II-586, 1989
29. Matsuyama K, Saito Y, Nakao K, Jougasaki M, Okumara K, Yasue H, Imura H: Endothelin in myocardial ischemia induced by coronary spasm. Circulation 83: III-443, 1990
30. Wei CM, Lerman A, Rodeheffer RJ: Endothelin in human congestive heart failure. Circulation 89: 1580-1586, 1994
31. Watanabe T, Suzuki N, Shimamoto N, Fujino M, Imada A: Contribution of endogenous endothelin to the extension of myocardial infarct size in rats. Circ Res 69: 370-377, 1991
32. Kusumoto K, Awane Y, Fujiwara S, Watanabe T: Role of endogenous endothelin in extension of rabbit myocardial infarction. J Cardiovasc Pharmacol 22 (suppl 8): S 339-S 342, 1993
33. Wang Q-D, Li X-S, Lundberg JM, Pernow J: Protective effects of non-peptide endothelin receptor antagonist bosentan on myocardial ischaemic and reperfusion injury in the pig. Cardiovasc Res 29: 805-812, 1995
34. Li X-S, Wang Q-D, Pernow J: Beneficial effects of the endothelin receptor antagonist bosentan on myocardial and endothelial injury following ischemia/reperfusion in the rat. Eur J Pharmacol 283: 161-168, 1995
35. Grover GJ, Dzwonczyk S, Parham CS: The endothelin-1 receptor antagonist B-Q 123 reduces infarct size in a canine model of coronary occlusion and reperfusion. Cardiovasc Res 27: 1613-1618, 1993
36. B antagonist. Br J Pharmacol 113, 869-876, 1994
37. Krause SM, Lynch JJ, Stabilito II, Woltmann RF: Intravenous administration of the endothelin-1 antagonist BQ-123 does not ameliorate myocardial ischaemic injury following acute coronary artery occlusion in the dog. Cardiovasc Res 28: 1672-1678, 1994
38. A receptor antagonist, FR 139317, on infarct size in a rabbit model of acute myocardial ischaemia and reperfusion. Br J Pharmacol 112: 75-80, 1994
39. Ohkawa H, Ohishi N, Yagi K: Assay of lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95: 351-358, 1979
40. Maron MS, Depierre JW, Mannervik B: Levels of glutathione, glutathione reductase and glutathione-s-transferase activities in rat lung and liver. Biochem Biophys Acta 82: 67-78, 1979
41. Misra HP, Fridovich I: The role of superoxide anion in the autooxidation of epinephrine and a simple assay of superoxide dismutase. J Biol Chem 247: 3170-3175, 1972
42. H Aebi 1974 Catalase In: H.U. Bergmeyer (ed). Methods in Enzymatic Analysis, Vol. 2 Academic Press New York 674-684
43. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ: Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-275, 1951
44. PS Tappia G Asemu NS Dhalla 2003 Phospholipase C-mediated signaling in ischemic heart disease In: N.S. Dhalla N. Takeda M. Singh A. Lukas (eds). Myocardial Ischemia and Preconditioning Kluwer Academic Publishers Boston 83-93
45. Krishenbaum LA, Singal PK: Increase in endogenous antioxidant enzymes protects hearts against reperfusion injury. Am J Physiol 265: H 484-H 493, 1993
46. Vergely C, Perrin C, Laubriet A, Oudot A, Zeller M, Guilland J-C, Rochette L: Postischemic myocardial recovery and oxidative stress status of vitamin C deficient rat hearts. Cardiovasc Res 51: 89-99, 2001
47. Blasig IE, Shuter S, Garlick P, Slater T: Relative time-profiles for free radical trapping, coronary flow, enzyme leakage, arrhythmias and function during myocardial reperfusion. Free Radic Biol Med 16: 35-41, 1994
48. Kloner RA, Przyklenk K, Whittaker P: Deleterious effects of oxygen radicals in ischemia/reperfusion: Resolved and unresolved issues. Circulation 80: 1115-1127, 1989
49. De Keulenaer GW, Andries LJ, Sys SU, Bretsaert DL: Endothelin-mediated positive inotropic effect induced by reactive oxygen species in isolated cardiac muscle. Cir Res 76: 878-784, 1995
50. Kahler J, Mendel S, Weckmuller J, Orzechowski HD, Mittmann C, Koster R, Paul M, Meinertz T, Munzel T: Oxidative stress increases synthesis of big endothelin-1 by activation of the endothelin-1 promoter. J Mol Cell Cardiol 32: 1429-1437, 2000
51. Leichtweis S, Ji LL: Glutathione deficiency intensifies ischaemia-reperfusion induced cardiac dysfunction and oxidative stress. Acta Physiol Scand 172: 1-10, 2001
52. Ceconi C, Cargnoni A, Pasini E, Condorelli E, Curello S, Ferrari R: Evaluation of phospholipid peroxidation as malondialdehyde during myocardial ischemia and reperfusion injury. Am J Physiol 260: H 1057-H 1061, 1991
53. Werns SW, Fantone JC, Ventura A, Lucchesi BR: Myocardial glutathione depletion impairs recovery of isolated blood perfused hearts after global ischaemia. J Mol Cell Cardiol 24: 1215-1220, 1992
54. Gao F, Yao C-L, Gao E, Mo Q-Z, Yan W-L, McLaughlin R, Lopez BL, Christopher TA, Ma XL: Enhancement of glutathione cardioprotection by ascorbic acid in myocardial reperfusion injury. J Pharmacol Exp Ther 301: 543-550, 2002
55. Richard VJ, Murry CE, Jennings RB, Reimer KA: Superoxide dismutase and catalase do not limit infarct size after 90 minutes of ischemia and 4 days of reperfusion in dogs. Circulation 76(suppl IV): IV-199, 1987
56. Gallagher KP, Buda AJ, Pace D, Gerren RA, Schlafer M: Failure of superoxide dismutase and catalase to alter infarct size in conscious dogs after 3 hours of occlusion followed by reperfusion. Circulation 73: 1065-1076, 1986
57. Ishida K, Takeshige K, Minakami S: Endothelin-1 enhances superoxide generation of human neutrophils stimulated by the chemotactic peptide N-formyl-methionyl-leucyl-phenylalanine. Biochem Biophys Res Commun 173: 496-500, 1990