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Volumn 11, Issue 25, 2005, Pages 3944-3947

5-fluorouracil concentration in blood, liver and tumor tissues and apoptosis of tumor cells after preoperative oral 5′-deoxy-5-fluorouridine in patients with hepatocellular carcinoma

Author keywords

5 fluorouracail; 5 deoxy 5 fluorouridine; Apoptosis; Hepatocellular carcinoma

Indexed keywords

DOXIFLURIDINE; FLUOROURACIL;

EID: 22644441302     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v11.i25.3944     Document Type: Article
Times cited : (9)

References (30)
  • 2
    • 0036841697 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: An epidemiologic view
    • El-Serag HB. Hepatocellular carcinoma: an epidemiologic view. J Clin Gastroenterol 2002; 35(5 Suppl 2): S72-78
    • (2002) J. Clin. Gastroenterol. , vol.35 , Issue.5 SUPPL. 2
    • El-Serag, H.B.1
  • 3
    • 0032849442 scopus 로고    scopus 로고
    • Pyrimidine nucleoside phosphorylase and dihydropyrimidine dehydrogenase indicate chemosensitivity of human colon cancer specimens to doxifluridine and 5-fluorouracil, respectively
    • Kobayashi N, Kubota T, Watanabe M, Otani Y, Teramoto T, Kitajima M. Pyrimidine nucleoside phosphorylase and dihydropyrimidine dehydrogenase indicate chemosensitivity of human colon cancer specimens to doxifluridine and 5-fluorouracil, respectively. J Infect Chemother 1999; 5: 144-148
    • (1999) J. Infect. Chemother. , vol.5 , pp. 144-148
    • Kobayashi, N.1    Kubota, T.2    Watanabe, M.3    Otani, Y.4    Teramoto, T.5    Kitajima, M.6
  • 4
    • 0035068874 scopus 로고    scopus 로고
    • Clinical relevance of the concentrations of both pyrimidine nucleoside phosphorylase (PyNPase) and dihydropyrimidine dehydrogenase (DPD) in colorectal cancer
    • Hiroyasu S, Shiraishi M, Samura H, Tokashiki H, Shimoji H, Isa T, Muto Y. Clinical relevance of the concentrations of both pyrimidine nucleoside phosphorylase (PyNPase) and dihydropyrimidine dehydrogenase (DPD) in colorectal cancer. Jpn J Clin Oncol 2001; 31: 65-68
    • (2001) Jpn. J. Clin. Oncol. , vol.31 , pp. 65-68
    • Hiroyasu, S.1    Shiraishi, M.2    Samura, H.3    Tokashiki, H.4    Shimoji, H.5    Isa, T.6    Muto, Y.7
  • 5
    • 1342331354 scopus 로고    scopus 로고
    • Appropriate duration of postoperative oral adjuvant chemotherapy with HCFU for colorectal cancer
    • Ito K, Okushiba S, Morikawa T, Kondo S, Katoh H. Appropriate duration of postoperative oral adjuvant chemotherapy with HCFU for colorectal cancer. Gan To Kagaku Ryoho 2004; 31: 55-59
    • (2004) Gan To Kagaku Ryoho , vol.31 , pp. 55-59
    • Ito, K.1    Okushiba, S.2    Morikawa, T.3    Kondo, S.4    Katoh, H.5
  • 6
    • 0033776563 scopus 로고    scopus 로고
    • A prospective randomized trial comparing intravenous 5-fluorouracil and oral doxifluridine as postoperative adjuvant treatment for advanced rectal cancer
    • Min JS, Kim NK, Park JK, Yun SH, Noh JK. A prospective randomized trial comparing intravenous 5-fluorouracil and oral doxifluridine as postoperative adjuvant treatment for advanced rectal cancer. Ann Surg Oncol 2000; 7: 674-679
    • (2000) Ann. Surg. Oncol. , vol.7 , pp. 674-679
    • Min, J.S.1    Kim, N.K.2    Park, J.K.3    Yun, S.H.4    Noh, J.K.5
  • 8
    • 0036636784 scopus 로고    scopus 로고
    • Postoperative adjuvant chemotherapy is effective in gastric cancer with serosal invasion: Significance in patients chosen for multivariate analysis
