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Volumn 1, Issue 1, 2003, Pages 5-17

Drugs from the sea-opportunities and obstacles

Author keywords

Biotechnology; Drugs from the sea; Endosymbionts; Mariculture

Indexed keywords


EID: 22644432311     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md101005     Document Type: Review
Times cited : (87)

References (32)
  • 1
    • 0034082239 scopus 로고    scopus 로고
    • The influence of natural products upon drug discovery
    • Newman, D. J.; Cragg, G. M.; Snader, K. M. The influence of natural products upon drug discovery. Nat. Prod. Rep. 2000, 17, 215-234.
    • (2000) Nat. Prod. Rep , vol.17 , pp. 215-234
    • Newman, D. J.1    Cragg, G. M.2    Snader, K. M.3
  • 2
    • 0000719402 scopus 로고
    • Contribution to the study of marine sponges. 32. The nucleosides of sponges
    • Bergmann, W.; Feeney, R. Contribution to the study of marine sponges. 32. The nucleosides of sponges. J. Org. Chem. 1951, 16, 981-987.
    • (1951) J. Org. Chem , vol.16 , pp. 981-987
    • Bergmann, W.1    Feeney, R.2
  • 4
    • 0032862623 scopus 로고    scopus 로고
    • Marine natural products as therapeutic agents
    • Kerr, R. G.; Kerr, S. S. Marine natural products as therapeutic agents. Expert Opin. Ther. Pat. 1999, 9, 1207-1222.
    • (1999) Expert Opin. Ther. Pat , vol.9 , pp. 1207-1222
    • Kerr, R. G.1    Kerr, S. S.2
  • 5
    • 0036314931 scopus 로고    scopus 로고
    • Drugs from the Seas – Current Status and Microbiological Implications
    • Proksch, P.; Edrada, R. A.; Ebel, R. Drugs from the Seas – Current Status and Microbiological Implications. Appl. Microbiol. Biotech. 2002, 59, 125-134.
    • (2002) Appl. Microbiol. Biotech , vol.59 , pp. 125-134
    • Proksch, P.1    Edrada, R. A.2    Ebel, R.3
  • 6
    • 0021261895 scopus 로고
    • Antiviral agents from a gorgonian Eunicella cavolini; one previously found in the sponge Cryptotehya crypta
    • Cimino, G.; De Rosa S.; De Stefano S. Antiviral agents from a gorgonian Eunicella cavolini; one previously found in the sponge Cryptotehya crypta. Experientia 1984, 40, 339-340.
    • (1984) Experientia , vol.40 , pp. 339-340
    • Cimino, G.1    De Rosa, S.2    De Stefano, S.3
  • 7
    • 0002829177 scopus 로고    scopus 로고
    • Aquacultural production of bryostatin 1 and ecteinascidin 743
    • Fusetani, N., Ed.; Karger: Basel
    • Mendola, D. Aquacultural production of bryostatin 1 and ecteinascidin 743. In Drugs from the sea; Fusetani, N., Ed.; Karger: Basel, 2000, pp 120-133.
    • (2000) Drugs from the sea , pp. 120-133
    • Mendola, D.1
  • 8
  • 9
    • 0002224261 scopus 로고    scopus 로고
    • ω-conotoxin MVIIA: From marine snail venom to analgesic drug
    • Fusetani, N., Ed.; Karger: Basel
    • Olivera, B. M. ω-conotoxin MVIIA: From marine snail venom to analgesic drug. In Drugs from the sea; Fusetani, N., Ed.; Karger: Basel, 2000; pp 74–85.
    • (2000) Drugs from the sea , pp. 74-85
    • Olivera, B. M.1
  • 10
    • 0033868507 scopus 로고    scopus 로고
    • Chemistry and clinical biology of the bryostatins
    • Mutter, R.; Wills, M. Chemistry and clinical biology of the bryostatins. Bioorg. Med. Chem. 2000, 8, 1841-1860.
