The endocannabinoid anandamide inhibits neuronal progenitor cell differentiation through attenuation of the Rap1/B-Raf/ERK pathway

Journal of Biological Chemistry

Volumn 277, Issue 48, 2002, Pages 46645-46650

  Rueda, Daniel ^a   Navarro, Beatriz ^b   Martínez Serrano, Alberto ^b   Guzmán, Manuel ^a   Galve Roperh, Ismael ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ATTENUATION; BRAIN; CELLS; ENZYME INHIBITION;

NEUROGENESIS;

BIOCHEMISTRY;

ANANDAMIDE; CANNABINOID 1 RECEPTOR; METHANANDAMIDE; MITOGEN ACTIVATED PROTEIN KINASE; NERVE GROWTH FACTOR RECEPTOR; RAP PROTEIN; RIMONABANT;

ANIMAL CELL; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; CORPUS STRIATUM; ENZYME ACTIVITY; HIPPOCAMPUS; NERVE CELL DIFFERENTIATION; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

ANIMALS; ARACHIDONIC ACIDS; CELL DIFFERENTIATION; CELLS, CULTURED; ENDOCANNABINOIDS; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MITOGEN-ACTIVATED PROTEIN KINASES; NERVE GROWTH FACTOR; NEURONS; PC12 CELLS; POLYUNSATURATED ALKAMIDES; PROTO-ONCOGENE PROTEINS B-RAF; PROTO-ONCOGENE PROTEINS C-RAF; RAP1 GTP-BINDING PROTEINS; RATS; RATS, WISTAR; STEM CELLS;

ANIMALIA;

EID: 2242448020     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M206590200     Document Type: Article

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