Effects of olmesartan and enalapril at low or high doses on cardiac, renal and vascular interstitial matrix in spontaneously hypertensive rats

Blood Pressure

Volumn 14, Issue 3, 2005, Pages 184-192

  Porteri, Enzo ^a   Rodella, Luigi ^a   Rizzoni, Damiano ^a   Rezzani, Rita ^a   Paiardi, Silva ^a   Sleiman, Intissar ^a   De Ciuceis, Carolina ^a   Boari, Gianluca E M ^a   Castellano, Maurizio ^a   Bianchi, Rossella ^a   Agabiti Rosei, Enrico ^a  

^a UNIVERSITY OF BRESCIA   (Italy)

Author keywords

ACE inhibitors; Angiotensin II; Collagen; Enalarpil; Interstitial matrix; Olmesartan; Remodeling

Indexed keywords

COLLAGEN; ENALAPRIL; OLMESARTAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE MEASUREMENT; BODY WEIGHT; CALCULATION; CARDIOVASCULAR DISEASE; CARDIOVASCULAR SYSTEM; CONTROLLED STUDY; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG MECHANISM; DRUG RESPONSE; EXTRACELLULAR MATRIX; HEART LEFT VENTRICLE SIZE; HYPERTENSION; IMAGE ANALYSIS; KIDNEY; KIDNEY DYSFUNCTION; MALE; MESENTERIC ARTERY; MYOGRAPHY; NON INVASIVE MEASUREMENT; NONHUMAN; PRIORITY JOURNAL; RAT; RAT STRAIN; SPONTANEOUSLY HYPERTENSIVE RAT; STAINING; SYSTOLIC BLOOD PRESSURE; TISSUE DISTRIBUTION; TREATMENT OUTCOME;

ANIMALS; BLOOD PRESSURE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENALAPRIL; EXTRACELLULAR MATRIX; HEART RATE; HYPERTENSION; IMIDAZOLES; KIDNEY; MALE; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, CARDIAC; RATS; RATS, INBRED SHR; RATS, INBRED WKY; TETRAZOLES;

EID: 22544445282     PISSN: 08037051     EISSN: None     Source Type: Journal    
DOI: 10.1080/08037050510034211     Document Type: Article

References (34)

