cAMP-response element-binding protein and heat-shock protein 70 additively suppress polyglutamine-mediated toxicity in Drosophila

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 29, 2005, Pages 10261-10266

  Iijima Ando, Kanae ^a   Wu, Priscilla ^a   Drier, Eric A ^a,b   Iijima, Koichi ^a   Yin, Jerry C P ^a,b  

^a Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Molecular chaperones; PKA; Polyglutamine diseases; Transcription

Indexed keywords

CHAPERONE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; HEAT SHOCK PROTEIN 70; POLYGLUTAMINE;

ANIMAL MODEL; ARTICLE; CAG REPEAT; DCREB2 GENE; DEGENERATIVE DISEASE; DROSOPHILA; GENE; GENE DOSAGE; GENE MUTATION; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HUNTINGTON CHOREA; LETHALITY; NERVOUS SYSTEM; NONHUMAN; NUCLEOTIDE REPEAT; POLYGLUTAMINE DISEASE; PRIORITY JOURNAL; PROTECTION; REPORTER GENE; TOXICITY;

ANIMALS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DROSOPHILA; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION; HSP70 HEAT-SHOCK PROTEINS; LUCIFERASES; NERVOUS SYSTEM DISEASES; NEURONS; PEPTIDES; SURVIVAL ANALYSIS; TRANS-ACTIVATORS; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 22544457461     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0503937102     Document Type: Article

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