    • Takiguchi N, Fujimoto S, Koda K, Oda K, Okui K, Nakajima N, Miyazaki M. Postoperative adjuvant chemotherapy is effective in gastric cancer with serosal invasion: significance in patients chosen for multivariate analysis. Oncol Rep 2002; 9: 801-806
    • (2002) Oncol. Rep. , vol.9 , pp. 801-806
    • Takiguchi, N.1    Fujimoto, S.2    Koda, K.3    Oda, K.4    Okui, K.5    Nakajima, N.6    Miyazaki, M.7
  • 9
    • 0346103805 scopus 로고    scopus 로고
    • Capecitabine inhibits postoperative recurrence and metastasis after liver cancer resection in nude mice with relation to the expression of platelet-derived endothelial cell growth factor
    • Zhou J, Tang ZY, Fan J, Wu ZQ, Ji Y, Xiao YS, Shi YH, Li XM, Sun QM, Liu YK, Ye SL. Capecitabine inhibits postoperative recurrence and metastasis after liver cancer resection in nude mice with relation to the expression of platelet-derived endothelial cell growth factor. Clin Cancer Res 2003; 9(16 Pt 1): 6030-6037
    • (2003) Clin. Cancer Res. , vol.9 , Issue.16 PART 1 , pp. 6030-6037
    • Zhou, J.1    Tang, Z.Y.2    Fan, J.3    Wu, Z.Q.4    Ji, Y.5    Xiao, Y.S.6    Shi, Y.H.7    Li, X.M.8    Sun, Q.M.9    Liu, Y.K.10    Ye, S.L.11
  • 10
    • 0033654285 scopus 로고    scopus 로고
    • Intratumoral pyrimidine nucleoside phosphorylase (PyNPase) activity predicts a selective effect of adjuvant 5′-deoxy-5-fluorouridine (5′DFUR) on breast cancer
    • Hata Y, Takahashi H, Sasaki F, Ogita, M, Uchino J, Yoshimoto M, Akasaka Y, Nakanishi Y, Sawada Y. Intratumoral pyrimidine nucleoside phosphorylase (PyNPase) activity predicts a selective effect of adjuvant 5′-deoxy-5-fluorouridine (5′DFUR) on breast cancer. Breast Cancer 2000; 7: 37-41
    • (2000) Breast Cancer , vol.7 , pp. 37-41
    • Hata, Y.1    Takahashi, H.2    Sasaki, F.3    Ogita, M.4    Uchino, J.5    Yoshimoto, M.6    Akasaka, Y.7    Nakanishi, Y.8    Sawada, Y.9
  • 12
    • 0037382224 scopus 로고    scopus 로고
    • Determination of 5-fluorouracil and its prodrug tegafur in plasma and tissue by high-performance liquid chromatography in a single injection: Validation for application in clinical pharmacokinetic studies
    • Zufia L, Aldaz A, Castellanos C, Giraldez J. Determination of 5-fluorouracil and its prodrug tegafur in plasma and tissue by high-performance liquid chromatography in a single injection: validation for application in clinical pharmacokinetic studies. Ther Drug Monit 2003; 23: 221-228
    • (2003) Ther. Drug Monit. , vol.23 , pp. 221-228
    • Zufia, L.1    Aldaz, A.2    Castellanos, C.3    Giraldez, J.4
  • 15
    • 1642525639 scopus 로고    scopus 로고
    • Beta-hydroxyisovalerylshikonin and cisplatin act synergistically to inhibit growth and to induce apoptosis of human lung cancer DMS114 cells via a tyrosine kinase-dependent pathway
    • Xu Y, Kajimoto S, Nakajo S, Nakaya K. Beta-hydroxyisovalerylshikonin and cisplatin act synergistically to inhibit growth and to induce apoptosis of human lung cancer DMS114 cells via a tyrosine kinase-dependent pathway. Oncology 2004; 66: 67-75
    • (2004) Oncology , vol.66 , pp. 67-75
    • Xu, Y.1    Kajimoto, S.2    Nakajo, S.3    Nakaya, K.4
  • 16
    • 0036389582 scopus 로고    scopus 로고
    • Vitamin E succinate inhibits colon cancer liver metastases
    • Barnett KT, Fokum FD, Malafa MP. Vitamin E succinate inhibits colon cancer liver metastases. J Surg Res 2002; 106: 292-298