    • (2000) Bioorg. Med. Chem , vol.8 , pp. 1841-1860
    • Mutter, R.1    Wills, M.2
  • 11
    • 0028244823 scopus 로고
    • Jasplakinolide, a cytotoxic natural product, induces actin polymerization and competitively inhibits the binding of phalloidin to F-actin
    • Bubb, M. R.; Senderowicz, A. M.; Sausville, E. A.; Duncan, K. L.; Korn, E. D. Jasplakinolide, a cytotoxic natural product, induces actin polymerization and competitively inhibits the binding of phalloidin to F-actin. J. Biol. Chem. 1994, 269, 14869-14871.
    • (1994) J. Biol. Chem , vol.269 , pp. 14869-14871
    • Bubb, M. R.1    Senderowicz, A. M.2    Sausville, E. A.3    Duncan, K. L.4    Korn, E. D.5
  • 12
    • 33748883210 scopus 로고    scopus 로고
    • Chondramides A – D, new cytostatic and antifungal cyclodepsipeptides from Chondromyces crocatus (Myxobacteria): Isolation and structure elucidation
    • Jansen, R.; Kunze, B.; Reichenbach; H.; Höfle, G. Chondramides A – D, new cytostatic and antifungal cyclodepsipeptides from Chondromyces crocatus (Myxobacteria): Isolation and structure elucidation. Liebigs Ann. 1996, 2, 285-290.
    • (1996) Liebigs Ann , vol.2 , pp. 285-290
    • Jansen, R.1    Kunze, B.2    Reichenbach, H.3    Höfle, G.4
  • 13
    • 0020836368 scopus 로고
    • Safracins, new antitumor antibiotics. II. Physicochemical properties and chemical structures
    • Ikeda, Y.; Matsuki, H.; Ogawa, T.; Munakata, T. Safracins, new antitumor antibiotics. II. Physicochemical properties and chemical structures. J. Antibiot. 1983, 36, 1284-1289.
    • (1983) J. Antibiot , vol.36 , pp. 1284-1289
    • Ikeda, Y.1    Matsuki, H.2    Ogawa, T.3    Munakata, T.4
  • 16
    • 0034898713 scopus 로고    scopus 로고
    • Isolation of dolastatin 10 from the marine cyanobacterium Symploca species VP642 and total stereochemistry and biological evaluation of its analogue symplostatin 1
    • Luesch, H.; Moore, R. E.; Paul, V. J.; Mooberry, S. L.; Corbett, T. H. Isolation of dolastatin 10 from the marine cyanobacterium Symploca species VP642 and total stereochemistry and biological evaluation of its analogue symplostatin 1. J. Nat. Prod. 2001, 64, 907-910.
    • (2001) J. Nat. Prod , vol.64 , pp. 907-910
    • Luesch, H.1    Moore, R. E.2    Paul, V. J.3    Mooberry, S. L.4    Corbett, T. H.5
  • 17
    • 0036383653 scopus 로고    scopus 로고
    • The cyanobacterial origin of potent anticancer agents originally isolated from sea hares
    • Luesch, H.; Harrigan, G. G.; Goetz, G.; Horgen, F. D. The cyanobacterial origin of potent anticancer agents originally isolated from sea hares. Curr. Med. Chem. 2002, 9, 1791-1806.
    • (2002) Curr. Med. Chem , vol.9 , pp. 1791-1806
    • Luesch, H.1    Harrigan, G. G.2    Goetz, G.3    Horgen, F. D.4
  • 18
    • 0032811757 scopus 로고    scopus 로고
    • Staurosporine derivatives from the ascidican Eudistoma toealensis and its predatory flatworm Pseudoceros sp
    • Schupp, P.; Wray, V.; Eder, C.; Schneider, P.; Herderich, M.; Paul, V.; Proksch, P. Staurosporine derivatives from the ascidican Eudistoma toealensis and its predatory flatworm Pseudoceros sp. J. Nat. Prod. 1999, 62, 959-962.
