Haploinsufficiency of cytochrome P450 17α-hydroxylase/17,20 lyase (CYP17) causes infertility in male mice

Molecular Endocrinology

Volumn 19, Issue 9, 2005, Pages 2380-2389

  Liu, Ying ^a   Yao, Zhi Xing ^a   Bendavid, Claude ^a   Borgmeyer, Carol ^a   Han, Zeqiu ^a   Cavalli, Luciane R ^a   Chan, Wai Yee ^a,b   Folmer, Janet ^c   Zirkin, Barry R ^c   Haddad, Bassem R ^a   Gallicano, G Ian ^a   Papadopoulos, Vassilios ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; CYTOCHROME P450 17; MESSENGER RNA; STEROID 17ALPHA MONOOXYGENASE; TESTOSTERONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHIMERA; CIRCULATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENDER; GENE DELETION; GENE EXPRESSION; GENE TARGETING; GERM CELL; HAPLOTYPE; HETEROZYGOSITY; IN VIVO STUDY; LEYDIG CELL; MALE; MALE INFERTILITY; MATING; MOUSE; MOUSE STRAIN; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SEXUAL BEHAVIOR; SPERMATOGENESIS; SPERMATOZOON MATURATION; TESTIS; TESTIS CELL;

ALLELES; ANIMALS; CHIMERA; GENE DELETION; INFERTILITY, MALE; LEYDIG CELLS; MALE; MICE; MICE, KNOCKOUT; RNA, MESSENGER; SPERM MOTILITY; SPERMATOZOA; STEROID 17-ALPHA-HYDROXYLASE; STEROIDS;

EID: 22444450635     PISSN: 08888809     EISSN: 08888809     Source Type: Journal    
DOI: 10.1210/me.2004-0418     Document Type: Article

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