    • (2002) J. Surg. Res. , vol.106 , pp. 292-298
    • Barnett, K.T.1    Fokum, F.D.2    Malafa, M.P.3
  • 17
    • 0036789367 scopus 로고    scopus 로고
    • Reversal of drug resistance of hepatocellular carcinoma cells by adenoviral delivery of anti-MDR1 ribozymes
    • Huesker M, Folmer Y, Schneider M, Fulda C, Blum HE, Hafkemeyer P. Reversal of drug resistance of hepatocellular carcinoma cells by adenoviral delivery of anti-MDR1 ribozymes. Hepatology 2002; 36(4 Pt 1): 874-884
    • (2002) Hepatology , vol.36 , Issue.4 PART 1 , pp. 874-884
    • Huesker, M.1    Folmer, Y.2    Schneider, M.3    Fulda, C.4    Blum, H.E.5    Hafkemeyer, P.6
  • 18
    • 0842311702 scopus 로고    scopus 로고
    • P-glycoprotein modulation improves in vitro chemosensitivity in malignant pediatric liver tumors
    • Warmann S, Gohring G, Teichmann B, Geerlings H, Pietsch T, Fuchs J. P-glycoprotein modulation improves in vitro chemosensitivity in malignant pediatric liver tumors. Anticancer Res 2003; 23: 4607-4611
    • (2003) Anticancer Res. , vol.23 , pp. 4607-4611
    • Warmann, S.1    Gohring, G.2    Teichmann, B.3    Geerlings, H.4    Pietsch, T.5    Fuchs, J.6
  • 19
    • 0034177143 scopus 로고    scopus 로고
    • Limited but definite efficacy of prophylactic hepatic arterial infusion chemotherapy after curative resection of colorectal liver metastases: A randomized study
    • Tono T, Hasuike Y, Ohzato H, Takatsuka Y, Kikkawa N. Limited but definite efficacy of prophylactic hepatic arterial infusion chemotherapy after curative resection of colorectal liver metastases: A randomized study. Cancer 2000; 88: 1549-1556
    • (2000) Cancer , vol.88 , pp. 1549-1556
    • Tono, T.1    Hasuike, Y.2    Ohzato, H.3    Takatsuka, Y.4    Kikkawa, N.5
  • 20
    • 0033724392 scopus 로고    scopus 로고
    • Evaluation of combined therapy with chemoembolization and irradiation for large hepatocellular carcinoma
    • Guo WJ, Yu EX. Evaluation of combined therapy with chemoembolization and irradiation for large hepatocellular carcinoma. Br J Radiol 2000; 73: 1091-1097
    • (2000) Br. J. Radiol. , vol.73 , pp. 1091-1097
    • Guo, W.J.1    Yu, E.X.2
  • 21
    • 0036207299 scopus 로고    scopus 로고
    • Overexpression of pyrimidine nucleoside phosphorylase enhances the sensitivity to 5′-deoxy-5-fluorouridine in tumour cells in vitro and in vivo
    • Nagata T, Nakamori M, Iwahashi M, Yamaue H. Overexpression of pyrimidine nucleoside phosphorylase enhances the sensitivity to 5′-deoxy-5-fluorouridine in tumour cells in vitro and in vivo. Eur J Cancer 2002; 38: 712-717
    • (2002) Eur. J. Cancer , vol.38 , pp. 712-717
    • Nagata, T.1    Nakamori, M.2    Iwahashi, M.3    Yamaue, H.4
  • 22
    • 0032797555 scopus 로고    scopus 로고
    • Increased cytotoxicity and bystander effect of 5-fluorouracil and 5-deoxy-5-fluorouridine in human colorectal cancer cells transfected with thymidine phosphorylase
    • Evrard A, Cuq P, Ciccolini J, Vian L, Cano JP. Increased cytotoxicity and bystander effect of 5-fluorouracil and 5-deoxy-5-fluorouridine in human colorectal cancer cells transfected with thymidine phosphorylase. Br J Cancer 1999; 80: 1726-1733
    • (1999) Br. J. Cancer , vol.80 , pp. 1726-1733
    • Evrard, A.1    Cuq, P.2    Ciccolini, J.3    Vian, L.4    Cano, J.P.5
  • 24
    • 0344267645 scopus 로고    scopus 로고
    • Enhancement of 5-fluorouracil cytotoxicity by human thymidine-phosphorylase expression in cancer cells: In vitro and in vivo study
