Evaluation of antidiarrheal potential of Emblica officinalis

Pharmaceutical Biology

Volumn 43, Issue 4, 2005, Pages 373-377

  Perianayagam, J B ^a   Narayanan, S ^b   Gnanasekar, G ^b   Pandurangan, A ^b   Raja, S ^c   Rajagopal, K ^d   Rajesh, R ^d   Vijayarajkumar, P ^d   Vijayakumar, S G ^d  

^a GURU JAMBHESHWAR UNIVERSITY OF SCIENCE AND TECHNOLOGY   (India)

^b KP College of Pharmacy   (India)

^c JADAVPUR UNIVERSITY   (India)

^d Sanjivani College of Pharmaceutical Sciences   (India)

Author keywords

Antidiarrheal; Emblica officinalis; Euphorbiaceae; Gastrointestinal motility; Intestinal secretion

Indexed keywords

ANTIDIARRHEAL AGENT; CASTOR OIL; CHARCOAL; EMBLICA OFFICINALIS EXTRACT; MAGNESIUM SULFATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIARRHEA; DRUG EFFECT; DRUG EFFICACY; DRUG SCREENING; EUPHORBIA; EXPERIMENTAL MODEL; GASTROINTESTINAL MOTILITY; INTESTINE SECRETION; NONHUMAN; RAT; TRADITIONAL MEDICINE;

ANIMALIA; EUPHORBIACEAE; PHYLLANTHUS EMBLICA;

EID: 22644446005     PISSN: 13880209     EISSN: None     Source Type: Journal    
DOI: 10.1080/13880200590951856     Document Type: Article

References (29)