    • (1999) J. Nat. Prod , vol.62 , pp. 959-962
    • Schupp, P.1    Wray, V.2    Eder, C.3    Schneider, P.4    Herderich, M.5    Paul, V.6    Proksch, P.7
  • 19
    • 85008014440 scopus 로고
    • Identification of okadaic acid as a toxic component of a marine dinoflagellate Prorocentrum lima
    • Murakami, Y.; Oshima, Y.; Yasumoto, T. Identification of okadaic acid as a toxic component of a marine dinoflagellate Prorocentrum lima. Bull. Jp. Soc. Fish Sci. 1982, 48, 69-72.
    • (1982) Bull. Jp. Soc. Fish Sci , vol.48 , pp. 69-72
    • Murakami, Y.1    Oshima, Y.2    Yasumoto, T.3
  • 20
    • 0029794187 scopus 로고    scopus 로고
    • Two classes of metabolites from Theonella swinhoei are localized in distinct populations of bacterial symbionts
    • Bewley, C. A.; Holland, N. D.; Faulkner, D. J. Two classes of metabolites from Theonella swinhoei are localized in distinct populations of bacterial symbionts. Experientia 1996, 52, 716-722.
    • (1996) Experientia , vol.52 , pp. 716-722
    • Bewley, C. A.1    Holland, N. D.2    Faulkner, D. J.3
  • 21
    • 0031678722 scopus 로고    scopus 로고
    • Lithistid sponges: Star performers or hosts to the stars?
    • Bewley, C. A.; Faulkner, D. J. Lithistid sponges: Star performers or hosts to the stars? Angew. Chem. Int. Ed. 1998, 37, 2162-2178.
    • (1998) Angew. Chem. Int. Ed , vol.37 , pp. 2162-2178
    • Bewley, C. A.1    Faulkner, D. J.2
  • 22
    • 0000693758 scopus 로고    scopus 로고
    • Identification of the antifungal peptide-containing symbiont of the marine sponge Theonella swinhoei as a novel δproteobacterium, “Candidatus Entotheonella palauensis
    • Schmidt, E. W.; Obraztsova, A. Y.; Davidson, S. K.; Faulkner, D. J.; Haygood, M. G. Identification of the antifungal peptide-containing symbiont of the marine sponge Theonella swinhoei as a novel δproteobacterium, “Candidatus Entotheonella palauensis”. Mar. Biol. 2000, 136, 969-977.
    • (2000) Mar. Biol , vol.136 , pp. 969-977
    • Schmidt, E. W.1    Obraztsova, A. Y.2    Davidson, S. K.3    Faulkner, D. J.4    Haygood, M. G.5
  • 23
    • 0027300730 scopus 로고
    • Cyanobacterial symbiont biosynthesis of chlorinated metabolites from Dysidea herbacea (Porifera)
    • Unson, M. D.; Faulkner, D. J. Cyanobacterial symbiont biosynthesis of chlorinated metabolites from Dysidea herbacea (Porifera). Experientia 1993, 49, 349-353.
    • (1993) Experientia , vol.49 , pp. 349-353
    • Unson, M. D.1    Faulkner, D. J.2
  • 24
    • 0031868508 scopus 로고    scopus 로고
    • Cellular origin of chlorinated diketopiperazines in the dictyoceratid sponge Dysidea herbacea (Keller)
    • Flowers, A. E.; Garson, M. J.; Webb, R. I.; Dumdei, E. J.; Charan, R. D. Cellular origin of chlorinated diketopiperazines in the dictyoceratid sponge Dysidea herbacea (Keller). Cell Tissue Res. 1998, 292, 597-607.
    • (1998) Cell Tissue Res , vol.292 , pp. 597-607
    • Flowers, A. E.1    Garson, M. J.2    Webb, R. I.3    Dumdei, E. J.4    Charan, R. D.5
  • 25
    • 85069034851 scopus 로고    scopus 로고
    • Temporal variation of the microbial community associated with the Mediterranean sponge Aplysina aerophoba
    • Friedrich, A. B.; Fischer, I.; Proksch, P.; Hacker, J.; Hentschel, U. Temporal variation of the microbial community associated with the Mediterranean sponge Aplysina aerophoba. FEMS Microbiol. Ecol. 2001, 1301, 1-9.