    • Evrard P, Cuq P, Robert B, Vian L, Pelegrin A, Cano JP. Enhancement of 5-fluorouracil cytotoxicity by human thymidine-phosphorylase expression in cancer cells: in vitro and in vivo study. Int J Cancer 1999; 80: 465-470
    • (1999) Int. J. Cancer , vol.80 , pp. 465-470
    • Evrard, P.1    Cuq, P.2    Robert, B.3    Vian, L.4    Pelegrin, A.5    Cano, J.P.6
  • 25
    • 0033776563 scopus 로고    scopus 로고
    • A prospective randomized trial comparing intravenous 5-fluorouracil and oral doxifluridine as postoperative adjuvant treatment for advanced rectal cancer
    • Min JS, Kim NK, Park JK, Yun SH, Noh JK. A prospective randomized trial comparing intravenous 5-fluorouracil and oral doxifluridine as postoperative adjuvant treatment for advanced rectal cancer. Ann Surg Oncol 2000; 7: 674-679
    • (2000) Ann. Surg. Oncol. , vol.7 , pp. 674-679
    • Min, J.S.1    Kim, N.K.2    Park, J.K.3    Yun, S.H.4    Noh, J.K.5
  • 26
    • 0032905932 scopus 로고    scopus 로고
    • Expression of pyrimidine nucleoside phosphorylase mRNA plays an important role in the prognosis of patients with oesophageal cancer
    • Yamagata M, Mori M, Mimori K, Mafune KI, Tanaka Y, Ueo Y, Akiyoshi T. Expression of pyrimidine nucleoside phosphorylase mRNA plays an important role in the prognosis of patients with oesophageal cancer. Br J Cancer 1999; 79: 565-569
    • (1999) Br. J. Cancer , vol.79 , pp. 565-569
    • Yamagata, M.1    Mori, M.2    Mimori, K.3    Mafune, K.I.4    Tanaka, Y.5    Ueo, Y.6    Akiyoshi, T.7
  • 27
    • 0033061591 scopus 로고    scopus 로고
    • Up-regulated pyrimidine nucleoside phosphorylase in breast carcinoma correlates with lymph node metastasis
    • Mimori K, Ueo H, Shirasaka C, Shiraishi T, Yamagata M, Haraguchi M, Mori M. Up-regulated pyrimidine nucleoside phosphorylase in breast carcinoma correlates with lymph node metastasis. Ann Oncol 1999; 10: 111-113
    • (1999) Ann. Oncol. , vol.10 , pp. 111-113
    • Mimori, K.1    Ueo, H.2    Shirasaka, C.3    Shiraishi, T.4    Yamagata, M.5    Haraguchi, M.6    Mori, M.7
  • 28
    • 0141816776 scopus 로고    scopus 로고
    • PyNPase and DPD expression potentially predict response to 5′-DFUR treatment for node-positive breast cancer patients
    • Akao S, Inoue K. PyNPase and DPD expression potentially predict response to 5′-DFUR treatment for node-positive breast cancer patients. Gan To Kagaku Ryoho 2003; 30: 1361-1364
    • (2003) Gan To Kagaku Ryoho , vol.30 , pp. 1361-1364
    • Akao, S.1    Inoue, K.2
  • 29
    • 0030900291 scopus 로고    scopus 로고
    • Inhibitory effects of fluorinated pyrimidines, 5′-DFUR, UFT and T-506, in a model of hepatic metastasis of mouse colon 26 adenocarcinoma-assessment of inhibitory activity and adverse reactions at the maximum tolerated dose
    • Tazawa K, Sakamoto T, Kuroki Y, Yamashita I, Okamoto M, Katuyama S, Fujimaki M. Inhibitory effects of fluorinated pyrimidines, 5′-DFUR, UFT and T-506, in a model of hepatic metastasis of mouse colon 26 adenocarcinoma-assessment of inhibitory activity and adverse reactions at the maximum tolerated dose. Clin Exp Metastasis 1997; 15: 266-271
    • (1997) Clin. Exp. Metastasis , vol.15 , pp. 266-271
    • Tazawa, K.1    Sakamoto, T.2    Kuroki, Y.3    Yamashita, I.4    Okamoto, M.5    Katuyama, S.6    Fujimaki, M.7


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