1. Brilla CG, Pick R, Tan LB, Janicki JS, Weber KT. Remodeling of the rat right and left ventricle in experimental hypertension. Circ Res. 1990;67:1355-1364.
2. Weber KT, Anversa P, Armstrong PW, Brilla CG, Burnett JC, Cruickshank JM, et al. Remodeling and reparation of the cardiovascular system. JACC. 1992;20:3-16.
3. Brilla CG, Zhou G, Matsubara L, Weber KT. Collagen metabolism in cultured adult rat cardiac fibroblasts: Response to angiotensin II and aldosterone. J Mol Cell Cardiol. 1994;26:809-820.
4. Rizzoni D, Porteri E, Piccoli A, Castellano M, Bettoni G, Muiesan ML, et al. Effects of losartan and enalapril on small artery structure in hypertensive rats. Hypertension. 1998;32:305-310.
5. Rizzoni D, Rodella L, Porteri E, Rezzani R, Sleiman I, Paiardi S, et al. Effects of losartan and enalapril at different doses on cardiac and renal interstitial matrix in spontaneously hypertensive rats. Clin Exp Hypertens. 2003;25:427-441.
6. Mezzano S, Ruiz-Ortega M, Egidio I. Angiotensin II and renal fibrosis. Hypertension. 2001;38 (Pt2):635-638.
7. Ichikawa I. Will angiotensin II receptor antagonists be renoprotective in humans? Kidney Int. 1996;50:684-692.
8. Mannisto TK, Karvonen KE, Kerola TV, Ryhanen LJ. Inhibitory effect of the angiotensin converting enzyme inhibitors captopril and enalapril on the conversion of procollagen to collagen. J Hypertens. 2001;19:1835-1839.
9. Rizzoni D, Porteri E, Piccoli A, Castellano M, Muiesan ML, Pasini G, et al. Effects of candesartan cilexetil and enalapril on structural alterations and endothelial function in small resistance arteries of spontaneously hypertensive rats. J Cardiovasc Pharmacol. 1998;32:798-806.
10. Deyl Z, Jelinek J, Macek K, Chaldakov G. Vankov VN Collagen and elastin synthesis in the aorta of spontaneously hypertensive rats. Blood Vessels. 1987;24:313-320.
11. Mizutani K, Ikeda K, Kawai Y, Yamori Y. Biochemical properties and chemical composition of the aorta in genetic hypertensive rats. J Hypertens. 1999;17:481-487.
12. van Gorp AW, Schenau DS, Hoeks AP, Boudier HA, de Mey JG, Reneman RS. In spontaneously hypertensive rats alterations in aortic wall properties precede development of hypertension. Am J Physiol. 2000;278:H1241-H1247.
13. Cox RH. Basis for altered arterial wall mechanics in the spontaneously hypertensive rats. Hypertension. 1981; 3:485-495.
14. Koffi I, Safar ME, Labat C, Lacolley P, Benetos A, Mourad JJ. Arterial structural changes with verapamil in spontaneously hypertensive rats. Am J Hypertens. 1999;12:732-738.
15. Sugano M, Tsuchida K, Sawada S, Makino N. Reduction of plasma angiotensin II to normal levels by antisense oligodeoxynucleotides against liver angiotensinogen cannot completely attenuate vascular remodelling in spontaneously hypertensive rats. J Hypertens. 2000;18:725-731.
16. Brunner HR, Fujita T. Olmesartan: A new antagonist in cardiovascular risk prevention. J Human Hypertens. 2002;16 Suppl 2:S1-S2.
17. Miyazaki M, Takai S. Anti-atherosclerotic efficacy of olmesartan. J Human Hypertens. 2002;16 Suppl 2:S7-S12.
18. Brunner HR. The new oral angiotensin II antagonist olmesartan medoxomil: A concise overview. J Human Hypertens. 2002;16 Suppl 2:S17-S23.
19. Mulvany MJ, Hansen PK, Aalkjaer C. Direct evidence that the greater contractility of resistance vessels in spontaneously hypertensive rats is associated with a narrowed lumen, a thickened media, and an increased number of smooth muscle cell layers. Circ Res. 1978;43:854-864.
20. Mulvany MJ, Aalkjaer C. Structure and function of small arteries. Physiol Rev. 1990;70:921-971.
21. Rizzoni D, Castellano M, Porteri E, Bettoni G, Muiesan ML, Agabiti Rosei E. Delayed development of hypertension after short-term nitrendipine treatment. Hypertension. 1994;24:131-139.
22. Vecchione C, Frata L, Rizzoni D, Norte A, Poulet R, Porteri E, et al. Cardiovascular influences of (1B-adrenergic receptor in mice. Circulation. 2002;105:1700-1707.
23. James J, Bosch KS, Zuyderhoudt FMJ, Houtkooper JM, van Gool J. Histophotometric estimation of volume density of collagen as an indication of fibrosis in rat liver. Histochemistry. 1986;85:129-133.
24. Canham PB, Talman EA, Finlay HM, Dixon JD. Medial collagen organization in human arteries of the heart and brain by polarized light microscopy. Connective Tissue Res. 1991;26:121-134.
25. Rizzoni D, Rossi GP, Porteri E, Sticchi E, Rodella L, Rezzani R, et al. Bradykinin and matrix metalloproteinases are involved in prevention of structural alterations of rat small arteries during inhibition of ACE and NEP. J Hypertens. 2004;22:1-8.
26. Brilla CG, Zhou G, Matsubara L, Weber KT. Collagen metabolism in cultured adult rat cardiac fibroblasts: Response to angiotensin II and aldosterone. J Mol Cell Cardiol. 1994;26:809-820.
27. Dostal DE. Regulation of cardiac collagen. Angiotensin and cross-talk with local growth factors. Hypertension. 2001;37:841-844.
28. Brilla CG, Zhou G, Matsubara L, Weber KT. Cardioreparative effects of lisinopril in rats with genetic hypertension and left ventricular hypertrophy. Circulation. 1991;83:1771-1779.
29. Rizzoni D, Castellano M, Porteri E, Bettoni G, Muiesan ML, Cinelli A, et al. Effects of low and high doses of fosinopril on the structure and function of resistance arteries. Hypertension. 1995;26:118-123.
30. Brilla CG, Janicki JS, Weber KT. Impaired diastolic function and coronary reserve in genetic hypertension: Role of interstitial fibrosis and medial thickening of intramyocardial coronary arteries Circ Res. 1991;69:107-117.
31. Francischetti A, Ono H, Frohlich ED. Renoprotective effects of felodipine and/or enalapril in spontaneously hypertensive rats with and without L-NAME. Hypertension. 1988;31:795-801.
32. Casellas D, Benhamed S, Artuso A, Jover B. Candesartan and progression of preglomerular lesions in L-NAME hypertensive rats. J Am Soc Nephrol. 1999;10:S230-S233.
33. Michel JB, Xu Y, Blot S, Philippe M, Chatellier G. Improved survival in rats administered L-NAME due to converting enzyme inhibition. J Cardiovasc Pharmacol. 1996; 28:142-148.
34. Rizzoni D, Castellano M, Porteri E, Bettoni G, Muiesan ML, Agabiti Rosei E. Delayed development of hypertension after short-term nitrendipine treatment. Hypertension. 1994; 24:131-139.