Sirolimus may not cause neurotoxicity in kidney and liver transplant recipients

Neurology

Volumn 65, Issue 2, 2005, Pages 337-338

  Kasner, S E ^a   Sheth, K N ^a   Wu, G F ^a   Messe, S R ^a   Wolf, R L ^a  

^a NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN INHIBITOR; MYCOPHENOLIC ACID; PREDNISONE; RAPAMYCIN; TACROLIMUS;

DIALYSIS DISEQUILIBRIUM SYNDROME; DIALYSIS ENCEPHALOPATHY; EPILEPTIC STATE; HEMODIALYSIS; HUMAN; KIDNEY TRANSPLANTATION; LETTER; LEUKOENCEPHALOPATHY; LIVER TRANSPLANTATION; LUNG TRANSPLANTATION; NEPHROTOXICITY; NEUROLOGICAL COMPLICATION; NEUROTOXICITY; PRIORITY JOURNAL; SEIZURE; TREMOR;

BRAIN; COHORT STUDIES; DEMENTIA, VASCULAR; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY TRANSPLANTATION; LIVER TRANSPLANTATION; LUNG TRANSPLANTATION; RETROSPECTIVE STUDIES; SIROLIMUS; STATUS EPILEPTICUS; TRANSPLANTATION;

EID: 22544447687     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.65.2.337-a     Document Type: Letter

References (6)

1. Maramattom BV, Wijdicks EF. Sirolimus may not cause neurotoxicity in kidney and liver transplant recipients. Neurology 2004;63:1958-1959.
2. Serkova N, Christians U, Flogel U, Pfeuffer J, Leibfritz D. Assessment of the mechanism of astrocyte swelling induced by the macrolide immunosuppressant sirolimus using multinuclear nuclear magnetic resonance spectroscopy. Chem Res Toxicol 1997;10:1359-1363.
3. Product information: rapamune sirolimus [online]. Available at:. Accessed December 23, 2004.
4. Sheth KN, Wu GF, Messe SR, Wolf RL, Kasner SE. Dialysis disequilibrium: another reversible posterior leukoencephalopathy syndrome? Clin Neurol Neurosurg 2003;105:249-252.
5. Kahan BD. Sirolimus-based immunosuppression: present state of the art. J Nephrol 2004;17(suppl 8):S32-S39.
6. Groetzner J, Kur F, Spelsberg F, et al. Airway anastomosis complications in de novo lung transplantation with sirolimus-based immunosuppression. J Heart Lung Transplant 2004;23:632-638.