    • (2001) FEMS Microbiol. Ecol , vol.1301 , pp. 1-9
    • Friedrich, A. B.1    Fischer, I.2    Proksch, P.3    Hacker, J.4    Hentschel, U.5
  • 26
    • 0037195174 scopus 로고    scopus 로고
    • A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles
    • Piel, J. A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles. Proc. Natl. Acad. Sci. USA 2002, 99, 14002-14007.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 14002-14007
    • Piel, J.1
  • 27
    • 0034571687 scopus 로고    scopus 로고
    • The pederin family of antitumor agents: structures, synthesis and biological activity
    • Narquizian, R.; Kocienski, P. J. The pederin family of antitumor agents: structures, synthesis and biological activity. Ernst Schering Res. Found. Workshop 2000, 32, 25-56.
    • (2000) Ernst Schering Res. Found. Workshop , vol.32 , pp. 25-56
    • Narquizian, R.1    Kocienski, P. J.2
  • 28
    • 0023726527 scopus 로고
    • Mycalamide A, an antiviral compound from a New Zealand sponge of genus Mycale
    • Perry, N. B.; Blunt, J. W.; Munro, M. H. G.; Pannell, L. K. Mycalamide A, an antiviral compound from a New Zealand sponge of genus Mycale. J. Am. Chem. Soc. 1988, 110, 4850-4851.
    • (1988) J. Am. Chem. Soc , vol.110 , pp. 4850-4851
    • Perry, N. B.1    Blunt, J. W.2    Munro, M. H. G.3    Pannell, L. K.4
  • 29
    • 0035025064 scopus 로고    scopus 로고
    • Induction of apoptosis by the marine sponge (Mycale) metabolites, mycalamide A and pateamine
    • Hood, K. A.; West, L. M.; Northcote, P. T.; Berridge, M. V.M.; Miller, J. H. Induction of apoptosis by the marine sponge (Mycale) metabolites, mycalamide A and pateamine. Apoptosis 2001, 6, 207219.
    • (2001) Apoptosis , vol.6 , pp. 207219
    • Hood, K. A.1    West, L. M.2    Northcote, P. T.3    Berridge, M. V.M.4    Miller, J. H.5
  • 30
    • 0036009127 scopus 로고    scopus 로고
    • Molecular identification of an endosymbiotic bacterium associated with pederin biosynthesis in Paederus sabaeus (Coleoptera: Staphylinidae)
    • Kellner, R. L. Molecular identification of an endosymbiotic bacterium associated with pederin biosynthesis in Paederus sabaeus (Coleoptera: Staphylinidae). Insect Biochem. Mol. Biol. 2002, 32, 389-395.
    • (2002) Insect Biochem. Mol. Biol , vol.32 , pp. 389-395
    • Kellner, R. L.1
  • 31
    • 4243369786 scopus 로고    scopus 로고
    • Biosynthesis of bioactive marine natural products
    • Atta-ur-Rahman, Ed., Elsevier: Amsterdam
    • Kerr, R. G. Biosynthesis of bioactive marine natural products. In Studies in Natural Products Chemistry Vol 21. Atta-ur-Rahman, Ed., Elsevier: Amsterdam, 2000; pp 293–328.
    • (2000) Studies in Natural Products Chemistry , vol.21 , pp. 293-328
    • Kerr, R. G.1
  • 32
    • 0342542060 scopus 로고    scopus 로고
    • Cyanide and thiocyanate-derived functionality in marine organisms-structures, biosynthesis and ecology
    • Atta-ur-Rahman, Ed., Elsevier: Amsterdam
    • Garson, M. J.; Simpson, J. S.; Flowers, A. E.; Dumdei, E. J. Cyanide and thiocyanate-derived functionality in marine organisms-structures, biosynthesis and ecology. In Studies in Natural Products Chemistry Vol 21. Atta-ur-Rahman, Ed., Elsevier: Amsterdam, 2000; pp. 329-372.
    • (2000) Studies in Natural Products Chemistry , vol.21 , pp. 329-372
    • Garson, M. J.1    Simpson, J. S.2    Flowers, A. E.3    Dumdei, E. J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.