Timolol/dorzolamide combination therapy as initial treatment for intraocular pressure over 30 mm Hg

Journal of Glaucoma

Volumn 14, Issue 4, 2005, Pages 267-270

  Henderer, Jeffrey D ^a   Wilson, Richard P ^a   Moster, Marlene R ^a   Myers, Jonathan ^a   Schmidt, Courtland ^a   Fontanarosa, Joann ^a   Steinmann, William C ^a,b  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cosopt; Dorzolamide; IOP reduction; Timolol

Indexed keywords

DORZOLAMIDE PLUS TIMOLOL;

ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG RESPONSE; EYE BURNING; EYE PAIN; FOREIGN BODY; FOREIGN BODY SENSATION; HEADACHE; HUMAN; INTRAOCULAR HYPERTENSION; INTRAOCULAR PRESSURE; OPEN ANGLE GLAUCOMA; PATIENT MONITORING; PIGMENT GLAUCOMA; PRESSURE MEASUREMENT; PRIORITY JOURNAL; SECONDARY GLAUCOMA; STINGING;

ADULT; ANTIHYPERTENSIVE AGENTS; CIRCADIAN RHYTHM; DRUG COMBINATIONS; DRUG THERAPY, COMBINATION; GLAUCOMA, OPEN-ANGLE; HUMANS; INTRAOCULAR PRESSURE; PROSPECTIVE STUDIES; SULFONAMIDES; THIOPHENES; TIMOLOL; TONOMETRY, OCULAR;

EID: 22544455038     PISSN: 10570829     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ijg.0000169389.09804.33     Document Type: Article

References (17)

1. Collaborative Normal-Tension Glaucoma Study Group. Comparison of glaucomatous progression between untreated patients with normal-tension glaucoma and patients with therapeutically reduced intraocular pressures. Am J Ophthalmol. 1998;126:487-497.
2. Collaborative Normal-Tension Glaucoma Study Group. The effectiveness of intraocular pressure reduction in the treatment of normal-tension glaucoma. Am J Ophthalmol. 1998;126:498-505.
3. The Advanced Glaucoma Intervention Study (AGIS). 7. The relationship between control of intraocular pressure and visual field deterioration. The AGIS Investigators. Am J Ophthalmol. 2000;130:429-440.
4. The Glaucoma Laser Trial (GLT) and glaucoma laser trial follow-up study: 7. Results. Glaucoma Laser Trial Research Group. Am J Ophthalmol. 1995;120:718-731.
5. Heijl A, Leske MC, Bengtsson B, et al. Reduction of intraocular pressure and glaucoma progression: results from the Early Manifest Glaucoma Trial. Arch Ophthalmol. 2002;120:1268-1279.
6. Camras CB, Alm A, Watson P, et al. Latanoprost, a prostaglandin analog, for glaucoma therapy. Efficacy and safety after 1 year of treatment in 198 patients. Latanoprost Study Groups. Ophthalmology. 1996;103:1916-1924.
7. Garcia-Sanchez J. Efficacy and side effects of latanoprost monotherapy compared to adding dorzolamide to timolol in patients with glaucoma and ocular hypertension - a three-month randomised study. Spanish Latanoprost Study Group. Eur J Ophthalmol. 2000;10:198-204.
8. Konstas AG, Kozobolis VP, Tersis I, et al. The efficacy and safety of the timolol/dorzolamide fixed combination vs latanoprost in exfoliation glaucoma. Eye. 2003;17:41-46.
9. Bron AM, Emmerich KH. Latanoprost versus combined timolol and dorzolamide. Surv Ophthalmol. 2002;47(Suppl 1):S148-S154.
10. Emmerich KH. Comparison of latanoprost monotherapy to dorzolamide combined with timolol in patients with glaucoma and ocular hypertension. A 3-month randomised study. Graefes Arch Clin Exp Ophthalmol. 2000;238:19-23.
11. Coleman AL, Lerner F, Bernstein P, et al. A 3-month randomized controlled trial of bimatoprost (LUMIGAN) versus combined timolol and dorzolamide (Cosopt) in patients with glaucoma or ocular hypertension. Ophthalmology. 2003;110:2362-2368.
12. Hutzelmann J, Owens S, Shedden A, et al. Comparison of the safety and efficacy of the fixed combination of dorzolamide/timolol and the concomitant administration of dorzolamide and timolol: a clinical equivalence study. International Clinical Equivalence Study Group. Br J Ophthalmol 1998;82:1249-1253.
13. Boyle JE, Ghosh K, Gieser DK, et al. A randomized trial comparing the dorzolamide-timolol combination given twice daily to monotherapy with timolol and dorzolamide. Dorzolamide-Timolol Study Group. Ophthalmology. 1998;105:1945-1951.
14. Strohmaier K, Snyder E, DuBiner H, et al. The efficacy and safety of the dorzolamide-timolol combination versus the concomitant administration of its components. Dorzolamide-Timolol Study Group. Ophthalmology. 1998;105:1936-1944.
15. Clineschmidt CM, Williams RD, Snyder E, et al. A randomized trial in patients inadequately controlled with timolol alone comparing the dorzolamide-timolol combination to monotherapy with timolol or dorzolamide. Dorzolamide-Timolol Combination Study Group. Ophthalmology. 1998;105:1952-1959.
16. Fiscella RG, Geller JL, Gryz LL, et al. Cost considerations of medical therapy for glaucoma. Am J Ophthalmol. 1999;128:426-433.
17. Pajic B. Experience with COSOPT, the fixed combination of timolol and dorzolamide, gained in Swiss ophthalmologists' offices. Curr Med Res Opin. 2003;19:95-101.