Ionization energies of multiply protonated polypeptides obtained by tandem ionization in Fourier transform mass spectrometers

Journal of Mass Spectrometry

Volumn 37, Issue 11, 2002, Pages 1141-1144

  Budnik, Bogdan A ^a   Tsybin, Youri O ^b   Häkansson, Per ^b   Zubarev, Roman A ^a,b  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

Electron impact; Fourier transform ion cyclotron resonance; Ionization energy; Odd electron ions; Peptides

Indexed keywords

ELECTRONS; FOURIER TRANSFORM INFRARED SPECTROSCOPY; INSULIN; IONIZATION;

LASER DESORPTION;

POLYPEPTIDES;

ARGIPRESSIN; INSULIN; ION; MELITTIN; POLYPEPTIDE; RENIN; SUBSTANCE P;

ARTICLE; BETA CHAIN; CALCULATION; CELL; CHEMICAL REACTION; CONTROLLED STUDY; ELECTRON; ENERGY; FOURIER ANALYSIS; IONIZATION; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTON TRANSPORT;

ANGIOTENSINOGEN; FOURIER ANALYSIS; INSULIN; IONS; MASS SPECTROMETRY; MELITTEN; PEPTIDES; PROTONS; SUBSTANCE P; VASOPRESSINS;

EID: 2242486479     PISSN: 10765174     EISSN: None     Source Type: Journal    
DOI: 10.1002/jms.376     Document Type: Article

References (14)

1. Karas M, Bahr U, Hillenkamp F. Laser Desorption Ionization of Proteins with Molecular Masses Exceeding 10000 Da. Int. J. Mass Spectrom. Ion Processes 1989; 92: 231.
2. Fenn JB, Mann M, Meng CK, Wong SF, Whitehouse CM. Electrospray Ionization for Mass-Spectrometry of Large Biomolecules, Science 1989; 246: 64.
3. Iavarone AT, Jurchen JC, Williams ER. Supercharged protein and peptide lone formed by electrospray ionization. Anal. Chem. 2001; 73: 1455.
4. Tang K, Allman SL, Chen CH. Laser Mass-Spectrometry for Biopolymers, Inst. Phys. Conf. Ser. 1992; 128: 289.
5. Budnik BA, Zubarev RA. Ion production from protonated polypeptides by electron impact: observation and determination of ionization energies and a cross-section. Chem. Phys. Lett. 2000; 316: 19.
6. Berkowitz J. The Quantum Yield of Ionization. Phys. Essays 2000; 13: 248.
7. Zubarev RA, Budnik BA, Nielsen ML. Tandem Ionization Mass Spectrometry of Biomolecules. Eur. J. Mass Spectrom. 2000; 6: 235.
8. Nilsson S, Wetterhall M, Bergquist J, Nyholm L, Markides KE. A simple and robust conductive graphite coating for sheathless electrospray emitters used in capillary electrophoresis/mass spectrometry. Rapid Commun. Mass Spectrom. 2001; 15: 1997.
9. Tsybin YO, Hakansson P, Budnik BA, Haselmann KF, Kjeldsen V, Gorshkov M, Zubarev RA. Improved Low-energy Injection Systems for High Rate Electron Capture Dissociation in Fourier Transform Ion Cyclotron Resonance Mass Spectrometry. Rapid Commun. Mass Spectrom. 2001; 15: 1849.
10. Kaltashov IA, Fabris D, Fenselau CC. Assessment of Gas-Phase Basicities of Protonated Peptides by the Kinetic Method. J. Phys. Chem. 1995; 99: 10046.
11. Kaltashov IA, Fenselau C. Thermochemistry of multiply charged melittin in the gas phase determined by the modified kinetic method. Rapid Commun. Mass Spectrom. 1996; 10: 857.
12. Carr SR, Cassady CJ. Reactivity and gas-phase acidity determinations of small peptide ions consisting of 11 to 14 amino acid residues. J. Mass Spectrom. 1997; 32: 959.
13. Lias SG, Bartmess JE. In NIST Chemistry Webbook, NIST Standard Reference Database No. 69, Mallald WG, Lingstrom PJ (eds). National Institute of Standards and Technology, Gaithersburg, MD, 2000.
14. Campbell S, Beauchamp JL, Rempe M, Lichtenberger DL. Correlations of Lone Pair Ionization Energies with Proton Affinities of Amino-Acid and Related Compounds Site Specificity of Protonation. Int. J. Mass Spectrom. Ion Processes 1992; 117: 83.