Indole alkaloids and other constituents of Rauwolfia serpentina

Journal of Natural Products

Volumn 68, Issue 6, 2005, Pages 848-852

  Itoh, Atsuko ^a   Kumashiro, Tomoko ^a   Yamaguchi, Machiko ^a   Nagakura, Naotaka ^a   Mizushina, Yoshiyuki ^b   Nishi, Toyoyuki ^c   Tanahashi, Takao ^a  

^a KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

^b KOBE GAKUIN UNIVERSITY   (Japan)

^c Nippon Shinyaku Inst for Bot Res   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

18 HYDROXYEPIYOHIMBINE; 3 HYDROXYSARPAGINE; 6' O (3,4,5 TRIMETHOXYBENZOYL)GLOMERATOSE A; 7 EPILOGANIN; ANTINEOPLASTIC AGENT; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE INHIBITOR; ETOPOSIDE; GYRASE INHIBITOR; INDOLE ALKALOID; ISORAUHIMBINE; ISORAUHIMBINIC ACID; N BETA METHYLAJMALINE; N BETA METHYLISOAJMALINE; RAUWOLFIA EXTRACT; RESERPINE; SUCROSE; UNCLASSIFIED DRUG; YOHIMBINE; YOHIMBINIC ACID;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL STRAIN HL 60; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG SCREENING; ENZYME INHIBITION; HUMAN; HUMAN CELL; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; PHYTOCHEMISTRY; PLANT ROOT; PROTON NUCLEAR MAGNETIC RESONANCE; RAUWOLFIA; STRUCTURE ACTIVITY RELATION; ULTRAVIOLET SPECTROSCOPY;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; DRUG SCREENING ASSAYS, ANTITUMOR; HL-60 CELLS; HUMANS; INDOLE ALKALOIDS; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PLANT ROOTS; PLANTS, MEDICINAL; RAUWOLFIA; THAILAND;

RAUVOLFIA SERPENTINA;

EID: 22544463084     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np058007n     Document Type: Article

References (25)

1. Stöckigt, J. In The Alkaloids, Vol. 47; Cordell, G. A., Ed.; Academic Press: New York, 1995; Chapter 2.
2. Neuss, N. In Indole and Biogenetically Related Alkaloids; Phillipson, J. D.; Zenk, M. H., Eds.; Academic Press: New York, 1980; Chapter 17.
3. Jokela, R.; Lounasmaa, M. Planta Med. 1996, 62, 577-579.
4. Majumdar, S. P.; Poisson, J.; Potier, P. Phytochemistry 1973, 12, 1167-1169.
5. Djerassi, C.; Fishmen, J.; Gorman, M.; Kutney, J. P.; Pakrashi, S. C. J. Am. Chem. Soc. 1957, 79, 1217-1222.
6. Schübel, H.; Treiber, A.; Stöckigt, J. Helv. Chim. Acta 1984, 67, 2078-2081.
7. Clivio, P.; Richard, B.; Deverre, J.-R.; Sevenet, T.; Zeches, M.; Olivier, L. L. Phytochemistry 1991, 30, 3785-3792.
8. Feng, X. Z.; Kan, C.; Potier, P.; Kan, S.-K.; Lounasmaa, M. Planta Med. 1982, 44, 212-214.
9. Atta-Ur-Rahman; Malik, S.; Habit-ur-Rehman. Phytochemistry 1986, 25 1731-1733
10. Wenkert, E.; Chang, C.-J.; Chawla, H. P. S.; Cochran, D. W.; Hagaman, E. W.; King, J. C.; Onto, K. J. Am. Chem. Soc. 1976, 98, 3645-3655.
11. Nakamoto, K.; Otsuka, H.; Yamasaki, K. Phytochemistry 1988, 27, 1856-1858.
12. Muhammad, I.; Dunbar, D. C.; Khan, R. A.; Ganzera, M.; Khan, I. A. Phytochemistry 2001, 57, 781-785.
13. Calis, I.; Sticher, O. Phytochemistry 1984, 23, 2539-2540.
14. Achenbach, H.; Löwel, M.; Waigbel, R.; Gupta, M.; Sous, P. Planta Med. 1992, 58, 270-272.
15. Zhang, D.; Miyase, T.; Kuroyamagi, M.; Umehara, K.; Noguchi, H. Phytochemistry 1998, 47, 45-52.
16. Levin, R. H.; Lallemand, J.-Y.; Roberts, J. D. J. Org. Chem. 1973, 38, 1983-1986.
17. Batiste, C. V. F.; Schripsema, J.; Verpoorte, R.; Rech, S. B.; Henriques, A. T. Phytochemistry 1996, 41, 969-973.
18. Danieli, B.; Lesma, G.; Palmisano, G.; Ricca, G. S. Tetrahedron 1984, 40, 5255-5261.
19. Stoll, A.; Hofmann, A. Helv. Chim. Acta 1953, 36, 1143-1147.
20. Hofmann, A. Helv. Chim. Acta 1954, 37, 849-865.
21. Ikeshiro, Y.; Tomita, Y. Planta Med. 1984, 50, 485-488.
22. Hara, S.; Okabe, H.; Mihashi, K. Chem. Pharm. Bull. 1986, 34, 1843-1845.
23. Mizushina, Y.; Akihisa, T.; Ukiya, M.; Murakami, C.; Kuriyama, I.; Xu, X.; Yoshida, H.; Sakaguchi, K. Cancer Sci. 2004, 95, 354-360.
24. Spitzner, J. R.; Chung, I. K.; Muller, M. T. Nucleic Acids Res. 1990, 18, 1-11.
25. Mosmann, T. J. Immunol. Methods 1983, 65, 55-63.