1. Ahmad J, Mehmood Z, Mohammad F (1998): Screening of some Indian medicinal plants for their antimicrobial properties. J Ethnopharmacol 62: 183-193.
2. Ammon HV, Thomas PJ, Phillips S (1974): Effect of oleic and recinoleic acid on net jejunal water and electrolyte movement. J Clin Invest 53: 374-379.
3. Awouters F, Nimegeers CJE, Lenaerts FM, Janssen PAJ (1978): Delay of castor oil diarrhoea in rats; a new way to evaluate inhibitors of prostaglandin biosynthesis. J Pharm Pharmacol 30: 41-45.
4. Beubler E, Juan H (1979): Effect of ricinoleic acid and other laxatives on net water flux and prostaglandin E release by the rat colon. J Pharm Pharmacol 31: 681-685.
5. Bhattacharya A, Chatterjee A, Ghosal S, Bhattacharya SK (1999): Antioxidant activity of active tannoid principles of Emblica officinalis (Amla). Indian J Exp Biol 37: 676-680.
6. Dajani EZ, Roge EAN, Bertermann RE (1975): Effects of E prostaglandins, disphenoxylate and morphine on intestinal motility in vivo. Eur J Pharm 34: 105-113.
7. Damodaran M, Nair KR (1936): A tannin from the Indian gooseberry (Phyllanthus emblica) with a protective action on ascorbic acid. Biochem J 30: 1014-1020.
8. Doherty SN (1981): Inhibition of arachidonic acid release as the mechanism by which glucocorticoids inhibit endotoxin-induced diarrhoeal. Br J Pharmacol 73: 549-554.
9. Eakins KE, Sanner JH (1972): Prostaglandin antagonists. In: Karim SMM, ed., Prostaglandins Progress in Research. New York: Wiley-Interscience, pp. 263-264.
10. Gaginella TS, Stewart JJ, Olson WA, Bass P (1975): Action of recinoleic acid and structurally related fatty acid on the gastrointestinal tract II. Effect on water a electrolyte absorption in vitro. J Pharm Exp Ther 195: 355-361.
11. Ghosal S, Tripathi VK, Chouhan S (1996): Active constituents of Emblica officinalis: Part I. The chemistry and antioxidant effect of two new hydrolysable tannins, emblicanin A and B. Indian J Chem 35B: 941-948.
12. Gnansekar N, Perianayagam JB (2004): Influence of sodium curcuminate on castor oil-induced diarrhoea in rats. Indian J Pharmacol 36: 177-178.
13. Gunakunru A, Padmanaban K, Thirumal P, Pritila J, Parimala G, Vengatesan N, Gnanasekar N, Perianayagam JB, Sharma SK, Pillai KK (2005): Antidiarrhoeal activity of Butea monosperma in experimental animals. J Ethnopharmacol 98: 241-244.
14. Jeena KJ, Joy KL, Kuttan R (1999): Effect of Emblica officinalis, Phyllanthus amarus and Picrorhizia kurroa on N-nitrosodiethyl amine induced hepatocarcinogenesis. Cancer Lett 136: 11-16.
15. Jose JK, Kuttan Y, Kuttan R (2001): Antitumour activity of Emblica officinalis. J Ethnopharmacol 75: 65-69.
16. Luderer JR, Dermers LN, Hayn AT (1980): Advances in Prostaglandin and Thromboxane Research. New York: Raven Press, pp. 1633-1638.
17. Melo L, Thomas G, Mukherjee R (1988): Antidiarrhoeal activity of bisnordihydro toxiferine isolated from root bark of Strychnos trinervis (Veil.) Mart. (Longaniaceae). J Pharm Pharmacol 40: 79-82.
18. Mukherjee PK, Saha K, Murugesan T, Mandal SC, Pal M, Saha BP (1998): Screening of anti-diarrhoeal profile of some plant extracts of a specific region of West Bengal, India. J Ethnopharmacol 60: 85-89.
19. Parrotta AJ (2001): Healing Plants of Peninsular India. New York: CABI Publishing, pp. 308.
20. Perianayagam JB, Sharma SK, Joseph A, Christiana AJM (2004): Evaluation of antipyretic and analgesic activity of Emblica officinalis Gaertn. J Ethnopharmacol 95: 83-85.
21. Pillay PP, Mahadeva Iyer K (1958): A chemical examination of Emblica officinalis Gaertn. Curent Sci 7: 266-267.
22. Rani S, Ahamed N, Rajaram S, Saluja R, Thenmozhi S, Murugesan T (1999): Antidiarrhoeal evaluation of Clerodendrum phlomidis Linn, leaf extract in rats. J Ethnopharmacol 68: 315-319.
23. Rao MRR, Siddiqui HH (1964): Pharmacological studies on Emblica officinalis Gaertn. Indian J Exp Biol 2: 29-31.
24. Rege NN, Thatte UM, Dahanukar SA (1999): Adaptogenic properties of six Rasayana herbs used in Ayurvedic medicine. Phytother Res 13: 275-291.
25. Sairam K, Rao ChV, Dora Babu M, Vijay Kumar K, Agrawal VK, Goel RK (2002): Antiulcerogenic effect of methanolic extract of Emblica officinalis: An experimental study. J Ethnopharmacol 82: 1-9.
26. Sairam K, Hemalatha S, Kumar A, Srinivasan T, Ganesh J, Shankar M, Venkataraman S (2003): Evaluation of antidiarrhoeal activity in seed extracts of Mangifera indica. J Ethnopharmacol 84: 11-15.
27. Sharma SK, Perianayagam BJ, Joseph A, Christina AJM (2003): Antiinflammatory activity of ethanol and aqueous extracts of Emblica officinalis Gaertn fruits. Hamdard Medicus 46: 75-78.
28. Theresa YM (1968): Studies on Amla [Phyllanthus (emblica) tannins] Part-I isolation of trigalloyl glucose, terehebin, corilogen and ellagic acid from amla fruits. Health Science 15: 337-341.
29. Tripathi KD (1994): Essentials of Medical Pharmacology. New Delhi: Jaypee Brothers Medical Publishers (P), pp. 775.