Verrucarin A inhibition of MAP kinase activation in a PMA-stimulated promyelocytic leukemia cell line

Marine Drugs

Volumn 3, Issue 2, 2005, Pages 64-73

  Oda, Taiko ^a   Namikoshi, Michio ^b   Akano, Kyoko ^b   Kobayashi, Hisayoshi ^c   Honma, Yoshio ^a   Kasahara, Tadashi ^a  

^a KEIO UNIVERSITY   (Japan)

^b TOKYO UNIVERSITY OF MARINE SCIENCE AND TECHNOLOGY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

HL 60; JNK phosphorylation; MAP kinase; p38 phosphorylation; Verrucarin A

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN SYNTHESIS INHIBITOR; RORIDIN E; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; VERRUCARIN A; VERRUCARIN J;

ARTICLE; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PROMYELOCYTIC LEUKEMIA; SIGNAL TRANSDUCTION; STRESS;

EID: 22544452429     PISSN: 16603397     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md302064     Document Type: Article

References (19)

1. Faulkner, D.J. Marine natural products. Nat. Prod. Rep. 2002, 19, 1-48.
2. Jensen, P.R.; Fenical, W. Secondary metabolites from marine fungi. In Fungi In Marine Environments. (Hyde, K.D., Ed.) Fungal Diversity Research Series 7, Fungal Diversity Press, Hong Kong, 2002; pp. 293-315.
3. Liberra, K.; Lindequist, U. Marine fungi - a prolific resource of biologically active natural products? Pharmazie 1995, 50, 583-588.
4. Kelecom, A. Secondary metabolites from marine microorganisms. Annals Brazil. Acad. Sci. 2002, 74, 151-170.
5. Proksch, P.; Edrada, R.A.; Ebel, R. Drugs from the seas - current status and microbiological implications. Appl. Microbiol. Biotechnol. 2002, 59, 125-134.
6. Jensen, P.R.; Fenical, W. In Drugs from the Sea. (Fusetani N., Ed), Karger, Basel; 2000; pp. 6-29.
7. Faulkner, D.J.; Harper, M.K.; Haygood, M.G.; Salomon, C.E.; Schmidt, E.W. Symbiotic bacteria in sponges: sources of bioactive substances. In Drugs from the Sea (Fusetani N., Ed.), Karger, Basel; 2000; pp. 107-119.
8. Pietra, F. Secondary metabolites from marine microorganisms: bacteria, protozoa, algae and fungi. Achievements and prospects. Nat. Prod. Rep. 1997, 14, 453-464.
9. Davidson, B.S. New dimensions in natural products research: cultured marine microorganisms. Curr. Opin. Biotechnol. 1995, 6, 284-291.
10. Namikoshi, M.; Akano, K.; Kasuga, I.; Mine, Y.; Takahashi, T.; Kobayashi, H. A new macrocyclic trichothecene, 12,13-deoxyroridin E, produced by the marine-derived fungus Myrothecium roridum collected in Palau. J. Nat. Prod. 2001, 64, 396-398.
11. Domzig, W.; Stadler, B.M.; Herberman, R.B. Interleukin 2 dependence of human natural killer (NK) cell activity. J. Immunol. 1983, 130, 1970-1973.
12. Kasahara, T.; Oda, T.; Hatake, K.; Akiyama, M.; Mukaida, N.; Matsushima, K. Interleukin-8 and monocyte chemotactic protein-1 production by a human glioblastoma cell line, T98G in coculture with monocytes: involvement of monocyte-derived interleukin-1alpha. Eur. Cytokine Netw. 1998, 9, 47-55.
13. Shimizu, S.; Nomoto, M.; Naito, S.; Yamamoto, T.; Momose, K. Stimulation of nitric oxide synthase during oxidative endothelial cell injury. Biochem. Pharmacol. 1998, 55, 77-83.
14. Carmichael, J.; DeGraff, W.G.; Gazdar, A.F.; Minna, J.D.; Mitchell, J.B. Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing. Cancer Res. 1987, 47, 939-942.
15. Hiramoto, M.; Shimizu, N.; Sugimoto, K.; Tang, J.; Kawakami, Y.; Ito, M.; Aizawa, S.; Tanaka, H.; Makino, I.; Handa, H. Nuclear targeted suppression of NF-kappa B activity by the novel quinone derivative E3330. J. Immunol. 1998, 160, 810-819.
16. Oda, T.; So, Y.; Sato, Y.; Shimizu, N.; Hand, H.; Yasukochi, Y.; Kasahara, T. Inhibition by (±)-indenestrol A of interferon gamma-stimulated nitric oxide formation in murine macrophge RAW 264.7 cells. Mut. Res. 2003, 534, 187-195.
17. Mukaida, N.; Morita, M.; Ishikawa, Y.; Rice, N.; Okamoto, S.; Kasahara, T.; Matsushima, K. Effects of satratoxins and other macrocyclic trichothecenes on IL-2 production and viability of EL-4 thymoma cells. J. Biol. Chem. 1994, 269, 13289-13295.
18. Lee, M.; Li, S.; Jarvis, B.B.; Pestka, J.J. J. Toxicol. Environ. Health A. 1999, 57, 459-474.
19. Li, G.; Bishop, K.J.; Hall, T.C. J. Biol. Chem. 2001, 276, 2062-2068.